{
  "id": 19495,
  "label": "thrombotic microangiopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019737",
  "properties": {
    "xrefs": [
      "GARD:0019227",
      "ICD10CM:M31.1",
      "ICD9:446.6",
      "MEDGEN:403479",
      "MESH:D057049",
      "MedDRA:10043645",
      "NCIT:C62605",
      "Orphanet:93573",
      "SCTID:126729006",
      "UMLS:C2717961"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "The syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 3738,
      "label": "blood coagulation disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1247",
          "EFO:0009314",
          "ICD9:286",
          "ICD9:286.9",
          "ICD9:287.8",
          "MEDGEN:604",
          "MESH:D001778",
          "NCIT:C2902",
          "SCTID:64779008",
          "UMLS:C0005779"
        ],
        "synonyms": [
          "blood coagulation disorder",
          "coagulation defect",
          "coagulation disorder",
          "coagulation disorder, blood",
          "coagulation disorders, blood",
          "coagulopathy",
          "disorder, blood coagulation",
          "disorders, blood coagulation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood."
      },
      "child_count": 8,
      "reference_id": "MONDO:0001531"
    }
  ],
  "children": [
    {
      "id": 16818,
      "label": "atypical hemolytic-uremic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        5701,
        19495,
        25595
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080301",
          "GARD:0008702",
          "MEDGEN:444141",
          "MESH:D065766",
          "NANDO:1200473",
          "NANDO:1200474",
          "NANDO:2200131",
          "NANDO:2200641",
          "NCIT:C123223",
          "NORD:822",
          "Orphanet:2134",
          "UMLS:C2931788"
        ],
        "synonyms": [
          "Atypical Hemolytic Uremic Syndrome",
          "D-HUS",
          "aHUS",
          "atypical HUS",
          "atypical hemolytic uremic syndrome",
          "hemolytic-uremic syndrome without diarrhea",
          "hemolytic-uremic syndrome without diarrhoea",
          "non-diarrhea-associated hemolytic uremic syndrome",
          "D-minus hemolytic uremic syndrome (D-HUS)",
          "HUS, atypical"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare, genetic thrombotic microangiopathy due to dysregulation of the alternative complement pathway and characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal dysfunction."
      },
      "child_count": 16,
      "reference_id": "MONDO:0016244"
    },
    {
      "id": 23244,
      "label": "thrombocytopenic purpura",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4196,
        4662,
        6778,
        19495
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025866",
          "MEDGEN:208992",
          "MESH:D011696",
          "NANDO:2100188",
          "NCIT:C26870",
          "SCTID:302873008",
          "UMLS:C0857305"
        ],
        "synonyms": [
          "thrombocytopenic purpura",
          "purpura, thrombopenic",
          "purpuras, thrombocytopenic",
          "purpuras, thrombopenic",
          "thrombocytopenic purpuras",
          "thrombopenic purpura",
          "thrombopenic purpuras"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Purpura associated with a reduction in circulating blood platelets which can result from a variety of factors."
      },
      "child_count": 8,
      "reference_id": "MONDO:0043768"
    }
  ],
  "roots": [
    {
      "id": 3738,
      "label": "blood coagulation disease"
    }
  ]
}