{
  "id": 20004,
  "label": "pleomorphic liposarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020562",
  "properties": {
    "xrefs": [
      "DOID:5702",
      "EFO:0003083",
      "GARD:0019719",
      "ICD9:171.9",
      "ICDO:8854/3",
      "MEDGEN:61457",
      "NCIT:C3705",
      "ONCOTREE:PLLS",
      "Orphanet:99969",
      "SCTID:404071006",
      "UMLS:C0205825"
    ],
    "synonyms": [
      "PLS",
      "pleomorphic liposarcoma",
      "pleomorphic liposarcoma (morphologic abnormality)",
      "PLLS"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "Pleomorphic liposarcoma (PLS), the rarest subtype of liposarcoma (LS), is an aggressive, fast growing tumor located usually in the deep soft tissues of the lower and upper extremities. It is characterized by a variable number of pleomorphic lipoblasts and, in contrast to dedifferentiated liposarcoma, it lacks any association with well-differentiated liposarcoma."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6790,
      "label": "liposarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4839,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3382",
          "EFO:0000569",
          "GARD:0006913",
          "ICD9:171.9",
          "ICDO:8850/3",
          "MEDGEN:44177",
          "MESH:D008080",
          "MedDRA:10024627",
          "NANDO:2200065",
          "NCIT:C3194",
          "NORD:1925",
          "ONCOTREE:LIPO",
          "Orphanet:69078",
          "SCTID:254829001",
          "UMLS:C0023827"
        ],
        "synonyms": [
          "lip sarcoma",
          "liposarcoma",
          "liposarcoma, malignant",
          "sarcoma of lip"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A usually painless malignant tumor that arises from adipose tissue. Microscopically, it may contain a spectrum of neoplastic adipocytes ranging from lipoblasts to pleomorphic malignant adipocytes. Morphologic variants include: well differentiated, dedifferentiated, pleomorphic, and myxoid liposarcoma. The metastatic potential is higher in less differentiated tumors."
      },
      "child_count": 38,
      "reference_id": "MONDO:0005060"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6790,
      "label": "liposarcoma"
    }
  ]
}