{
  "id": 20193,
  "label": "colorectal medullary carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020794",
  "properties": {
    "xrefs": [
      "MEDGEN:317525",
      "NCIT:C43590",
      "UMLS:C1707438"
    ],
    "synonyms": [
      "colorectal medullary carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A rare, invasive colorectal adenocarcinoma characterized by the presence of sheets of malignant epithelial cells with vesicular nuclei, prominent nucleoli, and abundant eosinophilic cytoplasm. It usually has a favorable prognosis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6746,
      "label": "colorectal adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        21360
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050861",
          "DOID:0050913",
          "EFO:0000365",
          "MEDGEN:230816",
          "NCIT:C5105",
          "ONCOTREE:COADREAD",
          "SCTID:408645001",
          "UMLS:C1319315"
        ],
        "synonyms": [
          "adenocarcinoma of large bowel",
          "adenocarcinoma of large intestine",
          "adenocarcinoma of the large bowel",
          "adenocarcinoma of the large intestine",
          "colorectal (colon or rectal) adenocarcinoma",
          "colorectal adenocarcinoma",
          "colorectum adenocarcinoma",
          "large bowel adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "The most common type of colorectal carcinoma. It is characterized by the presence of malignant glandular epithelial cells invading through the muscularis mucosa into the submucosa. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005008"
    }
  ],
  "children": [
    {
      "id": 3172,
      "label": "colon medullary carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4386,
        20193
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080183",
          "MEDGEN:363630",
          "NCIT:C60641",
          "ONCOTREE:CMC",
          "UMLS:C1880119"
        ],
        "synonyms": [
          "colon medullary carcinoma",
          "medullary carcinoma of the colon",
          "medullary colon carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A rare, invasive colon adenocarcinoma characterized by the presence of sheets of malignant epithelial cells with vesicular nuclei, prominent nucleoli, and abundant eosinophilic cytoplasm. It usually has a favorable prognosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000892"
    },
    {
      "id": 20200,
      "label": "rectal medullary carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4295,
        20193
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:364314",
          "NCIT:C60640",
          "UMLS:C1882915"
        ],
        "synonyms": [
          "rectal medullary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A rare, invasive rectal adenocarcinoma characterized by the presence of sheets of malignant epithelial cells with vesicular nuclei, prominent nucleoli, and abundant eosinophilic cytoplasm. It usually has a favorable prognosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020801"
    }
  ],
  "roots": [
    {
      "id": 6746,
      "label": "colorectal adenocarcinoma"
    }
  ]
}