{
  "id": 19778,
  "label": "congenital pulmonary veins anomaly",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020295",
  "properties": {
    "xrefs": [
      "GARD:0019559",
      "MEDGEN:539575",
      "NCIT:C110942",
      "Orphanet:98729",
      "SCTID:111322000",
      "UMLS:C0265914"
    ],
    "synonyms": [
      "congenital anomaly of pulmonary veins",
      "pulmonary vein abnormality"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Aberrant drainage of one or more of the pulmonary veins which causes the return of oxygen-rich blood to the right atrium."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 7116,
      "label": "congenital heart disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1682",
          "EFO:0005207",
          "ICD9:746.84",
          "ICD9:746.89",
          "ICD9:746.9",
          "MEDGEN:57501",
          "MESH:D006330",
          "NCIT:C95834",
          "SCTID:13213009",
          "UMLS:C0152021",
          "icd11.foundation:2004408087"
        ],
        "synonyms": [
          "heart malformation",
          "congenital anomaly of heart",
          "congenital heart defect",
          "congenital heart defects",
          "Abnormality, heart",
          "abnormalities, heart",
          "defect, congenital heart",
          "defects, congenital heart",
          "heart abnormalities",
          "heart abnormality",
          "heart defect, congenital",
          "heart, malformation Of"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heart disease that is present at birth. Representative examples include atrial septal defect, ventricular septal defect, tetralogy of Fallot, and patent foramen ovale."
      },
      "child_count": 46,
      "reference_id": "MONDO:0005453"
    }
  ],
  "children": [
    {
      "id": 11136,
      "label": "alveolar capillary dysplasia with misalignment of pulmonary veins",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17417,
        19778,
        22225,
        24272
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13042",
          "GARD:0008644",
          "ICD9:747.49",
          "ICD9:747.83",
          "MEDGEN:755478",
          "MESH:C536590",
          "MedDRA:10054726",
          "NCIT:C98809",
          "NORD:759",
          "OMIM:265380",
          "Orphanet:210122",
          "SCTID:447275002",
          "UMLS:C2960310"
        ],
        "synonyms": [
          "ACDMPV",
          "alveolar capillary dysplasia",
          "alveolar capillary dysplasia with misalignment of pulmonary veins",
          "alveolar capillary dysplasia with misalignment of pulmonary vessels",
          "congenital alveolar capillary dysplasia",
          "foetal circulation",
          "alveolar capillary dysplasia with misalignment of pulmonary veins and Other congenital anomalies",
          "alveolar capillary dysplasia with misalignment of pulmonary veins and other congenital anomalies",
          "alveolar capillary dysplasia with pulmonary venous misalignment",
          "familial persistent pulmonary hypertension of the newborn",
          "persistent fetal circulation",
          "persistent foetal circulation",
          "persistent foetal circulation syndrome",
          "persistent pulmonary hypertension of the newborn",
          "pulmonary hypertension, familial persistent of the newborn"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare and fatal developmental lung disease characterized by respiratory distress in neonates due to refractory hypoxemia and severe pulmonary arterial hypertension."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009934"
    },
    {
      "id": 17943,
      "label": "congenital pulmonary venous return anomaly",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0004599",
          "MEDGEN:539577",
          "Orphanet:3090",
          "UMLS:C0265916"
        ],
        "synonyms": [
          "congenital pulmonary venous connection anomaly",
          "APVR",
          "TAPVR",
          "TAPVR1",
          "anomalous pulmonary venous return",
          "pulmonary venous return anomaly",
          "scimitar anomaly",
          "scimitar syndrome",
          "total anomalous pulmonary venous return"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Congenital pulmonary venous return anomaly is a cardiac malformation where some or all of the pulmonary veins drain into the right atrium or the systemic veins, with or without the presence of pulmonary venous obstruction, leading to various manifestations such as fatigue, exertional dyspnea, pulmonary arterial hypertension, cyanosis and progressive congestive heart failure. The two main subtypes are congenital partial pulmonary venous return anomaly (PAPVC), where one or a few of the pulmonary veins are anomalous, and congenital total pulmonary venous return anomaly (TAPVC), where all of the pulmonary veins are anomalous."
      },
      "child_count": 3,
      "reference_id": "MONDO:0017705"
    },
    {
      "id": 23829,
      "label": "congenital alveolar dysplasia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026035",
          "MEDGEN:20539",
          "UMLS:C0035220"
        ],
        "synonyms": [
          "CAD"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A congenital alveolar dysplasia characterized anatomically by a defective and hypoplastic development of pulmonary alveoli that is commonly associated with atelectasis and can be responsible for atelectasis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0100077"
    },
    {
      "id": 24386,
      "label": "alveolar capillary dysplasia without misalignment of pulmonary veins",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026296"
        ],
        "synonyms": [
          "ACD without misalignment"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A rare form of interstitial and vascular lung disease that presents as severe pulmonary hypertension and refractory hypoxemia early in life that is characterized by a lack of misalignment of the pulmonary veins."
      },
      "child_count": 0,
      "reference_id": "MONDO:0600014"
    }
  ],
  "roots": [
    {
      "id": 7116,
      "label": "congenital heart disease"
    }
  ]
}