{
  "id": 19990,
  "label": "acute graft versus host disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020546",
  "properties": {
    "xrefs": [
      "GARD:0006544",
      "ICD10CM:D89.810",
      "ICD9:279.51",
      "MEDGEN:208987",
      "MedDRA:10066260",
      "NCIT:C4980",
      "Orphanet:99920",
      "SCTID:402355000",
      "UMLS:C0856825",
      "icd11.foundation:83784921"
    ],
    "synonyms": [
      "GVHD, acute",
      "acute graft vs. host disease",
      "fulminant graft versus host disease",
      "graft versus host disease, acute",
      "acute GVHD"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "A syndrome of immunologically mediated tissue damage that may occur following an allogeneic transplant, usually affecting the skin, liver, and GI tract. The onset is usually within one hundred days of transplantation or immunologic manipulation."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 14751,
      "label": "graft versus host disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6778,
        24617
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081267",
          "GARD:0016642",
          "ICD10CM:D89.81",
          "ICD9:279.50",
          "MEDGEN:9082",
          "MESH:D006086",
          "MedDRA:10018651",
          "NCIT:C3063",
          "NORD:1203",
          "Orphanet:39812",
          "SCTID:234646005",
          "UMLS:C0018133",
          "icd11.foundation:437372167"
        ],
        "synonyms": [
          "GVH",
          "GVHD",
          "GvHD",
          "disease, graft-versus-host",
          "disease, graft-vs-host",
          "diseases, graft-versus-host",
          "diseases, graft-vs-host",
          "graft versus host disease",
          "graft vs host disease",
          "graft vs. host disease",
          "graft-versus-host disease",
          "graft-versus-host-disease",
          "graft-vs-host disease",
          "runt disease",
          "disease, homologous wasting",
          "disease, runt",
          "graft-VS-host diseases",
          "graft-versus-host disease, resistance to",
          "graft-versus-host disease, susceptibility to",
          "graft-versus-host diseases",
          "homologous wasting disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "An immune system disorder that occurs after allogeneic hematopoietic stem cell transplant and is a reaction of donor immune cells against host tissues. Activated donor T cells damage host epithelial cells after an inflammatory cascade that begins with the preparative regimen."
      },
      "child_count": 4,
      "reference_id": "MONDO:0013730"
    },
    {
      "id": 20092,
      "label": "acute disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24492
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:1738",
          "MESH:D000208",
          "SCTID:2704003",
          "UMLS:C0001314"
        ],
        "synonyms": [
          "acute disease",
          "acute diseases",
          "disease, acute"
        ],
        "definition": "Disease having a short and relatively severe course."
      },
      "child_count": 119,
      "reference_id": "MONDO:0020683"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 14751,
      "label": "graft versus host disease"
    },
    {
      "id": 20092,
      "label": "acute disease"
    }
  ]
}