{
  "id": 19551,
  "label": "toxic epidermal necrolysis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019810",
  "properties": {
    "xrefs": [
      "EFO:0004775",
      "GARD:0007743",
      "ICD9:695.15",
      "MEDGEN:4501",
      "MedDRA:10044223",
      "NANDO:1200246",
      "NANDO:2201007",
      "NCIT:C79777",
      "Orphanet:95455",
      "SCTID:23067006",
      "UMLS:C0014518",
      "icd11.foundation:1575072695",
      "icd11.foundation:195467267"
    ],
    "synonyms": [
      "SJS-TEN",
      "TEN",
      "toxic epidermolysis",
      "Lyell syndrome",
      "Lyell's syndrome",
      "Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Toxic epidermal necrolysis (TEN) is an acute and severe skin disease with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 17704,
      "label": "toxic dermatosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021171",
          "MEDGEN:1842825",
          "Orphanet:293815",
          "UMLS:C5680999"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0017396"
    }
  ],
  "children": [
    {
      "id": 18359,
      "label": "Stevens-Johnson syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        19551
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050426",
          "EFO:0004276",
          "GARD:0007700",
          "ICD10CM:L51.1",
          "ICD9:695.12",
          "ICD9:695.13",
          "MEDGEN:20955",
          "MESH:D013262",
          "MedDRA:10042033",
          "NANDO:1200245",
          "NANDO:2100290",
          "NANDO:2201006",
          "NCIT:C79484",
          "OMIM:608579",
          "Orphanet:36426",
          "SCTID:73442001",
          "UMLS:C0038325",
          "icd11.foundation:450167795"
        ],
        "synonyms": [
          "Dermatostomatitis, Stevens Johnson type",
          "Stevens Johnson syndrome",
          "Stevens-Johnson syndrome, susceptibility to",
          "erythema multiforme major",
          "hypersensitivity syndrome, carbamazepine-induced, susceptibility to",
          "severe cutaneous adverse reaction, susceptibility to",
          "toxic Epidermal necrolysis, susceptibility to"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Stevens-Johnson syndrome is a limited form of toxic epidermal necrolysis characterized by destruction and detachment of the skin epithelium and mucous membranes involving less than 10% of the body surface area."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018229"
    },
    {
      "id": 18818,
      "label": "Lyell syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19551
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018696",
          "Orphanet:537"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Lyell syndrome is an extended form of toxic epidermal necrolysis characterized by destruction and detachment of the skin epithelium and mucous membranes involving more than 30% of the body surface area."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018890"
    },
    {
      "id": 23415,
      "label": "Stevens-Johnson syndrome/toxic epidermal necrolysis overlap syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7238,
        19551
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022066",
          "MEDGEN:783034",
          "Orphanet:506784",
          "UMLS:C3661878",
          "icd11.foundation:496418968"
        ],
        "synonyms": [
          "SJS/TEN overlap syndrome",
          "Stevens-Johnson/TEN overlap syndrome",
          "Stevens-Johnson/toxic epidermal necrolysis overlap syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0044739"
    }
  ],
  "roots": [
    {
      "id": 17704,
      "label": "toxic dermatosis"
    }
  ]
}