{
  "id": 20056,
  "label": "respiratory tract neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020641",
  "properties": {
    "xrefs": [
      "EFO:0003853",
      "ICD10CM:C30-C39",
      "MEDGEN:11200",
      "MESH:D012142",
      "NCIT:C3355",
      "SCTID:126667002",
      "UMLS:C0035244"
    ],
    "synonyms": [
      "neoplasm of respiratory tract",
      "neoplasm of the respiratory tract",
      "neoplasm, respiratory tract",
      "neoplasms, respiratory tract",
      "respiratory system neoplasm",
      "respiratory tract neoplasm",
      "respiratory tract tumor",
      "respiratory tract tumour",
      "tract neoplasm, respiratory",
      "tract neoplasms, respiratory",
      "tumor of respiratory tract",
      "tumor of the respiratory tract",
      "tumour of respiratory tract",
      "tumour of the respiratory tract"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A benign or malignant, primary or metastatic neoplasm involving the respiratory tract."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 6798,
      "label": "neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21214
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14566",
          "EFO:0000616",
          "HP:0002664",
          "ICD10CM:C00-D49",
          "ICD10CM:C7A-C7A",
          "ICD10CM:C7B-C7B",
          "ICD9:140-239",
          "ICD9:239.8",
          "ICD9:239.9",
          "MEDGEN:10294",
          "MESH:D009369",
          "NCIT:C3262",
          "ONCOTREE:OTHER",
          "SCTID:55342001",
          "UMLS:C0027651"
        ],
        "synonyms": [
          "cell process disease",
          "disease of cellular proliferation",
          "neoplasia",
          "neoplasm",
          "neoplasm (disease)",
          "neoplastic disease",
          "neoplastic growth",
          "tumor",
          "tumor disease",
          "tumour",
          "tumour disease",
          "other neoplasm"
        ],
        "definition": "A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005070"
    },
    {
      "id": 6815,
      "label": "respiratory system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1579",
          "EFO:0000684",
          "ICD10CM:J00-J99",
          "ICD9:460-519",
          "ICD9:500-508",
          "ICD9:503",
          "ICD9:508",
          "ICD9:508.1",
          "ICD9:508.8",
          "ICD9:508.9",
          "ICD9:510-519",
          "ICD9:516",
          "ICD9:516.8",
          "ICD9:516.9",
          "ICD9:517",
          "ICD9:517.8",
          "ICD9:519",
          "ICD9:519.1",
          "ICD9:519.3",
          "ICD9:519.8",
          "ICD9:519.9",
          "ICD9:V12.60",
          "ICD9:V47.2",
          "MEDGEN:48421",
          "MESH:D012140",
          "NANDO:1100010",
          "NCIT:C26871",
          "SCTID:50043002",
          "UMLS:C0035204"
        ],
        "synonyms": [
          "disease of respiratory system",
          "disease or disorder of respiratory system",
          "disorder of respiratory system",
          "respiratory disease",
          "respiratory disorder",
          "respiratory system disease",
          "respiratory system disease or disorder",
          "respiratory system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma."
      },
      "child_count": 59,
      "reference_id": "MONDO:0005087"
    }
  ],
  "children": [
    {
      "id": 4833,
      "label": "bronchial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3582,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3906",
          "EFO:1000849",
          "HP:0030077",
          "MEDGEN:2735",
          "MESH:D001984",
          "NANDO:2200081",
          "SCTID:126705004",
          "UMLS:C0006264"
        ],
        "synonyms": [
          "bronchial neoplasm",
          "bronchial neoplasm (disease)",
          "bronchus neoplasm (disease)",
          "bronchus tumor",
          "bronchus tumour",
          "neoplasm of bronchus",
          "tumor of bronchus",
          "tumour of bronchus"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Tumors or cancer of the bronchi."
      },
      "child_count": 10,
      "reference_id": "MONDO:0002807"
    },
    {
      "id": 6527,
      "label": "nasal cavity neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4349,
        7231,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9310",
          "MEDGEN:138023",
          "NCIT:C4413",
          "SCTID:126670003",
          "UMLS:C0345630"
        ],
        "synonyms": [
          "nasal cavity neoplasm",
          "nasal cavity neoplasm (disease)",
          "nasal cavity tumor",
          "nasal cavity tumour",
          "neoplasm of nasal cavity",
          "neoplasm of the nasal cavity",
          "tumor of nasal cavity",
          "tumor of the nasal cavity",
          "tumour of nasal cavity",
          "tumour of the nasal cavity"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the nasal cavity. Representative examples of benign neoplasms include Schneiderian papilloma and salivary gland-type adenoma. Representative examples of malignant neoplasms include carcinoma and lymphoma."
      },
      "child_count": 9,
      "reference_id": "MONDO:0004756"
    },
    {
      "id": 7056,
      "label": "nasopharyngeal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6581,
        7231,
        20056,
        20455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004252",
          "MEDGEN:6526",
          "MESH:D009303",
          "NCIT:C3257",
          "SCTID:126680004",
          "UMLS:C0027439"
        ],
        "synonyms": [
          "nasopharyngeal neoplasms",
          "nasopharyngeal tumor",
          "nasopharyngeal tumour",
          "nasopharynx neoplasm",
          "nasopharynx neoplasm (disease)",
          "nasopharynx tumor",
          "nasopharynx tumour",
          "neoplasm of nasopharynx",
          "neoplasm of the nasopharynx",
          "tumor of nasopharynx",
          "tumor of the nasopharynx",
          "tumour of nasopharynx",
          "tumour of the nasopharynx"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the nasopharynx. Representative examples of benign neoplasms include angiofibroma and squamous papilloma. Representative examples of malignant neoplasms include keratinizing squamous cell carcinoma and nonkeratinizing carcinoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005375"
    },
    {
      "id": 18726,
      "label": "SMARCA4-deficient sarcoma of thorax",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2875,
        18239,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080532",
          "GARD:0021943",
          "MEDGEN:1806595",
          "NCIT:C183115",
          "Orphanet:466962",
          "UMLS:C5554190"
        ],
        "synonyms": [
          "SMARCA4-deficient thoracic sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018761"
    },
    {
      "id": 20306,
      "label": "pleural neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4184,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:18523",
          "MESH:D010997",
          "NCIT:C3332",
          "ONCOTREE:PLEURA",
          "SCTID:126719004",
          "UMLS:C0032229"
        ],
        "synonyms": [
          "neoplasm of pleura",
          "neoplasm of pleural cavity",
          "neoplasm of the pleura",
          "pleura neoplasm",
          "pleura neoplasm (disease)",
          "pleura tumor",
          "pleura tumour",
          "pleural cavity neoplasm (disease)",
          "pleural cavity tumor",
          "pleural cavity tumour",
          "pleural neoplasm",
          "pleural tumor",
          "pleural tumour",
          "tumor of pleura",
          "tumor of the pleura",
          "tumour of pleura",
          "tumour of the pleura"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that involves the serous membrane that lines the lungs and thoracic cavity. Most pleural neoplasms are metastatic. Diffuse malignant mesothelioma is the most common primary malignant neoplasm of the pleura."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021065"
    },
    {
      "id": 20312,
      "label": "laryngeal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6195,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003817",
          "MEDGEN:7271",
          "MESH:D007822",
          "NCIT:C3156",
          "SCTID:126692004",
          "UMLS:C0023055"
        ],
        "synonyms": [
          "laryngeal neoplasm",
          "laryngeal tumor",
          "laryngeal tumour",
          "larynx neoplasm",
          "larynx neoplasm (disease)",
          "larynx tumor",
          "larynx tumour",
          "neoplasm of larynx",
          "neoplasm of the larynx",
          "tumor of larynx",
          "tumor of the larynx",
          "tumour of larynx",
          "tumour of the larynx"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm involving the larynx."
      },
      "child_count": 12,
      "reference_id": "MONDO:0021071"
    },
    {
      "id": 20356,
      "label": "lung neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971,
        20056,
        20518
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:7400",
          "MESH:D008175",
          "NCIT:C3200",
          "ONCOTREE:LUNG",
          "UMLS:C0024121"
        ],
        "synonyms": [
          "lung neoplasm",
          "lung neoplasm (disease)",
          "lung neoplasms",
          "lung tumor",
          "lung tumour",
          "neoplasm of lung",
          "neoplasm of the lung",
          "tumor of lung",
          "tumor of the lung",
          "tumour of lung",
          "tumour of the lung",
          "lung",
          "neoplasm, lung",
          "neoplasm, pulmonary",
          "neoplasms, lung",
          "neoplasms, pulmonary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm involving the lungs. Representative examples of benign neoplasms include adenoma, papilloma, chondroma, and endobronchial lipoma. Representative examples of malignant neoplasms include carcinoma, carcinoid tumor, sarcoma, and lymphoma."
      },
      "child_count": 30,
      "reference_id": "MONDO:0021117"
    },
    {
      "id": 20428,
      "label": "trachea neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4630,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001437",
          "GTR:AN0481062",
          "GTR:AN0505660",
          "HP:0100551",
          "MEDGEN:21602",
          "MESH:D014134",
          "NCIT:C3419",
          "UMLS:C0040582"
        ],
        "synonyms": [
          "neoplasm of the trachea",
          "neoplasm of trachea",
          "trachea neoplasm (disease)",
          "trachea tumor",
          "trachea tumour",
          "tracheal neoplasm",
          "tracheal tumor",
          "tracheal tumour",
          "tumor of the trachea",
          "tumor of trachea",
          "tumour of the trachea",
          "tumour of trachea"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the trachea."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021210"
    }
  ],
  "roots": [
    {
      "id": 6798,
      "label": "neoplasm"
    },
    {
      "id": 6815,
      "label": "respiratory system disorder"
    }
  ]
}