{
  "id": 19498,
  "label": "acquired thrombotic thrombocytopenic purpura",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019740",
  "properties": {
    "xrefs": [
      "GARD:0004607",
      "MEDGEN:391723",
      "MESH:C536901",
      "NANDO:1200318",
      "NANDO:1200319",
      "NCIT:C131653",
      "Orphanet:93585",
      "SCTID:438476003",
      "UMLS:C2584778"
    ],
    "synonyms": [
      "TTP",
      "purpura, thrombotic thrombocytopenic",
      "acquired ADAMTS13 deficiency",
      "acquired TTP",
      "acquired thrombotic thrombocytopenic purpura",
      "autoimmune thrombotic thrombocytopenic purpura",
      "Moschowitz syndrome",
      "idiopathic thrombotic thrombocytopenic purpura"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Acquired thrombotic thrombocytopenic purpura is the non-hereditary form of thrombotic thrombocytopenic purpura (TTP), characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and single or multiple organ failure of variable severity."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3439,
      "label": "acquired thrombocytopenia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4196
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11126",
          "ICD9:287.4",
          "MEDGEN:509570",
          "SCTID:74576004",
          "UMLS:C0154301",
          "icd11.foundation:526155201"
        ],
        "synonyms": [
          "acquired thrombocytopenia",
          "secondary thrombocytopenia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An instance of thrombocytopenia that is acquired during the lifetime of the individual."
      },
      "child_count": 1,
      "reference_id": "MONDO:0001198"
    },
    {
      "id": 18824,
      "label": "thrombotic thrombocytopenic purpura",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4413,
        23244
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10772",
          "GARD:0016659",
          "MEDGEN:48266",
          "MESH:D011697",
          "MedDRA:10043648",
          "NANDO:1200316",
          "NANDO:2100189",
          "NANDO:2200649",
          "NCIT:C78797",
          "NORD:1769",
          "Orphanet:54057",
          "SCTID:78129009",
          "UMLS:C0034155",
          "icd11.foundation:1708277768"
        ],
        "synonyms": [
          "Moschcowitz disease",
          "Moschowitz disease",
          "TTP"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Thrombotic thrombocytopenic purpura (TTP) is an aggressive and life-threatening form of thrombotic microangiopathy (TMA) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and organ failure of variable severity and is comprised of congenital TTP and acquired TTP."
      },
      "child_count": 4,
      "reference_id": "MONDO:0018896"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3439,
      "label": "acquired thrombocytopenia"
    },
    {
      "id": 18824,
      "label": "thrombotic thrombocytopenic purpura"
    }
  ]
}