{
  "id": 19874,
  "label": "Kommerell diverticulum",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020415",
  "properties": {
    "xrefs": [
      "GARD:0019637",
      "MEDGEN:488820",
      "Orphanet:99077",
      "SCTID:74561007",
      "UMLS:C0265885"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Kommerell diverticulum (KD) is a developmental anomaly of the aortic arch characterized by a diverticulum at the proximal descending aorta of left or right arch configuration that gives rise to an aberrant subclavian artery. KD is primarily asymptomatic but may become symptomatic secondary to dilatation of KD, atheroma and fibrotic changes in paratracheal or paraesophageal tissue, presenting with signs of tracheal compression (more common in children), esophageal compression (dysphagia lusoria; more common in patients with a right sided aortic arch), chest pain, or blood pressure difference in the upper limbs. KD may also predispose toward aortic dissection or rupture."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16127,
      "label": "aortic arch defects",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19777
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000741",
          "MEDGEN:1842770",
          "Orphanet:1132",
          "UMLS:C5680872"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Congenital abnormalities of the aortic arch result from aberrant development of one or more components of the embyronic pharangeal arch system. Any component of this system can regress or persist abnormally, resulting in an extensive array of aortic arch anomalies. Clinically, they are classified by those that cause (or are likely to cause) physiolgogical abnormalities and those that do not. Physiologic abnormalities include tracheobronchial compression, esophageeal compression, and abnormal blood flow patteren."
      },
      "child_count": 7,
      "reference_id": "MONDO:0015236"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16127,
      "label": "aortic arch defects"
    }
  ]
}