{
  "id": 19802,
  "label": "aggressive systemic mastocytosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020333",
  "properties": {
    "xrefs": [
      "DOID:4798",
      "GARD:0019597",
      "ICD10CM:C96.21",
      "ICDO:9741/3",
      "MEDGEN:206813",
      "MedDRA:10056453",
      "NCIT:C9285",
      "ONCOTREE:ASM",
      "Orphanet:98850",
      "SCTID:716655008",
      "UMLS:C1112486",
      "icd11.foundation:870477963"
    ],
    "synonyms": [
      "ASM",
      "aggressive systemic mastocytosis (morphologic abnormality)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Aggressive systemic mastocytosis (ASM) is a severe and rare form of systemic mastocytosis (SM) characterized by considerable infiltration of mast cells in different tissues."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 17076,
      "label": "systemic mastocytosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        9280
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:349",
          "GARD:0008616",
          "ICD10CM:D47.02",
          "MEDGEN:67436",
          "MedDRA:10042949",
          "NCIT:C9235",
          "ONCOTREE:SM",
          "Orphanet:2467",
          "SCTID:397016004",
          "UMLS:C0221013",
          "icd11.foundation:1144812971"
        ],
        "synonyms": [
          "Mast cell disease",
          "systemic mastocytosis",
          "systemic tissue Mast cell disease",
          "systemic tissue mast cell disease",
          "Aggressive systemic mastocytosis",
          "SM",
          "systemic mast cell disease",
          "systemic mastocytosis with associated hemotologic non-mast cell lineage disease (SM-AHNMD)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Systemic mastocytosis (SM) comprises a heterogeneous group of rare acquired and chronic hematological malignancies that are related to an abnormal proliferation of mast cells in tissue, including bone marrow, with or without skin involvement."
      },
      "child_count": 5,
      "reference_id": "MONDO:0016586"
    }
  ],
  "children": [
    {
      "id": 16370,
      "label": "lymphoadenopathic mastocytosis with eosinophilia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19802
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:158793",
          "icd11.foundation:809306056"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0015559"
    }
  ],
  "roots": [
    {
      "id": 17076,
      "label": "systemic mastocytosis"
    }
  ]
}