{
  "id": 19773,
  "label": "uveitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020283",
  "properties": {
    "xrefs": [
      "DOID:13141",
      "EFO:1001231",
      "GARD:0019549",
      "HP:0000554",
      "MEDGEN:52961",
      "MESH:D014605",
      "MedDRA:10046851",
      "NCIT:C26909",
      "Orphanet:98715",
      "SCTID:128473001",
      "UMLS:C0042164"
    ],
    "synonyms": [
      "inflammation of uvea",
      "uvea inflammation",
      "uveitis",
      "uveitis (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "An inflammatory process affecting a part of or the entire uvea. Causes include inflammatory agents (e.g., herpes simplex, herpes zoster, leptospirosis) and systemic diseases (e.g., inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, ankylosing spondylitis). Patients present with pain and redness in the eye, light sensitivity, and blurred and decreased vision."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 4712,
      "label": "uveal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7019
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3480",
          "MEDGEN:21804",
          "MESH:D014603",
          "NCIT:C26908",
          "SCTID:95678007",
          "UMLS:C0042161"
        ],
        "synonyms": [
          "disease of uvea",
          "disease or disorder of uvea",
          "disorder of uvea",
          "uvea disease",
          "uvea disease or disorder",
          "uveal disease",
          "uveal disorder",
          "uveal tract disease",
          "disorder of uveal tract",
          "uveal diseases"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the uvea. Representative examples include uveitis, chorioretinitis, and uveal melanoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002661"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 6458,
      "label": "chorioretinitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8886",
          "GARD:0006060",
          "HP:0012424",
          "ICD9:363.20",
          "MEDGEN:942",
          "MESH:D002825",
          "NCIT:C110923",
          "SCTID:46627006",
          "UMLS:C0008513"
        ],
        "synonyms": [
          "chorioretinitis",
          "chorioretinitis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Inflammation of the distal posterior uveal tract (choroid) and its structural and vascular attachments to the retina. It is usually caused by infection and though rare, it is clinically significant due to its most serious sequela: loss of vision."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004674"
    },
    {
      "id": 8123,
      "label": "anterior uveitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:1114-9593",
          "DOID:1407",
          "EFO:1000811",
          "HP:0012122",
          "MEDGEN:22595",
          "MESH:D014606",
          "MedDRA:10002709",
          "NCIT:C35109",
          "Orphanet:280886",
          "SCTID:410692006",
          "UMLS:C0042165",
          "icd11.foundation:908233081"
        ],
        "synonyms": [
          "anterior uveitis",
          "anterior uveitis (disease)",
          "iridocyclitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Inflammation of the iris and anterior chamber of the eye."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006651"
    },
    {
      "id": 8254,
      "label": "intermediate uveitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12732",
          "EFO:1000986",
          "GARD:0021065",
          "HP:0012124",
          "MEDGEN:22596",
          "MESH:D015867",
          "MedDRA:10022557",
          "NCIT:C35110",
          "Orphanet:279914",
          "SCTID:314429009",
          "UMLS:C0042166",
          "icd11.foundation:892860325"
        ],
        "synonyms": [
          "IU",
          "intermediate uveitis",
          "intermediate uveitis (disease)",
          "pars planitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Inflammation of the pars plana."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006806"
    },
    {
      "id": 8262,
      "label": "iritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4401,
        19773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1406",
          "EFO:1000997",
          "GARD:0024477",
          "HP:0001101",
          "MEDGEN:7160",
          "MESH:D007500",
          "MedDRA:10022955",
          "NCIT:C50621",
          "SCTID:65074000",
          "UMLS:C0022081"
        ],
        "synonyms": [
          "inflammation of iris",
          "iris inflammation",
          "iritis",
          "iritis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Inflammation of the iris."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006814"
    },
    {
      "id": 8351,
      "label": "posterior uveitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12574",
          "EFO:1001119",
          "GARD:0024501",
          "MEDGEN:22597",
          "MESH:D015866",
          "MedDRA:10036370",
          "SCTID:43363007",
          "UMLS:C0042167"
        ],
        "synonyms": [
          "chorioretinal region inflammation",
          "inflammation of chorioretinal region"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Inflammation of the choroid as well as the retina and vitreous body. Some form of visual disturbance is usually present. The most important characteristics of posterior uveitis are vitreous opacities, choroiditis, and chorioretinitis."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006918"
    },
    {
      "id": 8414,
      "label": "suppurative uveitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13140",
          "GARD:0024513",
          "MEDGEN:22598",
          "MESH:D015829",
          "UMLS:C0042168"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Intraocular infection caused mainly by pus-producing bacteria and rarely by fungi. The infection may be caused by an injury or surgical wound (exogenous) or by endogenous septic emboli in such diseases as bacterial endocarditis or meningococcemia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006990"
    },
    {
      "id": 17589,
      "label": "panuveitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12030",
          "EFO:1001082",
          "GARD:0008577",
          "HP:0012121",
          "ICD10CM:H44.11",
          "ICD9:360.12",
          "MEDGEN:45303",
          "MESH:D015864",
          "MedDRA:10033687",
          "NCIT:C84989",
          "Orphanet:280898",
          "SCTID:75614007",
          "UMLS:C0030343",
          "icd11.foundation:1125547814"
        ],
        "synonyms": [
          "diffuse uveitis",
          "panuveitis",
          "panuveitis (disease)",
          "total uveitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A disorder characterized by inflammation of the entire uvea which includes the iris, ciliary body, and choroid. Causes include systemic infections, sarcoidosis, and cancers."
      },
      "child_count": 4,
      "reference_id": "MONDO:0017255"
    },
    {
      "id": 17591,
      "label": "idiopathic posterior uveitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19773,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021099",
          "MEDGEN:1657160",
          "Orphanet:280917",
          "UMLS:C4751435"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Idiopathic posterior uveitis is a rare, potentially sight-threatening, ocular disease, not attributed to any specific ocular or systemic cause, characterized by focal, multifocal or diffuse non-infectious inflammation in the posterior uvea (i.e. choroiditis, chorioretinitis, retinitis and neuroretinitis). Visual morbidity due to complications (including cystoid macular edema and choroidal neovascularization) has been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017257"
    },
    {
      "id": 22196,
      "label": "autoimmune uveitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3003,
        19773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0040088",
          "GARD:0025675",
          "MEDGEN:1843501",
          "UMLS:C3888523"
        ],
        "synonyms": [
          "autoimmune uveitis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "An autoimmune form of uveitis (disease)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0031012"
    }
  ],
  "roots": [
    {
      "id": 4712,
      "label": "uveal disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}