{
  "id": 19722,
  "label": "postinfectious encephalitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020068",
  "properties": {
    "xrefs": [
      "DOID:10993",
      "GARD:0025152",
      "ICD9:323.6",
      "MEDGEN:581376",
      "MedDRA:10057235",
      "Orphanet:98253",
      "SCTID:192727001",
      "UMLS:C0393459"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 19721,
      "label": "infectious encephalitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19673,
        21534
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025151",
          "ICD9:049.8",
          "ICD9:323.4",
          "MEDGEN:108917",
          "MESH:D000069544",
          "NCIT:C79550",
          "SCTID:312215006",
          "UMLS:C0596773"
        ],
        "synonyms": [
          "encephalitis infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An acute infectious process that affects the brain tissue. It is usually caused by viruses and less often by bacteria, parasites, and fungi."
      },
      "child_count": 20,
      "reference_id": "MONDO:0020067"
    },
    {
      "id": 20718,
      "label": "post-infectious disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:B90-B94",
          "ICD9:139.8",
          "MEDGEN:688819",
          "SCTID:123976001",
          "UMLS:C1264603"
        ],
        "synonyms": [
          "sequela of infectious disorder"
        ],
        "definition": "A disorder that follows infection but is distinct from the infection itself and its usual manifestations."
      },
      "child_count": 14,
      "reference_id": "MONDO:0021669"
    }
  ],
  "children": [
    {
      "id": 16391,
      "label": "limbic encephalitis with LGI1 antibodies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19722
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0013406",
          "MEDGEN:1645969",
          "Orphanet:163908",
          "SCTID:763794005",
          "UMLS:C4706583"
        ],
        "synonyms": [
          "limbic encephalitis with leucine-rich glioma-inactivated 1 antibodies"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Limbic encephalitis with LGI1 antibodies is a rare neuroimmunological disorder characterized by the onset of cognitive decline, psychiatric disturbances and seizures (distinctively faciobrachial dystonic seizures) in association with detection of LGI1 antibodies in serum or cerebrospinal fluid. Patients may present with confusion, hallucinations, vocalization, paranoia, tangentiality, aggressive outbursts and/or spatial disorientation, as well as obstinate hyponatremia. It is most often non-paraneoplastic, however comorbid tumors, such as small cell lung cancer and thymoma, have been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015592"
    },
    {
      "id": 16661,
      "label": "Rasmussen subacute encephalitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19722,
        25079
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018752",
          "ICD9:323.9",
          "MEDGEN:418934",
          "MESH:C535291",
          "NANDO:1200598",
          "NANDO:2100246",
          "NANDO:2200900",
          "NCIT:C125384",
          "NORD:1649",
          "Orphanet:1929",
          "SCTID:230191005",
          "UMLS:C2930868"
        ],
        "synonyms": [
          "CFE",
          "Rasmussen Encephalitis",
          "Rasmussen encephalitis",
          "Rasmussen syndrome",
          "Rasmussen’s encephalitis",
          "Rasmussen’s syndrome",
          "chronic focal encephalitis",
          "RE"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare, progressive chronic inflammation of a single cerebral hemisphere that usually affects children. It is characterized by severe seizures, loss of motor skills and speech, hemiparesis, and dementia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016019"
    },
    {
      "id": 19077,
      "label": "Bickerstaff brainstem encephalitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19722
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018944",
          "ICD9:323.81",
          "MEDGEN:743311",
          "NANDO:1200551",
          "Orphanet:79138",
          "SCTID:427086003",
          "UMLS:C1960543",
          "icd11.foundation:163316971"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Bickerstaff's brainstem encephalitis (BBE) is a rare post-infectious neurological disease characterized by the association of external ophthalmoplegia, ataxia, lower limb arreflexia, extensor plantar response and disturbance of consciousness (drowsiness, stupor or coma)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019208"
    },
    {
      "id": 19214,
      "label": "acute disseminated encephalomyelitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4626,
        19722
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:639",
          "EFO:0007130",
          "GARD:0008639",
          "ICD9:136.9",
          "MEDGEN:4033",
          "MESH:D004673",
          "NCIT:C34578",
          "NORD:727",
          "Orphanet:83597",
          "SCTID:83942000",
          "UMLS:C0014059",
          "icd11.foundation:1390433308"
        ],
        "synonyms": [
          "ADEM",
          "acute disseminated encephalitis",
          "acute disseminated encephalomyelitis",
          "post-infectious encephalomyelitis",
          "ADE"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Acute disseminated encephalomyelitis (ADEM) is a demyelinating disorder of the central nervous system."
      },
      "child_count": 6,
      "reference_id": "MONDO:0019383"
    },
    {
      "id": 19215,
      "label": "encephalitis lethargica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7600,
        19722,
        20335
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5225",
          "GARD:0006332",
          "ICD9:049.8",
          "MEDGEN:4028",
          "MedDRA:10052369",
          "NCIT:C26761",
          "NCIT:C34576",
          "Orphanet:83600",
          "SCTID:186499007",
          "UMLS:C0014040",
          "icd11.foundation:1777779617"
        ],
        "synonyms": [
          "Von Economo encephalitis",
          "encephalitis lethargica",
          "epidemic encephalitis",
          "lethargic encephalitis",
          "von Economo's disease",
          "Von Economo’s disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A form of encephalitis, the etiology of which is uncertain, that is characterized by lethargy and headache."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019384"
    },
    {
      "id": 19216,
      "label": "steroid-responsive encephalopathy associated with autoimmune thyroiditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19722,
        20055
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0008570",
          "MEDGEN:98280",
          "MESH:C535841",
          "Orphanet:83601",
          "UMLS:C0393639"
        ],
        "synonyms": [
          "steroid-responsive encephalopathy associated with thyroid disease",
          "SREAT",
          "Hashimoto encephalitis",
          "Hashimoto's encephalitis",
          "Hashimoto's encephalopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a rare, acquired, neurological disease characterized by encephalopathy associated with elevated antithyroid antibodies, in the absence of other causes. Clinical presentation varies from minor cognitive impairment to status epilepticus and coma, and frequently includes seizures, confusion, speech disorder, memory impairment, ataxia and psychiatric manifestations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019385"
    },
    {
      "id": 20062,
      "label": "rubella encephalitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19722,
        20721
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025196",
          "ICD10CM:B06.01",
          "MEDGEN:536765",
          "SCTID:192689006",
          "UMLS:C0238099"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0020648"
    }
  ],
  "roots": [
    {
      "id": 19721,
      "label": "infectious encephalitis"
    },
    {
      "id": 20718,
      "label": "post-infectious disorder"
    }
  ]
}