{
  "id": 19984,
  "label": "ovarian gynandroblastoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020540",
  "properties": {
    "xrefs": [
      "GARD:0009665",
      "ICDO:8632/1",
      "MEDGEN:83412",
      "MESH:C538459",
      "NCIT:C3072",
      "Orphanet:99914",
      "SCTID:254867003",
      "UMLS:C0346178"
    ],
    "synonyms": [
      "Gynandroblastoma of ovary",
      "Gynandroblastoma of the ovary",
      "Gynandroblastoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A rare neoplasm arising from the ovary. Although it may occur at any age, it is more often seen in young females. Morphologically, it is characterized by a mixture of two cellular populations: well differentiated Sertoli cells and granulosa cells, with the latter constituting at least ten percent of the neoplasm. The vast majority of cases are stage I lesions at presentation and produce either estrogenic or androgenic manifestations. Although it may present as a massive ovarian tumor, it usually follows a benign clinical course. Very rare case reports of testicular lesions morphologically resembling gynandroblastomas are in fact variants of juvenile granulose cell tumor, or Sertoli cell tumor, or a combination of both."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 20709,
      "label": "ovarian sex cord-stromal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639,
        20309
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080369",
          "GARD:0012285",
          "MEDGEN:154644",
          "NCIT:C4862",
          "ONCOTREE:SCST",
          "UMLS:C0600113"
        ],
        "synonyms": [
          "Sex cord-stromal neoplasm of ovary",
          "Sex cord-stromal neoplasm of the ovary",
          "Sex cord-stromal tumor of ovary",
          "Sex cord-stromal tumor of the ovary",
          "Sex cord-stromal tumour of ovary",
          "Sex cord-stromal tumour of the ovary",
          "ovarian Sex cord-stromal neoplasm",
          "ovarian Sex cord-stromal tumor",
          "ovarian Sex cord-stromal tumour",
          "ovary sex cord-stromal tumor",
          "ovary sex cord-stromal tumour",
          "sex cord-stromal tumor of ovary",
          "sex cord-stromal tumour of ovary",
          "ovarian sex cord tumor with annular tubules",
          "ovarian sex cord tumour with annular tubules",
          "sex cord stromal tumor",
          "sex cord stromal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that arises from the ovary and is composed of granulosa cells, Sertoli cells, Leydig cells, theca cells, and fibroblasts. Representative examples include thecoma, fibroma, Sertoli cell tumor, and granulosa cell tumor."
      },
      "child_count": 12,
      "reference_id": "MONDO:0021657"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 20709,
      "label": "ovarian sex cord-stromal tumor"
    }
  ]
}