{
  "id": 20291,
  "label": "breast phyllodes tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021047",
  "properties": {
    "xrefs": [
      "GARD:0025279",
      "MEDGEN:65943",
      "NCIT:C7575",
      "ONCOTREE:PT",
      "SCTID:712989008",
      "UMLS:C0238031"
    ],
    "synonyms": [
      "breast cystosarcoma phyllodes",
      "breast phyllodes neoplasm",
      "breast phyllodes tumor",
      "cystosarcoma phyllodes of breast",
      "cystosarcoma phyllodes of the breast",
      "cystosarcoma phylloides - breast",
      "cystosarcoma phylloides of the breast",
      "phyllodes breast neoplasm",
      "phyllodes breast tumor",
      "phyllodes breast tumour",
      "phyllodes neoplasm of breast",
      "phyllodes neoplasm of the breast",
      "phyllodes tumor of breast",
      "phyllodes tumor of the breast",
      "phyllodes tumour of breast",
      "phyllodes tumour of the breast"
    ],
    "categories": [
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A benign, malignant, or borderline circumscribed biphasic neoplasm that arises from the breast. It usually affects middle-aged women. It is characterized by the presence of a double layer of epithelial cells that are arranged in clefts, surrounded by a spindle cell mesenchymal (stromal) component."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6806,
      "label": "phyllodes tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20289
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000653",
          "MEDGEN:1209",
          "MESH:D003557",
          "NCIT:C2977",
          "UMLS:C0010701"
        ],
        "synonyms": [
          "CSP",
          "cystosarcoma phyllodes",
          "phyllodes neoplasm",
          "phyllodes tumor"
        ],
        "definition": "A benign, borderline, or malignant fibroepithelial neoplasm arising from the breast and rarely the prostate gland. It may recur following resection. The recurrence rates are higher for borderline and malignant phyllodes tumors. In borderline and malignant phyllodes tumors metastases to distant anatomic sites can occur. The incidence of metastases is higher in malignant phyllodes tumors."
      },
      "child_count": 4,
      "reference_id": "MONDO:0005078"
    },
    {
      "id": 20290,
      "label": "breast fibroepithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20289,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:267408",
          "NCIT:C40405",
          "ONCOTREE:BFN",
          "UMLS:C1511309"
        ],
        "synonyms": [
          "breast fibroepithelial neoplasm",
          "breast fibroepithelial tumor",
          "breast fibroepithelial tumour",
          "BFN",
          "breast fibroepithelial neoplasms"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant biphasic neoplasm that arises from the breast parenchyma. It is characterized by the presence of an epithelial and a mesenchymal (stromal) component. The typical examples are fibroadenoma and phyllodes tumor."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021046"
    }
  ],
  "children": [
    {
      "id": 4568,
      "label": "malignant breast phyllodes tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8659,
        20291,
        22955
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3016",
          "EFO:0008545",
          "GARD:0023148",
          "MEDGEN:87543",
          "NCIT:C4504",
          "ONCOTREE:MPT",
          "SCTID:254844000",
          "UMLS:C0346154",
          "icd11.foundation:147026376"
        ],
        "synonyms": [
          "malignant phyllodes neoplasm",
          "phyllodes breast neoplasm",
          "phyllodes breast tumor",
          "phyllodes breast tumour",
          "phyllodes tumor, malignant (morphologic abnormality)",
          "breast phyllodes tumor, malignant",
          "malignant breast phyllodes neoplasm",
          "malignant breast phyllodes tumor",
          "malignant cystosarcoma phyllodes of breast",
          "malignant cystosarcoma phyllodes of the breast",
          "malignant mammary phyllodes neoplasm",
          "malignant mammary phyllodes tumor",
          "malignant phyllodes breast neoplasm",
          "malignant phyllodes neoplasm of breast",
          "malignant phyllodes neoplasm of the breast",
          "malignant phyllodes tumor (morphologic abnormality)",
          "malignant phyllodes tumor of breast",
          "malignant phyllodes tumor of the breast",
          "malignant phyllodes tumour (morphologic abnormality)",
          "malignant phyllodes tumour of breast",
          "malignant phyllodes tumour of the breast",
          "breast malignant phyllodes tumor",
          "breast malignant phyllodes tumour",
          "malignant cystosarcoma phyllodes",
          "malignant cystosarcoma phyllodes (morphologic abnormality)",
          "malignant phyllodes tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A phyllodes tumor of the breast characterized by infiltrative margins and a sarcomatous stromal component. The sarcomatous stroma usually displays features of fibrosarcoma. Liposarcomatous, osteosarcomatous, or rhabdomyosarcomatous elements may also be present."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002489"
    },
    {
      "id": 16598,
      "label": "benign breast phyllodes tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027,
        20291,
        22954
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1631",
          "GARD:0009514",
          "MEDGEN:231438",
          "MedDRA:10011813",
          "NCIT:C5196",
          "ONCOTREE:BPT",
          "Orphanet:180261",
          "SCTID:720344007",
          "UMLS:C1332533",
          "icd11.foundation:827143668"
        ],
        "synonyms": [
          "benign phyllodes neoplasm",
          "phyllodes neoplasm",
          "phyllodes tumor, benign (morphologic abnormality)",
          "benign breast phyllodes tumor",
          "benign phyllodes neoplasm of breast",
          "benign phyllodes neoplasm of the breast",
          "benign phyllodes tumor of breast",
          "benign phyllodes tumor of the breast",
          "benign phyllodes tumour of breast",
          "benign phyllodes tumour of the breast",
          "breast benign phyllodes neoplasm",
          "breast phyllodes tumor, benign",
          "cystosarcoma phyllode of the breast",
          "cystosarcoma phylloide of the breast",
          "phylloide tumor of the breast",
          "phylloide tumour of the breast",
          "BPT",
          "benign cystosarcoma phyllodes",
          "cystosarcoma phyllode",
          "cystosarcoma phyllodes",
          "cystosarcoma phyllodes NOS (morphologic abnormality)",
          "cystosarcoma phylloide",
          "phyllode tumor of the breast",
          "phyllode tumour of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A usually unilateral, benign and well circumscribed biphasic neoplasm that arises from the breast. It usually affects middle-aged women. It is characterized by the presence of a double layer of epithelial cells that are arranged in clefts, surrounded by a cellular, monomorphic spindle cell mesenchymal component. Mitoses are rare. Necrotic changes may be present in large tumors."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015871"
    }
  ],
  "roots": [
    {
      "id": 6806,
      "label": "phyllodes tumor"
    },
    {
      "id": 20290,
      "label": "breast fibroepithelial neoplasm"
    }
  ]
}