{
  "id": 19872,
  "label": "encircling double aortic arch",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020413",
  "properties": {
    "xrefs": [
      "GARD:0019635",
      "MEDGEN:1641325",
      "NANDO:2200290",
      "Orphanet:99075",
      "SCTID:764521002",
      "UMLS:C4706940"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Encircling double aortic arch is a very rare congenital anomaly of the great arteries characterized by the presence of two aortic arches (right and left) which encircle and compress the trachea and esophagus, resulting in various respiratory and gastrointestinal symptoms (e.g. harsh breathing, stridor, dyspnea, cyanotic and choking episodes, chronic cough, recurrent respiratory tract infections, dysphagia and reflux). Esophageal atresia and tracheoesophageal fistula have also been reported. It usually occurs isolated, but, on occasion, may be associated with other congenital heart anomalies and chromosomal aberations."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16127,
      "label": "aortic arch defects",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19777
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000741",
          "MEDGEN:1842770",
          "Orphanet:1132",
          "UMLS:C5680872"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Congenital abnormalities of the aortic arch result from aberrant development of one or more components of the embyronic pharangeal arch system. Any component of this system can regress or persist abnormally, resulting in an extensive array of aortic arch anomalies. Clinically, they are classified by those that cause (or are likely to cause) physiolgogical abnormalities and those that do not. Physiologic abnormalities include tracheobronchial compression, esophageeal compression, and abnormal blood flow patteren."
      },
      "child_count": 7,
      "reference_id": "MONDO:0015236"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16127,
      "label": "aortic arch defects"
    }
  ]
}