{
  "id": 20010,
  "label": "complex regional pain syndrome type 2",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020572",
  "properties": {
    "xrefs": [
      "DOID:3222",
      "EFO:1000854",
      "GARD:0019727",
      "MEDGEN:2918",
      "MESH:D002422",
      "MedDRA:10007825",
      "MedDRA:10064335",
      "NCIT:C121572",
      "Orphanet:99994",
      "SCTID:408751001",
      "UMLS:C0007462"
    ],
    "synonyms": [
      "CRPS II",
      "Complex regional pain syndrome II",
      "causalgia"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia, not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 19203,
      "label": "complex regional pain syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21350
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14022",
          "DOID:3223",
          "EFO:1001998",
          "GARD:0004647",
          "ICD10CM:M89.0",
          "MEDGEN:96846",
          "MESH:D020918",
          "MedDRA:10064332",
          "NORD:1652",
          "Orphanet:83452",
          "SCTID:128200000",
          "UMLS:C0458219",
          "icd11.foundation:1834504950"
        ],
        "synonyms": [
          "CRPS",
          "algoneurodystrophy",
          "reflex sympathetic dystrophy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A chronic pain syndrome characterized by a disproportionate spontaneous or stimulus-induced pain, accompanied by a variably mixed myriad of autonomic and motor disorders including symptoms such as swelling, allodynia, skin blood supply and trophic disturbances. CRPS most often affects one of the arms, legs, hands, or feet and usually occurs after an injury or trauma to that limb."
      },
      "child_count": 2,
      "reference_id": "MONDO:0019369"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 19203,
      "label": "complex regional pain syndrome"
    }
  ]
}