{
  "id": 19546,
  "label": "twin to twin transfusion syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019805",
  "properties": {
    "xrefs": [
      "DOID:13576",
      "EFO:1001221",
      "GARD:0000325",
      "MEDGEN:777055",
      "MESH:D005330",
      "MedDRA:10058328",
      "NCIT:C113824",
      "NORD:2021",
      "Orphanet:95431",
      "SCTID:13404009",
      "UMLS:C2909036",
      "icd11.foundation:850604370"
    ],
    "synonyms": [
      "Feto-fetal transfusion syndrome",
      "Twin Anemia Polycythemia Sequence",
      "Twin-Twin transfusion syndrome",
      "foetal blood loss from foetal haemorrhage into co-twin",
      "foetal haemorrhage into co-twin",
      "placental transfusion syndrome",
      "stuck Twin syndrome",
      "twin-to-twin transfusion syndrome",
      "Fetofetal transfusion syndrome",
      "TTTS",
      "fetal transfusion syndrome",
      "foetal transfusion syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Twin twin transfusion syndrome (TTTS) is a rare condition seen in twin monochorionic pregnancies, typically developing during the 15-26 week gestation period and usually due to unbalanced intertwin placental anastomoses, where an unequal exchange of blood between twins causes oligohydramnios in one sac and polyhydramnios in the other which can lead to a high perinatal mortality rate and a high rate of disability in survivors if left untreated"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 3480,
      "label": "neonatal anemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4394
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11244",
          "MEDGEN:1530",
          "MESH:D000751",
          "SCTID:234350007",
          "UMLS:C0002891"
        ],
        "synonyms": [
          "anemia neonatal"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "The mildest form of erythroblastosis fetalis in which anemia is the chief manifestation."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001240"
    },
    {
      "id": 6778,
      "label": "immune system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2914",
          "EFO:0000540",
          "ICD9:279",
          "ICD9:279.1",
          "ICD9:279.10",
          "ICD9:279.19",
          "ICD9:279.4",
          "ICD9:279.49",
          "ICD9:279.8",
          "ICD9:279.9",
          "MEDGEN:5759",
          "MESH:D007154",
          "NANDO:1100004",
          "NANDO:2100202",
          "NCIT:C3507",
          "SCTID:414029004",
          "UMLS:C0021053"
        ],
        "synonyms": [
          "disease of immune system",
          "disease or disorder of immune system",
          "disorder of immune system",
          "immune disease",
          "immune disorder",
          "immune dysfunction",
          "immune system disease or disorder",
          "immune system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A disorder resulting from an abnormality in the immune system."
      },
      "child_count": 47,
      "reference_id": "MONDO:0005046"
    }
  ],
  "children": [
    {
      "id": 23043,
      "label": "twin reversal arterial perfusion syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19546
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025840",
          "MEDGEN:736778",
          "SCTID:417006004",
          "UMLS:C1562817"
        ],
        "synonyms": [
          "twin reversal arterial perfusion syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0041755"
    }
  ],
  "roots": [
    {
      "id": 3480,
      "label": "neonatal anemia"
    },
    {
      "id": 6778,
      "label": "immune system disorder"
    }
  ]
}