{
  "id": 19779,
  "label": "congenital arteriovenous fistula",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020296",
  "properties": {
    "xrefs": [
      "GARD:0019560",
      "MEDGEN:137676",
      "MESH:D001164",
      "MedDRA:10003226",
      "NCIT:C35377",
      "Orphanet:98731",
      "SCTID:234148007",
      "UMLS:C0332965"
    ],
    "synonyms": [
      "congenital arteriovenous shunt"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A congenital vascular disorder characterized byan abnormal connection between an artery and a vein, appearing as varicose veins with port wine discoloration, leading to a bypass of the capillary bed. Signs and symptoms include palpable continuous thrill in the dilated vessels, continuous machinery murmur with systolic accentuation, collapsing arterial pulse, Nicoladoni Branham sign, as well as local gigantism and hot ulcers due to hypoxia, among others."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 21294,
      "label": "congenital anomaly of cardiovascular system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:747.89",
          "ICD9:747.9",
          "MEDGEN:777113",
          "NCIT:C35729",
          "SCTID:9904008",
          "UMLS:C3665496"
        ],
        "synonyms": [
          "cardiovascular system development disease",
          "congenital Abnormality of the circulatory system",
          "congenital anomaly of cardiovascular system",
          "congenital cardiovascular Abnormality",
          "congenital cardiovascular anomaly",
          "disorder of cardiovascular system development",
          "congenital cardiovascular disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease that has its basis in the disruption of cardiovascular system development."
      },
      "child_count": 10,
      "reference_id": "MONDO:0024239"
    }
  ],
  "children": [
    {
      "id": 16707,
      "label": "congenital systemic arteriovenous fistula",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19779
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018758",
          "MEDGEN:1679454",
          "Orphanet:2039",
          "UMLS:C5191839"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A rare, potentially life-threatening, vascular disease characterized by a direct communication between an artery and a vein, without the interposition of the capillary bed, ocurring in the systemic circulation (mainly the cranium, liver, lungs, extremities, and vessels in or near the thoracic wall). Manifestations are variable depending on size and extent of the fistula, the involved blood vessels and the precise location of the collaterals and may include systolic or continuous murmur over the affected organ, tachycardia, increased stroke volume, cardiomegaly and increased pulmonary vascular markings."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016078"
    },
    {
      "id": 26262,
      "label": "congenital intrahepatic arterioportal fistula",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19779
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:694228"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0979271"
    }
  ],
  "roots": [
    {
      "id": 21294,
      "label": "congenital anomaly of cardiovascular system"
    }
  ]
}