{
  "id": 19708,
  "label": "infectious disorder of the nervous system",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020010",
  "properties": {
    "xrefs": [
      "ICD9:349.89",
      "MEDGEN:108926",
      "NCIT:C27590",
      "Orphanet:98010",
      "SCTID:128116006",
      "UMLS:C0597039"
    ],
    "synonyms": [
      "nervous system infectious disease",
      "nervous system infectious disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A infectious disease that involves the nervous system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 6799,
      "label": "nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:863",
          "EFO:0000618",
          "ICD10CM:G00-G99",
          "ICD9:349.89",
          "ICD9:349.9",
          "MEDGEN:14336",
          "MESH:D009422",
          "NCIT:C26835",
          "SCTID:118940003",
          "UMLS:C0027765",
          "Wikipedia:Nervous_system_disease"
        ],
        "synonyms": [
          "disease of nervous system",
          "disease or disorder of nervous system",
          "disorder of nervous system",
          "nervous system disease",
          "nervous system disease or disorder",
          "nervous system disorder",
          "neurologic disease",
          "neurologic disorder",
          "neurological disease",
          "neurological disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves."
      },
      "child_count": 72,
      "reference_id": "MONDO:0005071"
    },
    {
      "id": 7200,
      "label": "infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050117",
          "EFO:0005741",
          "ICD10CM:A00-B99",
          "ICD9:079.0",
          "ICD9:136.8",
          "ICD9:136.9",
          "IDO:0000436",
          "MEDGEN:1057",
          "MESH:D003141",
          "NCIT:C26726",
          "SCTID:40733004",
          "UMLS:C0009450"
        ],
        "synonyms": [
          "communicable disease",
          "infection",
          "infectious",
          "infectious disease",
          "infectious diseases and manifestations",
          "infectious disorder",
          "transmissible disease",
          "clinical infection",
          "disease by infectious agent"
        ],
        "definition": "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact."
      },
      "child_count": 35,
      "reference_id": "MONDO:0005550"
    }
  ],
  "children": [
    {
      "id": 3166,
      "label": "cytomegalovirus retinitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4749,
        6856,
        16683,
        19708,
        20248
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080160",
          "EFO:1001302",
          "GARD:0009531",
          "MEDGEN:61532",
          "MESH:D017726",
          "NCIT:C50521",
          "SCTID:22455005",
          "UMLS:C0206178",
          "icd11.foundation:315493536"
        ],
        "synonyms": [
          "Cytomegaloviral Retinitis",
          "Cytomegalovirus caused retinitis",
          "Cytomegalovirus retinitis",
          "Retinitis, Cytomegaloviral",
          "cytomegalovirus retinitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Infection of the retina by cytomegalovirus characterized by retinal necrosis, hemorrhage, vessel sheathing, and retinal edema. Cytomegalovirus retinitis is a major opportunistic infection in aids patients and can cause blindness."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000878"
    },
    {
      "id": 3500,
      "label": "histoplasmosis retinitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4236,
        4749,
        16683,
        19708,
        20246
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11316",
          "GARD:0022912",
          "ICD9:115.92",
          "MEDGEN:509240",
          "SCTID:187058000",
          "UMLS:C0153278"
        ],
        "synonyms": [
          "Histoplasma capsulatum caused retinitis",
          "Histoplasma capsulatum retinitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "An retinitis caused by infection with Histoplasma capsulatum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001263"
    },
    {
      "id": 7180,
      "label": "tetanus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2837,
        19708,
        21394
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11338",
          "EFO:0005593",
          "GARD:0005144",
          "ICD9:037",
          "MEDGEN:21489",
          "MESH:D013742",
          "MedDRA:10043376",
          "NCIT:C85185",
          "Orphanet:3299",
          "SCTID:276202003",
          "SCTID:76902006",
          "UMLS:C0039614",
          "icd11.foundation:1793762788"
        ],
        "synonyms": [
          "Clostridium tetani caused infectious disease of the nervous system",
          "Clostridium tetani infectious disease of the nervous system",
          "lockjaw"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005526"
    },
    {
      "id": 7488,
      "label": "ophthalmic herpes zoster",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5448,
        7250,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007403",
          "GARD:0009721",
          "ICD9:053.29",
          "MEDGEN:9236",
          "MESH:D006563",
          "SCTID:87513003",
          "UMLS:C0019364"
        ],
        "synonyms": [
          "herpes zoster ophthalmicus",
          "HZO",
          "Herpes zoster ophthalmicus (HZO)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Virus infection of the Gasserian ganglion and its nerve branches characterized by pain and vesicular eruptions with much swelling. Ocular involvement is usually heralded by a vesicle on the tip of the nose. This area is innervated by the nasociliary nerve."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005883"
    },
    {
      "id": 7569,
      "label": "tabes dorsalis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6690,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10027",
          "GARD:0008730",
          "ICD10CM:A52.11",
          "ICD9:094.0",
          "MEDGEN:21065",
          "MESH:D013606",
          "NCIT:C35057",
          "SCTID:316841006",
          "UMLS:C0039223",
          "icd11.foundation:1131342025"
        ],
        "synonyms": [
          "syphilitic myelopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A form of neurosyphilis characterized by slowly progressive degeneration of the spinal cord. Signs and symptoms include pain, ataxia, loss of coordination, personality changes, blindness, urinary incontinence, dementia, and degeneration of the joints."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005977"
    },
    {
      "id": 7573,
      "label": "tick paralysis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7572,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11285",
          "EFO:0007509",
          "GARD:0007771",
          "MEDGEN:52752",
          "MESH:D013985",
          "SCTID:74225001",
          "UMLS:C0040197"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Paralysis caused by a neurotropic toxin secreted by the salivary glands of ticks."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005981"
    },
    {
      "id": 9363,
      "label": "tropical spastic paraparesis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7417,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:321",
          "EFO:0007527",
          "GARD:0008208",
          "ICD10CM:G04.1",
          "ICD9:323.01",
          "MEDGEN:18298",
          "MESH:D015493",
          "MedDRA:10044696",
          "NANDO:1200206",
          "OMIM:159580",
          "Orphanet:289326",
          "SCTID:714279000",
          "UMLS:C0030481",
          "icd11.foundation:1043229589"
        ],
        "synonyms": [
          "HAM/TSP",
          "HTLV-1-associated myelopathy/tropical spastic paraparesis",
          "Human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis",
          "Human T-lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis",
          "TSP",
          "ham/TSP",
          "tropical spastic paraplegia",
          "HTLV-1 associated myelopathy/tropical spastic paraparesis",
          "Human T-cell leukaemia virus type 1 associated myelopathy/tropical spastic paraparesis",
          "Human T-cell leukemia virus type 1 associated myelopathy/tropical spastic paraparesis",
          "familial spastic paraparesis, HTLV-1-associated",
          "ham",
          "myelopathy, HTLV-1-associated",
          "tropical spastic paraparesis (formerly)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Tropical spastic paraparesis is a chronic systemic immune-mediated inflammatory myeloneuropathy, more frequently reported in women than in men, that usually presents in adulthood with slowly progressive spastic paraparesis of the lower limbs, bladder and bowel dysfunction, and sensory disturbances in the lower extremities (e.g. paresthesia and dysesthesia) and that is associated with a human T-cell lymphotropic virus type 1 (HTLV-1) infection."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008039"
    },
    {
      "id": 19048,
      "label": "rabies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6834,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11260",
          "GARD:0007516",
          "ICD10CM:A82",
          "ICD10WHO:A82",
          "ICD9:071",
          "MEDGEN:48308",
          "MESH:D011818",
          "MedDRA:10037742",
          "NCIT:C28182",
          "NORD:1644",
          "Orphanet:770",
          "SCTID:14168008",
          "UMLS:C0034494",
          "icd11.foundation:854762584"
        ],
        "synonyms": [
          "lyssa"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Rabies is a viral zoonosis leading to a fatal encephalopathy if not treated."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019173"
    },
    {
      "id": 21534,
      "label": "central nervous system infectious disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001456",
          "GARD:0025438",
          "ICD9:349.89",
          "MEDGEN:1684837",
          "MESH:D002494",
          "NCIT:C27582",
          "SCTID:128117002",
          "UMLS:C4759823"
        ],
        "synonyms": [
          "central nervous system infectious disease",
          "central nervous system infectious disorder",
          "infectious disease of central nervous system",
          "central nervous system infection",
          "infections, central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An infectious process that affects the brain and/or spinal cord. Representative examples include encephalitis, poliomyelitis, arachnoiditis, and meningitis."
      },
      "child_count": 24,
      "reference_id": "MONDO:0024619"
    },
    {
      "id": 25145,
      "label": "postinfectious cerebellitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022502",
          "MEDGEN:1843009",
          "Orphanet:624244",
          "UMLS:C5575321"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0850107"
    }
  ],
  "roots": [
    {
      "id": 6799,
      "label": "nervous system disorder"
    },
    {
      "id": 7200,
      "label": "infectious disease"
    }
  ]
}