{
  "id": 20050,
  "label": "anaplastic meningioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020635",
  "properties": {
    "xrefs": [
      "GARD:0025191",
      "ICDO:9530/3",
      "MEDGEN:75478",
      "NCIT:C4051",
      "ONCOTREE:ANM",
      "UMLS:C0259785"
    ],
    "synonyms": [
      "anaplastic (malignant) meningioma",
      "anaplastic meningioma",
      "malignant meningioma",
      "meningioma, anaplastic, malignant",
      "meningioma, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A WHO grade III meningioma characterized by the presence of malignant morphologic features, including malignant cytology and a very high mitotic index (20 or more mitoses per ten high power fields)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 20048,
      "label": "anaplastic cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:231373",
          "NCIT:C36025",
          "UMLS:C1332287"
        ],
        "synonyms": [
          "anaplastic malignant neoplasm"
        ]
      },
      "child_count": 8,
      "reference_id": "MONDO:0020633"
    },
    {
      "id": 20049,
      "label": "grade III meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17113
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025190",
          "MEDGEN:79186",
          "NCIT:C38938",
          "UMLS:C0280801"
        ],
        "synonyms": [
          "WHO grade III meningioma",
          "grade 3 meningioma",
          "grade III meningioma",
          "meningioma, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant meningioma with aggressive clinical course. It recurs in approximately 50-78% of the cases. This category includes the anaplastic (malignant) meningioma, papillary meningioma, and rhabdoid meningioma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0020634"
    },
    {
      "id": 20078,
      "label": "high grade malignant neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:234350",
          "NCIT:C36046",
          "UMLS:C1334017"
        ],
        "synonyms": [
          "high grade malignant neoplasm"
        ]
      },
      "child_count": 3,
      "reference_id": "MONDO:0020665"
    },
    {
      "id": 20501,
      "label": "malignant tumor of meninges",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        17192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025313",
          "ICD10CM:C70",
          "MEDGEN:87594",
          "NCIT:C4628",
          "SCTID:363497007",
          "UMLS:C0348375"
        ],
        "synonyms": [
          "cancer of meningeal cluster",
          "cancer of meninges",
          "cancer of the meninges",
          "malignant meningeal cluster neoplasm",
          "malignant meningeal neoplasms",
          "malignant meningeal tumor",
          "malignant meningeal tumour",
          "malignant meninges neoplasm",
          "malignant meninges tumor",
          "malignant meninges tumour",
          "malignant neoplasm of meningeal cluster",
          "malignant neoplasm of meninges",
          "malignant neoplasm of the meninges",
          "malignant neoplasms of meninges",
          "malignant tumor of the meninges",
          "malignant tumour of the meninges",
          "meningeal cancer",
          "meningeal cluster cancer",
          "meningeal tumors, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A cancer that involves the meningeal cluster."
      },
      "child_count": 20,
      "reference_id": "MONDO:0021322"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 20048,
      "label": "anaplastic cancer"
    },
    {
      "id": 20049,
      "label": "grade III meningioma"
    },
    {
      "id": 20078,
      "label": "high grade malignant neoplasm"
    },
    {
      "id": 20501,
      "label": "malignant tumor of meninges"
    }
  ]
}