{
  "id": 19831,
  "label": "Cogan-Reese syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020370",
  "properties": {
    "xrefs": [
      "DOID:0060217",
      "GARD:0006125",
      "MEDGEN:218910",
      "MedDRA:10059200",
      "NCIT:C84644",
      "Orphanet:98980",
      "SCTID:404633004",
      "UMLS:C1168173",
      "icd11.foundation:1968906450"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "Cogan-Reese syndrome is a clinical variant of iridocorneal endothelial (ICE) syndrome characterized by variable iris atrophy, pigmented and pedunculated nodules on the iris and corneal abonormalities. Secondary glaucoma is also a common complication of the disease."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18905,
      "label": "iridocorneal endothelial syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000060",
          "MEDGEN:242751",
          "MESH:D057129",
          "MedDRA:10053678",
          "NCIT:C84792",
          "Orphanet:64734",
          "SCTID:129623003",
          "UMLS:C1096100",
          "icd11.foundation:265074385"
        ],
        "synonyms": [
          "ICE syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Iridocorneal endothelial (ICE) syndrome describes a group of progressive corneal proliferative endotheliopathies comprised of Chandler syndrome, Cogan-Reese syndrome and essential iris atrophy, affecting mainly young adult females and characterized by iris holes and atrophy, papillary distortion, anterior synechiae, corneal edema and often with secondary glaucoma and corneal decompensation as complications"
      },
      "child_count": 3,
      "reference_id": "MONDO:0018988"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18905,
      "label": "iridocorneal endothelial syndrome"
    }
  ]
}