{
  "id": 19982,
  "label": "malignant dysgerminomatous germ cell tumor of ovary",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020538",
  "properties": {
    "xrefs": [
      "GARD:0019705",
      "Orphanet:99912"
    ],
    "synonyms": [
      "dysgerminomatous germ cell cancer of ovary",
      "dysgerminomatous germ cell cancer of the ovary",
      "malignant ovarian dysgerminoma",
      "malignant dysgerminomatous germ cell tumor of the ovary",
      "malignant dysgerminomatous germ cell tumour of the ovary"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Malignant dysgerminomatous germ cell tumor of ovary is the most common form of malignant germ cell tumor of ovary, arising from germ cells in the ovary, usually presenting during adolescence with pelvic mass, fever, vaginal bleeding, and acute abdomen and is characterized by bilaterality (around 10% of cases), association with dysgenetic gonads (5 to 10% of cases), elevated serum lactate dehydrogenase (LDH) and human chorionic gonadotrophin (hCG) (in the presence of syncitiotrophoblasts). Malignant dysgerminomatous germ cell tumor of ovary responds well to chemotherapy, potentially sparing patients from infertility and early mortality."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18315,
      "label": "malignant germ cell tumor of ovary",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7832,
        12476,
        18335,
        18448
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2155",
          "GARD:0009330",
          "MEDGEN:87544",
          "NCIT:C4514",
          "Orphanet:35807",
          "SCTID:254869000",
          "UMLS:C0346180"
        ],
        "synonyms": [
          "MOGCT",
          "malignant germ cell neoplasm of ovary",
          "malignant germ cell neoplasm of the ovary",
          "malignant germ cell tumor of ovary",
          "malignant germ cell tumor of the ovary",
          "malignant germ cell tumour of the ovary",
          "malignant ovarian germ cell neoplasm",
          "malignant ovarian germ cell tumor",
          "malignant ovarian germ cell tumour",
          "ovarian germ cell cancer",
          "ovary malignant germ cell tumor",
          "ovary malignant germ cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Malignant germ cell tumor of ovary is a rare ovarian cancer arising from germ cells in the ovary, frequently unilateral at diagnosis which characteristically presents during adolescence with pelvic mass, fever, vaginal bleeding and acute abdomen."
      },
      "child_count": 16,
      "reference_id": "MONDO:0018171"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18315,
      "label": "malignant germ cell tumor of ovary"
    }
  ]
}