{
  "id": 20076,
  "label": "malignant spindle cell neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020663",
  "properties": {
    "xrefs": [
      "MEDGEN:90746",
      "NCIT:C27091",
      "UMLS:C0334230"
    ],
    "synonyms": [
      "malignant spindle cell neoplasm",
      "malignant spindle cell tumor",
      "malignant spindle cell tumour",
      "spindle cell cancer"
    ],
    "definition": "A malignant neoplasm characterized by the presence of atypical spindle cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6733,
      "label": "cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050686",
          "DOID:0050687",
          "DOID:162",
          "ICD9:195.8",
          "ICD9:199",
          "ICD9:199.1",
          "ICDO:8000/3",
          "MEDGEN:14297",
          "NCIT:C9305",
          "ONCOTREE:MT",
          "SCTID:363346000",
          "UMLS:C0006826",
          "birnlex:406"
        ],
        "synonyms": [
          "CA",
          "cancer",
          "cell type cancer",
          "malignancy",
          "malignant growth",
          "malignant neoplasm",
          "malignant neoplasm (disease)",
          "malignant neoplastic disease",
          "malignant tumor",
          "malignant tumour",
          "neoplasm (disease), malignant",
          "neoplasm, malignant",
          "MT"
        ],
        "definition": "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas."
      },
      "child_count": 33,
      "reference_id": "MONDO:0004992"
    },
    {
      "id": 20077,
      "label": "spindle cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000705",
          "MEDGEN:234806",
          "NCIT:C27263",
          "UMLS:C1336052"
        ],
        "synonyms": [
          "spindle cell neoplasm",
          "spindle cell tumor",
          "spindle cell tumour"
        ],
        "definition": "A benign or malignant neoplasm characterized by the presence of neoplastic spindle cells."
      },
      "child_count": 5,
      "reference_id": "MONDO:0020664"
    }
  ],
  "children": [
    {
      "id": 4933,
      "label": "spindle cell sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        20076
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4235",
          "ICDO:8801/3",
          "MEDGEN:64477",
          "NCIT:C27005",
          "UMLS:C0205945"
        ],
        "synonyms": [
          "spindle cell sarcoma"
        ],
        "definition": "A malignant mesenchymal neoplasm composed of spindle-shaped cells. This is a morphologic term which can be applied to a wide range of sarcomas."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002927"
    },
    {
      "id": 5624,
      "label": "spindle cell intraocular melanoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7943,
        7983,
        20076
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6037",
          "GARD:0023646",
          "MEDGEN:76015",
          "NCIT:C7986",
          "UMLS:C0279687"
        ],
        "synonyms": [
          "spindle cell melanoma of the uvea",
          "spindle cell melanoma of uvea",
          "spindle cell uveal melanoma",
          "uveal spindle cell melanoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A melanoma arising from the choroid, ciliary body, or the iris. It is characterized by the presence of spindle-shaped melanocytes."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003744"
    },
    {
      "id": 7925,
      "label": "sarcomatoid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        20048,
        20076
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4015",
          "EFO:1000520",
          "ICDO:8032/3",
          "ICDO:8033/3",
          "MEDGEN:60009",
          "NCIT:C27004",
          "UMLS:C0205697"
        ],
        "synonyms": [
          "carcinoma, spindle cell, malignant",
          "pseudosarcomatous carcinoma",
          "sarcomatoid carcinoma",
          "spindle cell carcinoma",
          "spindle cell carcinoma (morphologic abnormality)"
        ],
        "definition": "A malignant epithelial neoplasm characterized by the presence of spindle cells and anaplastic morphologic features. Giant cells and a sarcomatous component may also be present."
      },
      "child_count": 24,
      "reference_id": "MONDO:0006406"
    },
    {
      "id": 23439,
      "label": "desmoplastic melanoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6750,
        7943,
        20076
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:232127",
          "NCIT:C37257",
          "ONCOTREE:DESM",
          "UMLS:C1333280"
        ],
        "synonyms": [
          "desmoplastic cutaneous (skin) melanoma",
          "desmoplastic melanoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A melanoma of the skin characterized by a proliferation of atypical spindled melanocytes in the dermis, in a background of abundant collagen. It usually presents as an amelanotic raised nodular lesion."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044785"
    }
  ],
  "roots": [
    {
      "id": 6733,
      "label": "cancer"
    },
    {
      "id": 20077,
      "label": "spindle cell neoplasm"
    }
  ]
}