{
  "id": 20295,
  "label": "parasympathetic paraganglioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021052",
  "properties": {
    "xrefs": [
      "GARD:0025281",
      "ICDO:8682/1",
      "MEDGEN:90779",
      "NCIT:C4217",
      "UMLS:C0334416"
    ],
    "synonyms": [
      "paraganglioma of parasympathetic nervous system",
      "parasympathetic Extra-adrenal paraganglioma",
      "parasympathetic Paraganglionic neoplasm",
      "parasympathetic nervous system paraganglioma",
      "parasympathetic paraganglioma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A benign or malignant, usually non-functioning, extra-adrenal paraganglioma that arises from paraganglia located along the parasympathetic nerves. Representative examples include aorticopulmonary, carotid body, jugulotympanic, and mediastinal paragangliomas."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 2912,
      "label": "paraganglioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4464,
        19314,
        20691,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050773",
          "EFO:1000453",
          "GARD:0022770",
          "ICD9:239.7",
          "ICDO:8680/1",
          "MEDGEN:10571",
          "MESH:D010235",
          "NCIT:C3308",
          "ONCOTREE:PGNG",
          "SCTID:127027008",
          "UMLS:C0030421"
        ],
        "synonyms": [
          "Paraganglionic neoplasm",
          "Paraganglionic tumor",
          "Paraganglionic tumour",
          "neoplasm of paraganglion",
          "neoplasm of the paraganglion",
          "paraganglioma",
          "paragangliomas",
          "paraganglion neoplasm",
          "paraganglion tumor",
          "paraganglion tumour",
          "tumor of paraganglion",
          "tumor of the paraganglion",
          "tumour of paraganglion",
          "tumour of the paraganglion",
          "chemodectoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm arising from paraganglia located along the sympathetic or parasympathetic nerves. Infrequently, it may arise outside the usual distribution of the sympathetic and parasympathetic paraganglia. Tumors arising from the adrenal gland medulla are called pheochromocytomas. Morphologically, paragangliomas usually display a nesting (Zellballen) growth pattern. There are no reliable morphologic criteria to distinguish between benign and malignant paragangliomas. The only definitive indicator of malignancy is the presence of regional or distant metastases."
      },
      "child_count": 48,
      "reference_id": "MONDO:0000448"
    },
    {
      "id": 23498,
      "label": "parasympathetic nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3525
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:148205",
          "SCTID:46091002",
          "UMLS:C0750945"
        ],
        "synonyms": [
          "disease of parasympathetic nervous system",
          "disease or disorder of parasympathetic nervous system",
          "disorder of parasympathetic nervous system",
          "parasympathetic nervous system disease",
          "parasympathetic nervous system disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease or disorder that involves the parasympathetic nervous system."
      },
      "child_count": 1,
      "reference_id": "MONDO:0044995"
    }
  ],
  "children": [
    {
      "id": 20296,
      "label": "carotid body paraganglioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7791,
        20295
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010598",
          "ICDO:8692/1",
          "MEDGEN:2853",
          "MESH:D002345",
          "NCIT:C2932",
          "UMLS:C0007279"
        ],
        "synonyms": [
          "carotid body paraganglioma",
          "paraganglioma of carotid body",
          "carotid body chemodectoma",
          "carotid body tumor",
          "carotid body tumour",
          "chemodectoma",
          "chemodectoma, undetermined",
          "paraganglioma of the carotid body",
          "tumor of carotid body",
          "tumor of the carotid body",
          "tumour of carotid body",
          "tumour of the carotid body"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant extra-adrenal parasympathetic paraganglioma arising from paraganglia adjacent to or in the bifurcation of the common carotid artery. Most patients present with a slow growing, painless mass in the neck."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021053"
    },
    {
      "id": 20305,
      "label": "jugulotympanic paraganglioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4813,
        7791,
        20295,
        21247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025284",
          "ICD9:239.7",
          "ICDO:8690/1",
          "MEDGEN:4905",
          "NCIT:C3061",
          "SCTID:127030001",
          "UMLS:C0017671"
        ],
        "synonyms": [
          "basicranium parasympathetic paraganglioma",
          "glomus jugulare neoplasm",
          "glomus jugulare tumor",
          "glomus jugulare tumour",
          "jugular body neoplasm",
          "jugular body neoplasm (disease)",
          "jugular body tumor",
          "jugular body tumour",
          "jugular paraganglioma",
          "jugulotympanic paraganglioma",
          "neoplasm of glomus jugulare",
          "neoplasm of jugular body",
          "neoplasm of the glomus jugulare",
          "parasympathetic paraganglioma of basicranium",
          "tumor of glomus jugulare",
          "tumor of jugular body",
          "tumor of the glomus jugulare",
          "tumour of glomus jugulare",
          "tumour of jugular body",
          "tumour of the glomus jugulare",
          "Glomus tumor",
          "Glomus tumour",
          "Paraganglioma - glomus jugulare"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant extra-adrenal parasympathetic paraganglioma arising from paraganglia in the base of the skull and middle ear."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021064"
    },
    {
      "id": 20544,
      "label": "neoplasm of aortic body",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7210,
        20295,
        20321,
        20518,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025316",
          "ICD9:239.7",
          "ICDO:8691/1",
          "MEDGEN:87236",
          "NCIT:C4218",
          "SCTID:127029006",
          "UMLS:C0334417"
        ],
        "synonyms": [
          "aortic body neoplasm",
          "aortic body neoplasm (disease)",
          "aortic body paraganglioma",
          "aortic body tumor",
          "aortic body tumour",
          "aorticopulmonary paraganglioma",
          "neoplasm of aortic body",
          "neoplasm of the aortic body",
          "paraganglioma of aortic body",
          "paraganglioma of the aortic body",
          "tumor of aortic body",
          "tumor of the aortic body",
          "tumour of aortic body",
          "tumour of the aortic body"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant extra-adrenal parasympathetic paraganglioma that arises from paraganglia adjacent to the base of the heart and great vessels."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021389"
    },
    {
      "id": 23431,
      "label": "vagus nerve paraganglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3805,
        7791,
        20295
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0008620",
          "MEDGEN:141635",
          "NCIT:C8427",
          "SCTID:253030004",
          "UMLS:C0474819"
        ],
        "synonyms": [
          "paraganglioma of the vagal body",
          "paraganglioma of the vagus nerve",
          "paraganglioma of vagal body",
          "paraganglioma of vagus nerve",
          "vagal body paraganglioma",
          "vagal paraganglioma",
          "vagus nerve paraganglioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant extra-adrenal parasympathetic paraganglioma arising from paraganglia in the vagus nerve. Patients may present with a slow growing, painless mass in the neck, hoarseness, vocal cord paralysis, and dysphagia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044768"
    }
  ],
  "roots": [
    {
      "id": 2912,
      "label": "paraganglioma"
    },
    {
      "id": 23498,
      "label": "parasympathetic nervous system disorder"
    }
  ]
}