{
  "id": 19559,
  "label": "univentricular cardiopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019820",
  "properties": {
    "xrefs": [
      "GARD:0019269",
      "MEDGEN:1843389",
      "Orphanet:95483",
      "UMLS:C5681576"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 19327,
      "label": "congenital heart malformation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005269",
          "MEDGEN:1680993",
          "Orphanet:88991",
          "UMLS:C3649636"
        ],
        "synonyms": [
          "congenital heart malformation",
          "disorder of heart development",
          "heart development disease",
          "congenital non-syndromic heart malformation",
          "rare congenital non-syndromic heart malformation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease that has its basis in the disruption of heart development."
      },
      "child_count": 26,
      "reference_id": "MONDO:0019512"
    }
  ],
  "children": [
    {
      "id": 6680,
      "label": "hypoplastic left heart syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7229,
        19559,
        24272,
        24336
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9955",
          "GARD:0006739",
          "ICD10CM:Q23.4",
          "ICD9:746.7",
          "MEDGEN:57746",
          "MESH:D018636",
          "MedDRA:10021076",
          "NANDO:1200705",
          "NANDO:2100071",
          "NANDO:2200249",
          "NCIT:C98894",
          "NORD:1277",
          "OMIMPS:241550",
          "Orphanet:2248",
          "SCTID:62067003",
          "UMLS:C0152101",
          "icd11.foundation:1811800027"
        ],
        "synonyms": [
          "HLHS"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Hypoplastic left heart syndrome (HLHS) refers to the abnormal development of the left-sided cardiac structures, resulting in obstruction to blood flow from the left ventricular outflow tract. In addition, the syndrome includes underdevelopment of the left ventricle, aorta, and aortic arch, as well as mitral atresia or stenosis."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004933"
    },
    {
      "id": 16294,
      "label": "univentricular heart",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19559
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018725",
          "ICD9:746.89",
          "MEDGEN:488862",
          "MESH:D000080039",
          "MedDRA:10045545",
          "NANDO:1200704",
          "NANDO:2200250",
          "Orphanet:1464",
          "SCTID:253283000",
          "UMLS:C0344622",
          "icd11.foundation:1786413029"
        ],
        "synonyms": [
          "Double inlet left ventricle"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Univentricular heart (UVH) is a severe congenital cardiac malformation characterized by both atria related entirely or almost entirely to one functionally single ventricular chamber. The clinical manifestations include congestive heart failure, failure to thrive, cyanosis, hypoxemia and neurodevelopmental disabilities."
      },
      "child_count": 1,
      "reference_id": "MONDO:0015451"
    },
    {
      "id": 19776,
      "label": "hypoplastic right heart syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        19559
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070315",
          "GARD:0002922",
          "ICD10CM:Q22.6",
          "ICD9:746.89",
          "MEDGEN:83376",
          "MedDRA:10050053",
          "MedDRA:10064962",
          "NCIT:C99053",
          "Orphanet:98723",
          "SCTID:268180007",
          "UMLS:C0344963"
        ],
        "synonyms": [
          "right hypoplastic heart syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Hypoplastic right-heart syndrome (HRHS) is a rare, cyanotic congenital heart malformation caused by underdevelopment of the right-sided heart structures (tricuspid valve, RV, pulmonary valve, and pulmonary artery) commonly associated with an atrial septal defect, ostium secundum type. Pulmonary blood flow is diminished and right-to-left shunting occurs at the atrial level, leading to dyspnea, fatigue, atrial arrhythmias, right-sided heart failure, hypoxemia, repeated miscarriages that were mostly due to hypoxemia and cyanosis. Two subtypes of HRHS have been characterized: pulmonary atresia-intact ventricular septum and right ventricular hypoplasia."
      },
      "child_count": 4,
      "reference_id": "MONDO:0020291"
    }
  ],
  "roots": [
    {
      "id": 19327,
      "label": "congenital heart malformation"
    }
  ]
}