{
  "id": 19898,
  "label": "patent foramen ovale",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020439",
  "properties": {
    "xrefs": [
      "DOID:13620",
      "HP:0001655",
      "MEDGEN:8891",
      "MESH:D054092",
      "MedDRA:10016982",
      "NANDO:2200266",
      "NCIT:C34619",
      "Orphanet:99108",
      "UMLS:C0016522",
      "icd11.foundation:1618980674"
    ],
    "synonyms": [
      "ostium secundum type atrial septal defect",
      "patent foramen ovale",
      "patent foramen ovale (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A persistent opening in the atrial septum after birth. While a normal part of fetal circulation, the foramen ovale should close once the newborn begins breathing and the pressure in the left atrium exceeds that of the right atrium. While a PFO is generally asymptomatic, it can lead to the passage of clots from the venous circulation into the artierial circulation, resulting in paradoxical emboli, and possible strokes."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 8134,
      "label": "atrial septal defect",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4221,
        24272
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1882",
          "EFO:1000825",
          "ICD10CM:Q21.1",
          "MEDGEN:6753",
          "MESH:D006344",
          "MedDRA:10003664",
          "MedDRA:10019308",
          "MedDRA:10068864",
          "NANDO:2100085",
          "NCIT:C84473",
          "NORD:820",
          "OMIMPS:108800",
          "Orphanet:1478",
          "SCTID:253366007",
          "UMLS:C0018817",
          "icd11.foundation:1285985084"
        ],
        "synonyms": [
          "ASD",
          "Atrial Septal Defects",
          "atrial septal defect",
          "atrial septum defect",
          "auricular septal defect",
          "congenital atrial septal defect",
          "interatrial septal defect",
          "interauricular communication",
          "interatrial communication"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Interauricular communication is a congenital malformation characterized by a communication between the atrial chambers of the heart."
      },
      "child_count": 30,
      "reference_id": "MONDO:0006664"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 8134,
      "label": "atrial septal defect"
    }
  ]
}