{
  "id": 19728,
  "label": "myelodysplastic/myeloproliferative disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020077",
  "properties": {
    "xrefs": [
      "GARD:0009351",
      "MESH:D054437",
      "Orphanet:98275"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Clonal myeloid disorders that possess both dysplastic and proliferative features but are not properly classified as either MYELODYSPLASTIC SYNDROMES or MYELOPROLIFERATIVE disorderS."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 16513,
      "label": "myeloid hemopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020130",
          "MEDGEN:1842523",
          "Orphanet:171895",
          "UMLS:C5680514"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0015756"
    }
  ],
  "children": [
    {
      "id": 6439,
      "label": "atypical chronic myeloid leukemia, BCR-ABL1 negative",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6429,
        7847,
        19728
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060597",
          "DOID:8747",
          "GARD:0019583",
          "ICDO:9876/3",
          "MEDGEN:266233",
          "MedDRA:10054651",
          "NCIT:C3519",
          "Orphanet:98824",
          "SCTID:277589003",
          "UMLS:C1292772",
          "icd11.foundation:331838766"
        ],
        "synonyms": [
          "aCML",
          "atypical CML",
          "atypical chronic myeloid leukaemia",
          "atypical chronic myeloid leukemia",
          "atypical chronic myeloid leukemia, BCR-ABL1 Negative",
          "subacute granulocytic leukaemia",
          "subacute granulocytic leukemia",
          "subacute myelogenous leukaemia",
          "subacute myelogenous leukemia",
          "subacute myeloid leukaemia",
          "subacute myeloid leukemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A myelodysplastic/myeloproliferative neoplasm characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a Philadelphia chromosome or the BCR/ABL fusion gene. (WHO, 2001)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0004653"
    },
    {
      "id": 19790,
      "label": "chronic myelomonocytic leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3274,
        7847,
        19728
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080188",
          "EFO:1001779",
          "GARD:0008225",
          "ICD10CM:C93.1",
          "ICDO:9945/3",
          "MEDGEN:44125",
          "MESH:D015477",
          "MedDRA:10009018",
          "NANDO:2200014",
          "NCIT:C3178",
          "ONCOTREE:CMML",
          "Orphanet:98823",
          "SCTID:127225006",
          "UMLS:C0023480",
          "icd11.foundation:2073226578"
        ],
        "synonyms": [
          "CMML",
          "chronic myelomonocytic leukaemia (CMML)",
          "chronic myelomonocytic leukemia",
          "chronic myelomonocytic leukemia (CMML)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A myelodysplastic/myeloproliferative neoplasm which is characterized by persistent monocytosis, absence of a Philadelphia chromosome and BCR/ABL fusion gene, fewer than 20 percent blasts in the bone marrow and blood, myelodysplasia, and absence of PDGFRA or PDGFRB rearrangement."
      },
      "child_count": 3,
      "reference_id": "MONDO:0020311"
    }
  ],
  "roots": [
    {
      "id": 16513,
      "label": "myeloid hemopathy"
    }
  ]
}