{
  "id": 20200,
  "label": "rectal medullary carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020801",
  "properties": {
    "xrefs": [
      "MEDGEN:364314",
      "NCIT:C60640",
      "UMLS:C1882915"
    ],
    "synonyms": [
      "rectal medullary carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A rare, invasive rectal adenocarcinoma characterized by the presence of sheets of malignant epithelial cells with vesicular nuclei, prominent nucleoli, and abundant eosinophilic cytoplasm. It usually has a favorable prognosis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4295,
      "label": "rectum adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6746,
        23485
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1996",
          "EFO:0005631",
          "MEDGEN:56214",
          "NCIT:C9383",
          "ONCOTREE:READ",
          "SCTID:254582000",
          "UMLS:C0149978",
          "icd11.foundation:1316028436"
        ],
        "synonyms": [
          "adenocarcinoma - rectum",
          "adenocarcinoma of rectum",
          "adenocarcinoma of the rectum",
          "rectal adenocarcinoma",
          "rectum adenocarcinoma",
          "read"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An adenocarcinoma arising from the rectum. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, rectal adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002169"
    },
    {
      "id": 20193,
      "label": "colorectal medullary carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6746
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:317525",
          "NCIT:C43590",
          "UMLS:C1707438"
        ],
        "synonyms": [
          "colorectal medullary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A rare, invasive colorectal adenocarcinoma characterized by the presence of sheets of malignant epithelial cells with vesicular nuclei, prominent nucleoli, and abundant eosinophilic cytoplasm. It usually has a favorable prognosis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020794"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4295,
      "label": "rectum adenocarcinoma"
    },
    {
      "id": 20193,
      "label": "colorectal medullary carcinoma"
    }
  ]
}