{
  "id": 20025,
  "label": "lung PEComa",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020588",
  "properties": {
    "xrefs": [
      "GARD:0025181",
      "MEDGEN:1639012",
      "NCIT:C142783",
      "UMLS:C4684821"
    ],
    "synonyms": [
      "lung PEComa",
      "lung pecomatous tumor",
      "lung pecomatous tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A lung tumor that arises from perivascular epithelioid cells (PECs)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7885,
      "label": "neoplasm with perivascular epithelioid cell differentiation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7941
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2643",
          "EFO:1000464",
          "GARD:0022383",
          "MEDGEN:266246",
          "MESH:D054973",
          "NCIT:C38150",
          "ONCOTREE:PECOMA",
          "Orphanet:595133",
          "UMLS:C1300127"
        ],
        "synonyms": [
          "PEComa",
          "neoplasm with perivascular epithelioid cell differentiation",
          "perivascular epithelioid cell neoplasm",
          "perivascular epithelioid cell tumour",
          "tumor with perivascular epithelioid cell differentiation",
          "tumour with perivascular epithelioid cell differentiation"
        ],
        "definition": "A soft tissue neoplasm composed of perivascular epithelioid cells. Representative examples include angiomyolipoma, clear cell-sugar-tumor of the lung, and lymphangioleiomyomatosis."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006359"
    },
    {
      "id": 20356,
      "label": "lung neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971,
        20056,
        20518
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:7400",
          "MESH:D008175",
          "NCIT:C3200",
          "ONCOTREE:LUNG",
          "UMLS:C0024121"
        ],
        "synonyms": [
          "lung neoplasm",
          "lung neoplasm (disease)",
          "lung neoplasms",
          "lung tumor",
          "lung tumour",
          "neoplasm of lung",
          "neoplasm of the lung",
          "tumor of lung",
          "tumor of the lung",
          "tumour of lung",
          "tumour of the lung",
          "lung",
          "neoplasm, lung",
          "neoplasm, pulmonary",
          "neoplasms, lung",
          "neoplasms, pulmonary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm involving the lungs. Representative examples of benign neoplasms include adenoma, papilloma, chondroma, and endobronchial lipoma. Representative examples of malignant neoplasms include carcinoma, carcinoid tumor, sarcoma, and lymphoma."
      },
      "child_count": 30,
      "reference_id": "MONDO:0021117"
    }
  ],
  "children": [
    {
      "id": 5526,
      "label": "clear cell-sugar-tumor of the lung",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4769,
        20018,
        20025
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5763",
          "GARD:0023595",
          "MEDGEN:232370",
          "NCIT:C38152",
          "UMLS:C1333065"
        ],
        "synonyms": [
          "CCSTL",
          "Sugar tumor",
          "Sugar tumour",
          "clear cell-Sugar-tumor of lung",
          "clear cell-Sugar-tumor of the lung",
          "lung clear cell tumor",
          "lung clear cell tumour",
          "lung clear cell-sugar-tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare benign lung tumor with perivascular epithelioid cell differentiation. It is composed of round or oval cells with abundant clear or eosinophilic cytoplasm and distinct cell borders. The vast majority of patients are asymptomatic and the tumors are discovered incidentally. Excision is curative."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003637"
    },
    {
      "id": 7820,
      "label": "lung lymphangioleiomyomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12793,
        20025
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3319",
          "EFO:1000334",
          "GARD:0003319",
          "ICD9:518.89",
          "MEDGEN:91161",
          "MedDRA:10049459",
          "NCIT:C38153",
          "ONCOTREE:LAM",
          "Orphanet:538",
          "SCTID:277844007",
          "UMLS:C0349649"
        ],
        "synonyms": [
          "Lymphangioleiomyomatosis",
          "lymphangioleiomyomatosis",
          "lung lymphangioleiomyomatosis",
          "lung lymphangiomyomatosis",
          "pulmonary lymphangiomyomatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Lymphangiomyomatosis involving the lungs and local lymph nodes. Patients usually present with chylous pleural effusion. The clinical course is variable. Patients with resectable lesions usually have a favorable clinical outcome. Patients with diffuse lesions usually have a progressive clinical course."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006277"
    }
  ],
  "roots": [
    {
      "id": 7885,
      "label": "neoplasm with perivascular epithelioid cell differentiation"
    },
    {
      "id": 20356,
      "label": "lung neoplasm"
    }
  ]
}