{
  "id": 19987,
  "label": "theca steroid-producing cell malignant tumor of ovary, not further specified",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020543",
  "properties": {
    "xrefs": [
      "GARD:0019708",
      "MEDGEN:904268",
      "Orphanet:99917",
      "UMLS:C4274494"
    ],
    "synonyms": [
      "theca (steroid-producing) cell cancer, not further specified"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Malignant steroid cell tumor of the ovary, not otherwise specified is a rare malignant sex cord stromal tumor of ovary of unknown histological lineage, occurring in adult women, characterized, in most cases, by manifestations of androgen excess (hirsutism, hair loss, amenorrhea, or oligomenorrhea) and, occasionally, Cushing syndrome."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18316,
      "label": "malignant sex cord stromal tumor of ovary",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18448,
        20709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018816",
          "MEDGEN:233667",
          "NCIT:C8053",
          "Orphanet:35808",
          "UMLS:C1334609"
        ],
        "synonyms": [
          "malignant Sex cord-stromal tumor of ovary",
          "malignant Sex cord-stromal tumor of the ovary",
          "malignant Sex cord-stromal tumour of ovary",
          "malignant Sex cord-stromal tumour of the ovary",
          "malignant ovarian SCST",
          "malignant ovarian Sex cord-stromal neoplasm",
          "malignant ovarian Sex cord-stromal tumor",
          "malignant ovarian Sex cord-stromal tumour",
          "malignant ovarian sex cord-stromal tumor",
          "malignant ovarian sex cord-stromal tumour",
          "ovarian sex cord-stromal tumor, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Malignant sex cord stromal tumor (SCST) of ovary is a rare ovarian cancer arising from granulosa, theca, sertoli and leydig cells or stromal fibroblasts, occurring at any age and presenting with abdominal or pelvic mass, and characterized (with the exception of fibroma) by the production of sex steroids resulting in manifestations of hormone excess, with a relatively favorable prognosis."
      },
      "child_count": 8,
      "reference_id": "MONDO:0018172"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18316,
      "label": "malignant sex cord stromal tumor of ovary"
    }
  ]
}