{
  "id": 20285,
  "label": "pancreatic neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021040",
  "properties": {
    "xrefs": [
      "EFO:0003860",
      "MEDGEN:18279",
      "MESH:D010190",
      "NCIT:C3305",
      "ONCOTREE:PANCREAS",
      "SCTID:126859007",
      "UMLS:C0030297"
    ],
    "synonyms": [
      "neoplasm of pancreas",
      "neoplasm of the pancreas",
      "pancreas neoplasm",
      "pancreas neoplasm (disease)",
      "pancreas tumor",
      "pancreas tumour",
      "pancreatic neoplasm",
      "pancreatic tumor",
      "pancreatic tumour",
      "tumor of pancreas",
      "tumor of the pancreas",
      "tumour of pancreas",
      "tumour of the pancreas",
      "pancreas"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A benign or malignant neoplasm involving the pancreas."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 4455,
      "label": "pancreas disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6151,
        6875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:26",
          "EFO:0009605",
          "ICD10CM:K86.9",
          "ICD9:577.8",
          "ICD9:577.9",
          "MEDGEN:14583",
          "MESH:D010182",
          "NCIT:C26842",
          "SCTID:3855007",
          "UMLS:C0030286",
          "icd11.foundation:1726554290"
        ],
        "synonyms": [
          "disease of pancreas",
          "disease or disorder of pancreas",
          "disorder of pancreas",
          "pancreas disease",
          "pancreas disease or disorder",
          "pancreatic disorder",
          "disease, pancreatic",
          "diseases, pancreatic",
          "pancreatic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002356"
    },
    {
      "id": 20434,
      "label": "digestive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0008549",
          "MEDGEN:8398",
          "MESH:D005770",
          "NCIT:C3052",
          "UMLS:C0012243"
        ],
        "synonyms": [
          "GI neoplasm",
          "GI system neoplasm",
          "GI system tumor",
          "GI system tumour",
          "GI tumor",
          "GI tumour",
          "digestive neoplasm",
          "digestive system neoplasm (disease)",
          "digestive system tumor",
          "digestive system tumour",
          "digestive tumor",
          "digestive tumour",
          "gastrointestinal neoplasm",
          "gastrointestinal system neoplasm",
          "gastrointestinal system tumor",
          "gastrointestinal system tumour",
          "gastrointestinal tumor",
          "gastrointestinal tumour",
          "neoplasm of GI system",
          "neoplasm of digestive system",
          "neoplasm of gastrointestinal system",
          "neoplasm of the GI system",
          "neoplasm of the digestive system",
          "neoplasm of the gastrointestinal system",
          "tumor of GI system",
          "tumor of digestive system",
          "tumor of gastrointestinal system",
          "tumor of the GI system",
          "tumor of the digestive system",
          "tumor of the gastrointestinal system",
          "tumour of GI system",
          "tumour of digestive system",
          "tumour of gastrointestinal system",
          "tumour of the GI system",
          "tumour of the digestive system",
          "tumour of the gastrointestinal system"
        ],
        "definition": "A neoplasm (disease) that involves the digestive system."
      },
      "child_count": 23,
      "reference_id": "MONDO:0021223"
    }
  ],
  "children": [
    {
      "id": 7431,
      "label": "pancreatic neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4104,
        20285,
        21456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1799",
          "EFO:0007331",
          "GARD:0022052",
          "ICDO:8150/1",
          "MEDGEN:1848937",
          "NCIT:C27031",
          "Orphanet:506052",
          "SCTID:254611009",
          "UMLS:C5848399",
          "icd11.foundation:1421495979"
        ],
        "synonyms": [
          "PNEN",
          "endocrine pancreas neoplasm",
          "endocrine pancreas neoplasm (disease)",
          "endocrine pancreas tumor",
          "endocrine pancreas tumour",
          "neoplasm of endocrine pancreas",
          "pancreatic NEN",
          "pancreatic endocrine neoplasm",
          "pancreatic neuroendocrine neoplasm",
          "tumor of endocrine pancreas",
          "tumour of endocrine pancreas",
          "Islet cell tumors",
          "Islet cell tumours",
          "endocrine pancreas cancer",
          "islet cell neoplasm",
          "islet cell tumor",
          "islet cell tumour",
          "malignant pancreatic endocrine tumor",
          "malignant pancreatic endocrine tumour",
          "Islet of Langerhans tumor",
          "Islet of Langerhans tumour",
          "neuroendocrine neoplasm of pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the pancreas. It includes neuroendocrine tumors (low and intermediate grade) and neuroendocrine carcinomas (high grade)."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005815"
    },
    {
      "id": 11035,
      "label": "malignant pancreatic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4587,
        20285
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1793",
          "EFO:1000359",
          "GARD:0027792",
          "ICD10CM:C25",
          "ICD9:157.0",
          "ICD9:157.1",
          "ICD9:157.2",
          "ICD9:157.8",
          "MEDGEN:138068",
          "NCIT:C9005",
          "UMLS:C0346647",
          "icd11.foundation:542147910"
        ],
        "synonyms": [
          "pancreas neoplasm",
          "cancer of pancreas",
          "malignant neoplasm of pancreas",
          "malignant neoplasm of the pancreas",
          "malignant pancreas neoplasm",
          "malignant pancreatic neoplasm",
          "pancreas cancer",
          "pancreatic cancer",
          "pancreatic tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the pancreas."
      },
      "child_count": 8,
      "reference_id": "MONDO:0009831"
    },
    {
      "id": 18586,
      "label": "GCGR-related hyperglucagonemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5714,
        20285
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0112306",
          "GARD:0010460",
          "MEDGEN:1677024",
          "OMIM:619290",
          "Orphanet:438274",
          "UMLS:C4763635"
        ],
        "synonyms": [
          "MVAH",
          "Mahvash disease",
          "alpha-cell hyperplasia with glucagonemia",
          "nesidioblastosis alpha cell hyperplasia microglucagonoma and nonfunctioning islet cell tumor",
          "nesidioblastosis alpha cell hyperplasia microglucagonoma and nonfunctioning islet cell tumour",
          "nesidioblastosis, alpha cell hyperplasia, microglucagonoma, and nonfunctioning islet cell tumor",
          "nesidioblastosis, alpha cell hyperplasia, microglucagonoma, and nonfunctioning islet cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare tumor of pancreas caused by mutations in the GCGR gene characterized by pancreatic alpha cell hyperplasia, pancreatic neuroendocrine tumors and markedly increased serum glucagon levels in the absence of a glucagonoma syndrome. Clinical manifestations may include abdominal pain, pancreatitis, fatigue, diarrhea, and diabetes mellitus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018582"
    },
    {
      "id": 19454,
      "label": "adenoma of pancreas",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6714,
        20285
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0004204",
          "MEDGEN:256157",
          "MESH:C538110",
          "MedDRA:10058902",
          "Orphanet:93292",
          "SCTID:208061000119101",
          "UMLS:C1142432"
        ],
        "synonyms": [
          "pancreatic adenoma",
          "adenoma of the pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0019668"
    },
    {
      "id": 20317,
      "label": "pancreatic exocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20285
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:235.5",
          "MEDGEN:138030",
          "NCIT:C4445",
          "SCTID:254604005",
          "UMLS:C0345920"
        ],
        "synonyms": [
          "exocrine pancreas neoplasm",
          "exocrine pancreas neoplasm (disease)",
          "exocrine pancreas tumor",
          "exocrine pancreas tumour",
          "neoplasm of exocrine pancreas",
          "neoplasm of the exocrine pancreas",
          "pancreatic exocrine neoplasm",
          "pancreatic exocrine tumor",
          "pancreatic exocrine tumour",
          "tumor of exocrine pancreas",
          "tumor of the exocrine pancreas",
          "tumour of exocrine pancreas",
          "tumour of the exocrine pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that arises from the epithelial cells of the exocrine pancreatic tissue."
      },
      "child_count": 5,
      "reference_id": "MONDO:0021076"
    },
    {
      "id": 20591,
      "label": "benign neoplasm of pancreas",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2884,
        20285
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:D13.6",
          "MEDGEN:91126",
          "NCIT:C4612",
          "SCTID:92264007",
          "UMLS:C0347284",
          "icd11.foundation:1870352651"
        ],
        "synonyms": [
          "benign neoplasm of the pancreas",
          "benign pancreas neoplasm",
          "benign pancreas tumor",
          "benign pancreas tumour",
          "benign pancreatic neoplasm",
          "benign pancreatic tumor",
          "benign pancreatic tumour",
          "benign tumor of pancreas",
          "benign tumor of the pancreas",
          "benign tumour of pancreas",
          "benign tumour of the pancreas",
          "pancreas benign neoplasm",
          "pancreas neoplasm, benign",
          "pancreas tumor, benign",
          "pancreatic neoplasm, benign",
          "pancreatic tumor, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the pancreas."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021470"
    },
    {
      "id": 22791,
      "label": "intraductal tubulopapillary neoplasm of pancreas",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20285
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022331",
          "MEDGEN:459415",
          "NCIT:C95506",
          "Orphanet:580572",
          "UMLS:C2987189"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0034987"
    }
  ],
  "roots": [
    {
      "id": 4455,
      "label": "pancreas disorder"
    },
    {
      "id": 20434,
      "label": "digestive system neoplasm"
    }
  ]
}