{
  "id": 20306,
  "label": "pleural neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021065",
  "properties": {
    "xrefs": [
      "MEDGEN:18523",
      "MESH:D010997",
      "NCIT:C3332",
      "ONCOTREE:PLEURA",
      "SCTID:126719004",
      "UMLS:C0032229"
    ],
    "synonyms": [
      "neoplasm of pleura",
      "neoplasm of pleural cavity",
      "neoplasm of the pleura",
      "pleura neoplasm",
      "pleura neoplasm (disease)",
      "pleura tumor",
      "pleura tumour",
      "pleural cavity neoplasm (disease)",
      "pleural cavity tumor",
      "pleural cavity tumour",
      "pleural neoplasm",
      "pleural tumor",
      "pleural tumour",
      "tumor of pleura",
      "tumor of the pleura",
      "tumour of pleura",
      "tumour of the pleura"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A benign or malignant neoplasm that involves the serous membrane that lines the lungs and thoracic cavity. Most pleural neoplasms are metastatic. Diffuse malignant mesothelioma is the most common primary malignant neoplasm of the pleura."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 4184,
      "label": "pleural disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2809
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1532",
          "ICD9:518.89",
          "MEDGEN:10804",
          "MESH:D010995",
          "NCIT:C26859",
          "SCTID:88075009",
          "UMLS:C0032226"
        ],
        "synonyms": [
          "disease of pleura",
          "disease or disorder of pleura",
          "disorder of pleura",
          "pleura disease",
          "pleura disease or disorder",
          "pleural disorder",
          "pleural disorders",
          "non-neoplastic pleural disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the pleura. Representative examples include pleural infection, pleural mesothelioma, and pleural solitary fibrous tumor."
      },
      "child_count": 5,
      "reference_id": "MONDO:0002037"
    },
    {
      "id": 20056,
      "label": "respiratory tract neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        6815
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003853",
          "ICD10CM:C30-C39",
          "MEDGEN:11200",
          "MESH:D012142",
          "NCIT:C3355",
          "SCTID:126667002",
          "UMLS:C0035244"
        ],
        "synonyms": [
          "neoplasm of respiratory tract",
          "neoplasm of the respiratory tract",
          "neoplasm, respiratory tract",
          "neoplasms, respiratory tract",
          "respiratory system neoplasm",
          "respiratory tract neoplasm",
          "respiratory tract tumor",
          "respiratory tract tumour",
          "tract neoplasm, respiratory",
          "tract neoplasms, respiratory",
          "tumor of respiratory tract",
          "tumor of the respiratory tract",
          "tumour of respiratory tract",
          "tumour of the respiratory tract"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm involving the respiratory tract."
      },
      "child_count": 16,
      "reference_id": "MONDO:0020641"
    }
  ],
  "children": [
    {
      "id": 5249,
      "label": "pleural mesothelioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6794,
        20306
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5157",
          "EFO:1000485",
          "HP:0100002",
          "ICD10CM:C45.0",
          "MEDGEN:237179",
          "NCIT:C9351",
          "ONCOTREE:PLMESO",
          "SCTID:109372009",
          "UMLS:C1377913"
        ],
        "synonyms": [
          "mesothelioma of pleura",
          "mesothelioma of the pleura",
          "pleura mesothelioma",
          "pleural mesothelioma",
          "pleural mesothelioma (disease)",
          "benign pleural mesothelioma",
          "pleural mesothelioma (disease), benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A neoplasm that arises from the mesothelial cells of the pleura. The primary cause is exposure to asbestos. The major histologic variants are the epithelioid malignant mesothelioma, desmoplastic malignant mesothelioma, and sarcomatoid malignant mesothelioma. Patients present with persistent cough and shortness of breath."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003308"
    },
    {
      "id": 5785,
      "label": "neurilemmoma of the pleura",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6580,
        20306
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6564",
          "GARD:0023739",
          "MEDGEN:233863",
          "NCIT:C5418",
          "UMLS:C1335435"
        ],
        "synonyms": [
          "neurilemmoma of pleura",
          "pleura schwannoma",
          "pleural neurilemmoma",
          "pleural schwannoma",
          "schwannoma of pleura",
          "schwannoma of the pleura"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A schwannoma that involves the pleura."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003926"
    },
    {
      "id": 7835,
      "label": "pleural cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        5215,
        20306
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5158",
          "EFO:1000362",
          "ICD10CM:C38.4",
          "ICD9:163",
          "ICD9:163.8",
          "ICD9:163.9",
          "MEDGEN:56307",
          "NCIT:C3547",
          "SCTID:363433009",
          "UMLS:C0153494"
        ],
        "synonyms": [
          "neoplasm of pleura",
          "pleural tumor",
          "pleural tumour",
          "cancer of pleura",
          "cancer of the pleura",
          "malignant neoplasm of pleura",
          "malignant neoplasm of the pleura",
          "malignant pleura neoplasm",
          "malignant pleural neoplasm",
          "malignant pleural tumor",
          "malignant pleural tumour",
          "malignant tumor of pleura",
          "malignant tumor of the pleura",
          "malignant tumour of pleura",
          "malignant tumour of the pleura",
          "pleura cancer",
          "pleural cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the pleura. A representative example of primary malignant pleural neoplasm is the malignant pleural mesothelioma. A representative example of metastatic malignant neoplasm to the pleura is metastatic carcinoma that has spread to the pleura from another anatomic site."
      },
      "child_count": 12,
      "reference_id": "MONDO:0006294"
    },
    {
      "id": 20286,
      "label": "pleural solitary fibrous tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16812,
        20306
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025278",
          "NCIT:C4457",
          "SCTID:254646001"
        ],
        "synonyms": [
          "fibroma of pleura",
          "fibroma of the pleura",
          "localised fibrous mesothelioma of pleura",
          "localised fibrous mesothelioma of the pleura",
          "localized fibrous mesothelioma of pleura",
          "localized fibrous mesothelioma of the pleura",
          "pleura solitary fibrous tumor",
          "pleura solitary fibrous tumour",
          "pleural Submesothelial fibroma",
          "pleural cavity solitary fibrous tumor",
          "pleural cavity solitary fibrous tumour",
          "pleural fibroma",
          "pleural solitary fibrous tumor",
          "solitary fibrous tumor of pleura",
          "solitary fibrous tumor of the pleura",
          "solitary fibrous tumour of pleura",
          "solitary fibrous tumour of the pleura"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A localized neoplasm of probable fibroblastic derivation, that arises from the pleura. It is characterized by the presence of round to spindle-shaped cells, hylanized stroma formation, thin-walled branching blood vessels, and thin bands of collagen."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021041"
    },
    {
      "id": 20579,
      "label": "benign neoplasm of pleura",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2881,
        20306
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:212.4",
          "MEDGEN:57806",
          "NCIT:C3603",
          "SCTID:92298003",
          "UMLS:C0153955",
          "icd11.foundation:2142393865"
        ],
        "synonyms": [
          "benign neoplasm of the pleura",
          "benign pleural neoplasm",
          "benign pleural tumor",
          "benign pleural tumour",
          "benign tumor of pleura",
          "benign tumor of the pleura",
          "benign tumour of pleura",
          "benign tumour of the pleura",
          "pleura benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the pleura."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021457"
    }
  ],
  "roots": [
    {
      "id": 4184,
      "label": "pleural disorder"
    },
    {
      "id": 20056,
      "label": "respiratory tract neoplasm"
    }
  ]
}