{
  "id": 19750,
  "label": "acquired motor neuron disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020129",
  "properties": {
    "xrefs": [
      "GARD:0019479",
      "MEDGEN:1842733",
      "Orphanet:98506",
      "UMLS:C5680367"
    ],
    "synonyms": [
      "acquired anterior horn cell disease",
      "acquired motor neuron disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An instance of motor neuron disease that is acquired during the lifetime of the individual."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 19749,
      "label": "motor neuron disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7208,
        18957
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:231",
          "EFO:0003782",
          "GARD:0019477",
          "ICD10CM:G12.2",
          "ICD9:335.2",
          "ICD9:335.8",
          "ICD9:335.9",
          "MEDGEN:38785",
          "MESH:D016472",
          "MedDRA:10028003",
          "Orphanet:98503",
          "SCTID:37340000",
          "UMLS:C0085084",
          "icd11.foundation:661720689"
        ],
        "synonyms": [
          "anterior horn cell disease",
          "disease of motor neuron",
          "disease or disorder of motor neuron",
          "disorder of motor neuron",
          "motor neuron disease",
          "motor neuron disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Neurological disease involving the motor neuron."
      },
      "child_count": 8,
      "reference_id": "MONDO:0020128"
    }
  ],
  "children": [
    {
      "id": 12344,
      "label": "monomelic amyotrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19750
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001989",
          "GARD:0009697",
          "MEDGEN:356265",
          "MESH:C538253",
          "MedDRA:10069681",
          "OMIM:602440",
          "Orphanet:65684",
          "UMLS:C1865384",
          "icd11.foundation:2090347823"
        ],
        "synonyms": [
          "Hirayama disease",
          "JMADUE",
          "benign focal amyotrophy",
          "juvenile muscular atrophy of distal upper extremity",
          "juvenile muscular atrophy of the distal upper limb",
          "amyotrophy, monomelic",
          "spinal muscular atrophy juvenile nonprogressive",
          "spinal muscular atrophy, juvenile, nonprogressive"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Monomelic amyotrophy (MA) is a rare benign lower motor neuron disorder characterized by muscular weakness and wasting in the distal upper extremities during adolescence followed by a spontaneous halt in progression and a stabilization of symptoms."
      },
      "child_count": 1,
      "reference_id": "MONDO:0011224"
    },
    {
      "id": 17684,
      "label": "poliomyelitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4629,
        5143,
        19750,
        20092,
        21351,
        21533
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4953",
          "EFO:0007450",
          "GARD:0007413",
          "ICD9:045",
          "ICD9:045.9",
          "ICD9:045.90",
          "ICD9:045.92",
          "MEDGEN:18545",
          "MESH:D011051",
          "MedDRA:10036012",
          "NCIT:C35550",
          "Orphanet:2912",
          "SCTID:398102009",
          "UMLS:C0032371",
          "icd11.foundation:588527933"
        ],
        "synonyms": [
          "Polia",
          "acute poliomyelitis",
          "polio",
          "poliomyelitis",
          "infantile paralysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine."
      },
      "child_count": 18,
      "reference_id": "MONDO:0017373"
    },
    {
      "id": 22922,
      "label": "Mills syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19750
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019250",
          "MEDGEN:1682801",
          "Orphanet:94091",
          "UMLS:C5191669"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare, acquired motor neuron disease characterized by a slowly progressive, unilateral, ascending or descending hemplegia, associated to unilateral or asymmetrical pyramidal signs and no sensory loss. It is a diagnosis of exclusion and contorversy exists regarding whether the presence of bulbar symptoms, sphincter disturbances, fasciculations or cognitive manifestations characterize the disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0035892"
    }
  ],
  "roots": [
    {
      "id": 19749,
      "label": "motor neuron disorder"
    }
  ]
}