{
  "id": 20201,
  "label": "basal cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020804",
  "properties": {
    "xrefs": [
      "EFO:0004193",
      "MEDGEN:2870",
      "MESH:D002280",
      "NCIT:C156767",
      "NCIT:C7586",
      "UMLS:C0007117"
    ],
    "synonyms": [
      "basal cell cancer",
      "epithelioma, basal cell",
      "malignant basal cell neoplasm"
    ],
    "definition": "A carcinoma involving the basal cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    },
    {
      "id": 20198,
      "label": "basal cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001763",
          "ICDO:8090/1",
          "MEDGEN:104921",
          "MESH:D018295",
          "NCIT:C3784",
          "SCTID:127570002",
          "UMLS:C0206710"
        ],
        "synonyms": [
          "basal cell tumor",
          "basal cell tumour",
          "neoplasm, basal cell"
        ],
        "definition": "A neoplastic proliferation of basal cells in the epidermis (part of the skin) or other anatomic sites (most frequently the salivary glands). The basal cell neoplastic proliferation in the epidermis results in basal cell carcinomas. The basal cell neoplastic proliferation in the salivary glands can be benign, resulting in basal cell adenomas or malignant, resulting in basal cell adenocarcinomas."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020799"
    }
  ],
  "children": [
    {
      "id": 7027,
      "label": "skin basal cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4707,
        20201
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-2719",
          "DOID:2513",
          "HP:0002671",
          "ICDO:8090/3",
          "MEDGEN:1648304",
          "NCIT:C2921",
          "ONCOTREE:BCC",
          "SCTID:254701007",
          "UMLS:C4721806"
        ],
        "synonyms": [
          "BCC",
          "basal cell cancer",
          "basal cell carcinoma",
          "basal cell tumor",
          "basal cell tumour",
          "basal cell tumour (morphologic abnormality)",
          "malignant basal cell tumour",
          "malignant basal cell tumour (morphologic abnormality)",
          "basal cell carcinoma of skin",
          "basal cell carcinoma of the skin",
          "basal cell epithelioma",
          "basal cell skin carcinoma",
          "skin basal cell cancer",
          "skin basal cell carcinoma",
          "epithelioma basal cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas."
      },
      "child_count": 50,
      "reference_id": "MONDO:0005341"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    },
    {
      "id": 20198,
      "label": "basal cell neoplasm"
    }
  ]
}