{
  "id": 20205,
  "label": "testicular sertoli cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020808",
  "properties": {
    "xrefs": [
      "GARD:0025254",
      "MEDGEN:91165",
      "NCIT:C4672",
      "UMLS:C0349671"
    ],
    "synonyms": [
      "Sertoli Cell Neoplasm of Testis",
      "Sertoli Cell Neoplasm of the Testis",
      "Sertoli Cell Tumor of Testis",
      "Sertoli Cell Tumor of the Testis",
      "Sertoli Cell Tumour of Testis",
      "Sertoli Cell Tumour of the Testis",
      "Testicular Sertoli Cell Neoplasm",
      "Testicular Sertoli Cell Tumor",
      "Testicular Sertoli Cell Tumor, NOS",
      "Testicular Sertoli Cell Tumor, Not Otherwise Specified",
      "Testicular Sertoli Cell Tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A sex cord-stromal tumor that arises from the testis and is characterized by the presence of neoplastic cells with features of Sertoli cells. It usually presents as a slow growing testicular mass. The vast majority of cases follow a benign clinical course."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4740,
      "label": "Sertoli cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3577",
          "ICDO:8630/1",
          "ICDO:8640/1",
          "MEDGEN:11387",
          "MESH:D012707",
          "NCIT:C39976",
          "UMLS:C0036769"
        ],
        "synonyms": [
          "Sertoli cell tumor",
          "tubular androblastoma NOS (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A sex cord-stromal tumor of the testis or the ovary. It is characterized by the presence of Sertoli cells forming tubules. Leydig cells are rare or absent. It may be associated with Peutz-Jeghers syndrome. In males, the presenting symptom is a slow growing testicular mass. Most cases follow a benign clinical course. In females it may present with estrogenic or androgenic manifestations. The vast majority of cases have a benign clinical course."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002696"
    },
    {
      "id": 5102,
      "label": "testicular sex cord-stromal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4757",
          "GARD:0021551",
          "MEDGEN:825921",
          "NCIT:C6358",
          "Orphanet:363489",
          "SCTID:702406000",
          "UMLS:C3840076"
        ],
        "synonyms": [
          "sex cord-stromal tumor of testis",
          "sex cord-stromal tumour of testis",
          "testicular sex cord-stromal neoplasm",
          "testicular sex cord-stromal tumor",
          "testicular sex cord-stromal tumour",
          "testis sex cord-stromal tumor",
          "testis sex cord-stromal tumour",
          "sex cord-stromal neoplasm",
          "sex cord-stromal neoplasm of testis",
          "sex cord-stromal neoplasm of the testis",
          "sex cord-stromal tumor of the testis",
          "sex cord-stromal tumour of the testis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant tumor that arises from the testis. It is composed of granulosa cells, Leydig cells, Sertoli cells, and fibroblasts. Each of these cell types may constitute the only cellular component that is present in the tumor or it may be mixed with other cell types in various combinations. The prognosis can not always be predicted on histologic grounds alone. Approximately, ten percent of these tumors may metastasize. Representative examples include granulosa cell tumor, Leydig cell tumor, Sertoli cell tumor, and tumors of the thecoma-fibroma group."
      },
      "child_count": 20,
      "reference_id": "MONDO:0003125"
    }
  ],
  "children": [
    {
      "id": 20209,
      "label": "benign testicular sertoli cell tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20205,
        20206,
        20570
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025256",
          "MEDGEN:231945",
          "NCIT:C6522",
          "UMLS:C1332540"
        ],
        "synonyms": [
          "benign sertoli cell neoplasm of testis",
          "benign sertoli cell neoplasm of the testis",
          "benign sertoli cell tumor of testis",
          "benign sertoli cell tumor of the testis",
          "benign sertoli cell tumour of testis",
          "benign sertoli cell tumour of the testis",
          "benign testicular sertoli cell neoplasm",
          "benign testicular sertoli cell tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-metastasizing sex cord-stromal tumor that arises from the testis. Morphologically, it is characterized by the presence of Sertoli cells forming tubules. Leydig cells are rare or absent."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020813"
    }
  ],
  "roots": [
    {
      "id": 4740,
      "label": "Sertoli cell tumor"
    },
    {
      "id": 5102,
      "label": "testicular sex cord-stromal neoplasm"
    }
  ]
}