{
  "id": 19994,
  "label": "placental site trophoblastic tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020552",
  "properties": {
    "xrefs": [
      "DOID:3596",
      "EFO:1001111",
      "GARD:0007403",
      "ICDO:9104/1",
      "MEDGEN:104914",
      "MESH:D018245",
      "NCIT:C3757",
      "ONCOTREE:PSTT",
      "Orphanet:99928",
      "SCTID:237252008",
      "UMLS:C0206666"
    ],
    "synonyms": [
      "PSST",
      "placental site gestational trophoblastic tumor",
      "placental site gestational trophoblastic tumour",
      "placental site trophoblastic tumor",
      "placental site trophoblastic tumor (morphologic abnormality)",
      "placental site trophoblastic tumour (morphologic abnormality)",
      "placental-site GTT",
      "placental-site gestational trophoblastic neoplasm",
      "placental-site gestational trophoblastic tumor",
      "placental-site gestational trophoblastic tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "Placental site trophoblastic tumor is a rare gestational trophoblastic tumor (GTT) which develops from the placental implantation site and always occurs following pregnancy, voluntary termination of pregnancy (VTP) or miscarriage."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6924,
      "label": "choriocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4886,
        6773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3594",
          "EFO:0002893",
          "GARD:0006059",
          "HP:0100768",
          "ICDO:9100/3",
          "MEDGEN:40278",
          "MESH:D002822",
          "NANDO:2200070",
          "NCIT:C2948",
          "ONCOTREE:BCCA",
          "SCTID:188188009",
          "UMLS:C0008497"
        ],
        "synonyms": [
          "chorioblastoma",
          "choriocarcinoma",
          "choriocarcinoma (disease)",
          "choriocarcinoma, malignant",
          "chorioepithelioma",
          "chorion carcinoma",
          "chorionic carcinoma"
        ],
        "definition": "An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected."
      },
      "child_count": 16,
      "reference_id": "MONDO:0005207"
    },
    {
      "id": 18866,
      "label": "gestational trophoblastic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4886,
        20384,
        21520
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3590",
          "GARD:0006498",
          "ICD9:630",
          "MEDGEN:210107",
          "MedDRA:10061988",
          "NCIT:C4699",
          "Orphanet:59305",
          "SCTID:609519004",
          "UMLS:C1135868",
          "icd11.foundation:1972855304"
        ],
        "synonyms": [
          "gestational trophoblastic disease",
          "GTN",
          "GTT",
          "gestational trophoblastic tumor",
          "gestational trophoblastic tumour",
          "hydatidiform mole",
          "molar pregnancy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A diverse group of pregnancy-related tumors characterized by excessive proliferation of trophoblasts. Representative examples include hydatidiform mole, gestational choriocarcinoma, and placental site trophoblastic tumor."
      },
      "child_count": 18,
      "reference_id": "MONDO:0018944"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6924,
      "label": "choriocarcinoma"
    },
    {
      "id": 18866,
      "label": "gestational trophoblastic neoplasm"
    }
  ]
}