{
  "id": 20084,
  "label": "vascular insufficiency disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020674",
  "properties": {
    "xrefs": [
      "MEDGEN:534461",
      "SCTID:86341008",
      "UMLS:C0232352"
    ],
    "synonyms": [
      "vascular insufficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 7065,
      "label": "vascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:178",
          "EFO:0004264",
          "ICD10CM:I00-I99",
          "ICD10CM:I70-I79",
          "ICD9:442.9",
          "MEDGEN:22621",
          "MESH:D014652",
          "NANDO:2100294",
          "NCIT:C35117",
          "SCTID:27550009",
          "UMLS:C0042373"
        ],
        "synonyms": [
          "disease of vasculature",
          "disease or disorder of vasculature",
          "disorder of vasculature",
          "vascular disorder",
          "vasculature disease",
          "vasculature disease or disorder",
          "vasculopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005385"
    }
  ],
  "children": [
    {
      "id": 3214,
      "label": "venous insufficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6420,
        20084
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10128",
          "HP:0005293",
          "ICD9:459.81",
          "MEDGEN:21841",
          "MESH:D014689",
          "SCTID:20696009",
          "UMLS:C0042485"
        ],
        "synonyms": [
          "venous insufficiency",
          "venous insufficiency (disease)",
          "peripheral venous insufficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with edema and sometimes with venous stasis ulcers at the ankle."
      },
      "child_count": 4,
      "reference_id": "MONDO:0000945"
    },
    {
      "id": 3531,
      "label": "congenital mitral valve insufficiency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20084,
        29227
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:Q23.3",
          "ICD9:396.3",
          "ICD9:746.6",
          "MEDGEN:510600",
          "NANDO:2200303",
          "NCIT:C197881",
          "SCTID:29928006",
          "UMLS:C0158619",
          "icd11.foundation:403917903"
        ],
        "synonyms": [
          "congenital insufficiency of mitral valve",
          "congenital mitral insufficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Mitral valve insufficiency that is present at birth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001298"
    },
    {
      "id": 3810,
      "label": "vertebrobasilar insufficiency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20084
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13003",
          "EFO:1001449",
          "ICD9:435.3",
          "MEDGEN:12075",
          "MESH:D014715",
          "SCTID:195199008",
          "UMLS:C0042568",
          "icd11.foundation:1570524591"
        ],
        "synonyms": [
          "vertebrobasilar arterial insufficiency",
          "vertebrobasilar artery syndrome",
          "vertebrobasilar insufficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Localized or diffuse reduction in blood flow through the vertebrobasilar arterial system, which supplies the brain stem; cerebellum; occipital lobe; medial temporal lobe; and thalamus. Characteristic clinical features include syncope; lightheadedness; visual disturbances; and vertigo. brain stem infarctions or other brain infarction may be associated."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001613"
    },
    {
      "id": 3827,
      "label": "vertebral artery insufficiency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2933,
        4370,
        6964,
        20084
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13095",
          "ICD9:435.1",
          "MEDGEN:22638",
          "NCIT:C35123",
          "SCTID:34781003",
          "UMLS:C0042560",
          "icd11.foundation:1541569386"
        ],
        "synonyms": [
          "vertebral artery syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A syndrome which occurs as a result of the occlusion of one of the vertebral arteries. It may be caused by atherosclerosis, embolism or hemorrhage. Collateral circulation through the circle of Willis is usually comprised as well. Clinical signs may include vertigo, nystagmus, dysarthria, ataxia and sensorimotor deficits. Clinical course may lead to persistence of neurologic deficits. Prognosis is variable with a substantial risk for recurrent infarction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001631"
    },
    {
      "id": 4366,
      "label": "basilar artery insufficiency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2933,
        4370,
        20084
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:223",
          "ICD9:435.0",
          "MEDGEN:14039",
          "NCIT:C34413",
          "SCTID:64009001",
          "UMLS:C0004812",
          "icd11.foundation:440367679"
        ],
        "synonyms": [
          "basilar artery syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A syndrome which occurs as a result of the occlusion of the basilar artery. It may be caused by atherosclerosis, embolism or hemorrhage. Clinical signs include dizziness, headache, vomiting, hemiparesis or hemiplegia, dysarthria, dysphagia, blurred vision and loss of consciousness. The clinical course is variable and is dependent upon the extent of the occlusion and the location of the clot along the basilar artery which determines the resultant neurologic impairment. Prognosis is dismal in cases where a complete occlusion occurs with rapid deterioration of neurological function."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002250"
    },
    {
      "id": 4884,
      "label": "tricuspid valve insufficiency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2932,
        20084
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4080",
          "MEDGEN:11911",
          "MESH:D014262",
          "NANDO:2200301",
          "NCIT:C50842",
          "SCTID:111287006",
          "UMLS:C0040961",
          "icd11.foundation:770887951"
        ],
        "synonyms": [
          "insufficiency, tricuspid",
          "tricuspid insufficiency",
          "tricuspid valve regurgitation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "The backflow of blood from the right ventricle into the right atrium, owning to imperfect functioning/insufficiency of the tricuspid valve."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002870"
    },
    {
      "id": 6411,
      "label": "chronic intestinal vascular insufficiency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6756,
        20084
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8633",
          "ICD9:557.1",
          "MEDGEN:90228",
          "SCTID:111354009",
          "UMLS:C0311262"
        ],
        "synonyms": [
          "chronic mesenteric ischemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0004622"
    },
    {
      "id": 7284,
      "label": "aortic valve insufficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5678,
        20084
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:57",
          "EFO:0007148",
          "ICD10CM:I06.1",
          "ICD9:395.1",
          "ICD9:396.3",
          "MEDGEN:8153",
          "MESH:D001022",
          "NANDO:2200307",
          "NCIT:C51223",
          "SCTID:78031003",
          "UMLS:C0003504",
          "icd11.foundation:1548485475"
        ],
        "synonyms": [
          "aortic insufficiency",
          "rheumatic aortic insufficiency",
          "rheumatic aortic regurgitation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Dysfunction of the aortic valve characterized by incomplete valve closure."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005648"
    },
    {
      "id": 8403,
      "label": "splenic infarction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4438,
        20084
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2533",
          "EFO:1001190",
          "GARD:0009973",
          "ICD10CM:D73.5",
          "ICD9:289.59",
          "MEDGEN:52468",
          "MESH:D013159",
          "MedDRA:10041648",
          "SCTID:22996003",
          "UMLS:C0037998"
        ],
        "synonyms": [
          "infarct of the spleen",
          "splenic infarcts"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Insufficiency of arterial or venous blood supply to the spleen due to emboli, thrombi, vascular torsion, or pressure that produces a macroscopic area of necrosis. (From Stedman, 25th ed)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0006978"
    }
  ],
  "roots": [
    {
      "id": 7065,
      "label": "vascular disorder"
    }
  ]
}