{
  "id": 19523,
  "label": "myelomeningocele",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019773",
  "properties": {
    "xrefs": [
      "DOID:0060326",
      "GARD:0003475",
      "HP:0002475",
      "MEDGEN:7538",
      "MESH:D008591",
      "NANDO:1200509",
      "NANDO:2100215",
      "NANDO:2200814",
      "Orphanet:93969",
      "SCTID:414667000",
      "UMLS:C0025312",
      "icd11.foundation:1200528084"
    ],
    "synonyms": [
      "meningomyelocele"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Myelomeningocele is the most severe form of spina bifida. It happens when parts of the spinal cord and nerves come through the open part of the spine. It causes nerve damage and other disabilities. Seventy to ninety percent of children with this condition also have too much fluid on their brains (hydrocephalus). This happens because fluid that protects the brain and spinal cord is unable to drain like it should. The fluid builds up, causing pressure and swelling. Without treatment, a persons head grows too big, and theymay have brain damage. Other disorders of the spinal cord may be seen, including syringomyelia and hip dislocation. The cause of myelomeningocele is unknown. However, low levels of folic acid in a woman's body before and during early pregnancy is thought to play a part in this type of birth defect."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 17449,
      "label": "spina bifida cystica",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020958",
          "MEDGEN:21277",
          "MESH:D016137",
          "MedDRA:10071011",
          "NANDO:1200509",
          "NANDO:2100215",
          "NANDO:2200814",
          "NCIT:C101201",
          "Orphanet:268744",
          "UMLS:C0037917",
          "icd11.foundation:979482551"
        ],
        "synonyms": [
          "meningomyelocele",
          "myelomeningocele",
          "open spina bifida",
          "spina bifida aperta",
          "spina bifida manifesta",
          "spina bifida, open"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A congenital abnormality in which the spinal cord and meninges protrude through a defect in the spinal column. The protrusion is above the skin surface."
      },
      "child_count": 5,
      "reference_id": "MONDO:0017069"
    }
  ],
  "children": [
    {
      "id": 17450,
      "label": "total spina bifida cystica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020959",
          "Orphanet:268748"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017070"
    },
    {
      "id": 17451,
      "label": "thoracolumbosacral spina bifida cystica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020960",
          "Orphanet:268752"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017071"
    },
    {
      "id": 17452,
      "label": "lumbosacral spina bifida cystica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020961",
          "Orphanet:268758"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017072"
    },
    {
      "id": 17453,
      "label": "cervical spina bifida cystica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020962",
          "Orphanet:268762"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017073"
    },
    {
      "id": 17454,
      "label": "cervicothoracic spina bifida cystica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020963",
          "Orphanet:268766"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017074"
    },
    {
      "id": 17455,
      "label": "upper thoracic spina bifida cystica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020964",
          "Orphanet:268770"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017075"
    },
    {
      "id": 25679,
      "label": "true myelomeningocele",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026834",
          "MEDGEN:1843418",
          "Orphanet:645383",
          "UMLS:C5816713"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare open neural tube defect characterized by no other malformation than myelomeningocele (spina bifida with a neural placode exposed at the top of a non-epidermised dysplasic meninges sac and Chiari II malformation)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0957453"
    },
    {
      "id": 25680,
      "label": "hemi-myelomeningocele",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026835",
          "MEDGEN:1843407",
          "Orphanet:645388",
          "UMLS:C5816710"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A very rare form of composite dysraphism characterized by the presence of a split cord malformation and a myelomeningocele on one of the two hemicords. Hemicords can be in a single dural sac or in two separated dural sacs. Other spinal cord malformations can be associated. Due to the comparable prognosis it is considered as a subtype of myelomeningocele."
      },
      "child_count": 0,
      "reference_id": "MONDO:0957454"
    }
  ],
  "roots": [
    {
      "id": 17449,
      "label": "spina bifida cystica"
    }
  ]
}