{
  "id": 19729,
  "label": "dendritic cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020082",
  "properties": {
    "xrefs": [
      "GARD:0008317",
      "MEDGEN:1842732",
      "Orphanet:98289",
      "SCTID:737223000",
      "UMLS:C5681852"
    ],
    "synonyms": [
      "dendritic cell sarcoma, NOS",
      "dendritic cell sarcoma, Not otherwise specified",
      "dendritic cell tumor, NOS",
      "dendritic cell tumor, not otherwise specified",
      "dendritic cell neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A dendritic cell tumor develops from the cells of the immune system. This condition typically begins in the lymph system and may spread to nearby organs or distant parts of the body (metastasize). The symptoms and severity of the condition depend on the subtype and location of the tumor."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7797,
      "label": "histiocytic and dendritic cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16514,
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5621",
          "EFO:1000297",
          "GARD:0019441",
          "MEDGEN:714988",
          "NCIT:C9294",
          "Orphanet:98287",
          "UMLS:C1292762"
        ],
        "synonyms": [
          "histiocytic and Dendritic cell neoplasms",
          "histiocytic and Dendritic cell tumors",
          "histiocytic and Dendritic cell tumours",
          "histiocytic and dendritic cell neoplasm",
          "histiocytic and dendritic cell",
          "histiocytic and dendritic cell cancer",
          "histiocytic and dendritic cell tumor",
          "histiocytic and dendritic cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Rare tumors that affect the hematopoietic and lymphoid tissues. The cells of origin are the histiocytes and accessory cells. They can occur at any age and show no significant variations in geographical distribution. This category includes the histiocytic sarcoma, Langerhans cell histiocytosis, Langerhans cell sarcoma, interdigitading dendritic cell sarcoma/tumor, follicular dendritic cell sarcoma/tumor, and dendritic cell sarcoma, not otherwise specified. (WHO, 2001)"
      },
      "child_count": 6,
      "reference_id": "MONDO:0006247"
    }
  ],
  "children": [
    {
      "id": 6193,
      "label": "dendritic cell sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3028,
        6569,
        6816,
        19729
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7849",
          "GARD:0019082",
          "MEDGEN:226984",
          "NCIT:C27260",
          "ONCOTREE:DCS",
          "Orphanet:86903",
          "SCTID:446643000",
          "UMLS:C1301364"
        ],
        "synonyms": [
          "dendritic cell sarcoma",
          "sarcoma of dendritic cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A sarcoma that involves the dendritic cell."
      },
      "child_count": 12,
      "reference_id": "MONDO:0004380"
    },
    {
      "id": 11176,
      "label": "reticulum cell sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3023,
        6816,
        19729
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8538",
          "EFO:0005287",
          "GARD:0016765",
          "ICD9:200.0",
          "ICD9:200.00",
          "ICD9:200.7",
          "MEDGEN:44224",
          "MedDRA:10038804",
          "NCIT:C27824",
          "OMIM:267730",
          "Orphanet:86900",
          "SCTID:373168002",
          "UMLS:C0024302"
        ],
        "synonyms": [
          "Reticulum cell sarcoma",
          "interdigitating cell sarcoma",
          "large-cell Lymphomas",
          "reticular cell sarcoma",
          "reticulosarcoma",
          "reticulum cell sarcoma",
          "sarcoma of reticular cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An antiquated term that refers to a non-Hodgkin lymphoma composed of diffuse infiltrates of large, often anaplastic lymphocytes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009975"
    },
    {
      "id": 18407,
      "label": "Langerhans cell histiocytosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4688,
        6569,
        19729,
        21541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2571",
          "EFO:1000318",
          "GARD:0006858",
          "ICD9:202.5",
          "ICD9:277.89",
          "ICDO:9751/1",
          "ICDO:9751/3",
          "ICDO:9752/1",
          "ICDO:9753/1",
          "ICDO:9754/3",
          "MEDGEN:5568",
          "MedDRA:10069698",
          "NANDO:2200031",
          "NCIT:C3107",
          "NORD:1348",
          "OMIM:604856",
          "ONCOTREE:LCH",
          "Orphanet:389",
          "SCTID:65399007",
          "UMLS:C0019621",
          "icd11.foundation:1388720498",
          "icd11.foundation:216625985"
        ],
        "synonyms": [
          "LCH",
          "Langerhans cell granulomatosis",
          "Langerhans cell histiocytosis",
          "Langerhans cell histiocytosis, NOS",
          "Langerhans cell histiocytosis, Not otherwise specified",
          "histiocytosis X",
          "Langerhans-cell histiocytosis",
          "Lch"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues."
      },
      "child_count": 32,
      "reference_id": "MONDO:0018310"
    }
  ],
  "roots": [
    {
      "id": 7797,
      "label": "histiocytic and dendritic cell neoplasm"
    }
  ]
}