{
  "id": 19919,
  "label": "acquired von willebrand syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020460",
  "properties": {
    "xrefs": [
      "DOID:0111146",
      "GARD:0005573",
      "MEDGEN:543999",
      "MedDRA:10069495",
      "NANDO:1200899",
      "Orphanet:99147",
      "PMID:28028990",
      "SCTID:234451005",
      "UMLS:C0272362"
    ],
    "synonyms": [
      "acquired von Willebrand disease",
      "acquired von Willebrand disease (hereditary or acquired)",
      "acquired von willebrand disease",
      "Willebrand disease, acquired"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Acquired von Willebrand syndrome (AVWS) is a bleeding disorder marked by the same biological anomalies as those seen in hereditary von Willebrand disease (VWD) but which occurs in association with another underlying pathology, generally in elderly patients without any personal or family history of bleeding anomalies."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4360,
      "label": "hemorrhagic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2213",
          "ICD9:287.9",
          "MEDGEN:6799",
          "MESH:D006474",
          "NCIT:C115221",
          "UMLS:C0019087"
        ],
        "synonyms": [
          "bleeding diathesis",
          "bleeding disorder",
          "bleeding predisposition",
          "bleeding tendency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (blood coagulation disorders) or another abnormality causing a structural flaw in the blood vessels (hemostatic disorders)."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002243"
    },
    {
      "id": 20034,
      "label": "acquired coagulation factor deficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4359
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025183",
          "ICD10CM:D68.4",
          "MEDGEN:98",
          "NANDO:1200896",
          "NCIT:C34347",
          "SCTID:25904003",
          "UMLS:C0001169"
        ],
        "synonyms": [
          "acquired coagulation factor deficiency",
          "acquired coagulation protein disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Deficiency of a coagulation factor that is not caused by genetic alterations. Causes include vitamin K deficiency, amyloidosis, and severe liver disease."
      },
      "child_count": 6,
      "reference_id": "MONDO:0020599"
    },
    {
      "id": 21519,
      "label": "von Willebrand disease (hereditary or acquired)",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4359
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025434",
          "ICD10CM:D68.0",
          "ICD9:286.4",
          "MEDGEN:22686",
          "MESH:D014842",
          "NANDO:2200682",
          "NCIT:C68677",
          "SCTID:128105004",
          "UMLS:C0042974"
        ],
        "synonyms": [
          "VWD",
          "Von Willebrand Disease",
          "von Willebrand disorder",
          "von Willebrand's disease",
          "von Willebrand disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Hereditary or acquired coagulation disorder characterized by a qualitative or quantitative deficiency of the von Willebrand factor. The latter plays an important role in platelet adhesion. Signs and symptoms include bruises, nose bleeding, gum bleeding following a dental procedure, heavy menstrual bleeding, and gastrointestinal bleeding."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024574"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4360,
      "label": "hemorrhagic disease"
    },
    {
      "id": 20034,
      "label": "acquired coagulation factor deficiency"
    },
    {
      "id": 21519,
      "label": "von Willebrand disease (hereditary or acquired)"
    }
  ]
}