{
  "id": 20307,
  "label": "urinary system neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021066",
  "properties": {
    "xrefs": [
      "ICD9:239.5",
      "MEDGEN:52949",
      "NCIT:C192666",
      "NCIT:C3431",
      "ONCOTREE:BLADDER",
      "SCTID:126879004",
      "UMLS:C0042076"
    ],
    "synonyms": [
      "neoplasm of renal system",
      "neoplasm of the urinary system",
      "neoplasm of the urinary tract",
      "neoplasm of urinary system",
      "neoplasm of urinary tract",
      "renal system neoplasm",
      "renal system neoplasm (disease)",
      "renal system tumor",
      "renal system tumour",
      "tumor of renal system",
      "tumor of the urinary system",
      "tumor of the urinary tract",
      "tumor of urinary system",
      "tumor of urinary tract",
      "tumour of renal system",
      "tumour of the urinary system",
      "tumour of the urinary tract",
      "tumour of urinary system",
      "tumour of urinary tract",
      "urinary system neoplasm",
      "urinary system tumor",
      "urinary system tumour",
      "urinary tract neoplasm",
      "urinary tract tumor",
      "urinary tract tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A benign or malignant, primary or metastatic neoplasm involving the urinary system. --2003"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 4253,
      "label": "urinary system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:18",
          "EFO:0009690",
          "ICD9:V47.4",
          "MEDGEN:21791",
          "MESH:D014570",
          "NCIT:C3430",
          "SCTID:128606002",
          "UMLS:C0042075"
        ],
        "synonyms": [
          "disease of renal system",
          "disease or disorder of renal system",
          "disease, urinary tract",
          "disease, urologic",
          "disease, urological",
          "diseases, urinary tract",
          "diseases, urologic",
          "diseases, urological",
          "disorder of renal system",
          "disorder of the urinary system",
          "disorder of urinary system",
          "renal system disease",
          "renal system disease or disorder",
          "urinary disease",
          "urinary system disorder",
          "urinary tract disease",
          "urinary tract diseases",
          "urinary tract disorder",
          "urologic disease",
          "urologic disorder",
          "urological disease",
          "urological diseases",
          "urological disorder",
          "urological disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disease involving the renal system."
      },
      "child_count": 20,
      "reference_id": "MONDO:0002118"
    },
    {
      "id": 6798,
      "label": "neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21214
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14566",
          "EFO:0000616",
          "HP:0002664",
          "ICD10CM:C00-D49",
          "ICD10CM:C7A-C7A",
          "ICD10CM:C7B-C7B",
          "ICD9:140-239",
          "ICD9:239.8",
          "ICD9:239.9",
          "MEDGEN:10294",
          "MESH:D009369",
          "NCIT:C3262",
          "ONCOTREE:OTHER",
          "SCTID:55342001",
          "UMLS:C0027651"
        ],
        "synonyms": [
          "cell process disease",
          "disease of cellular proliferation",
          "neoplasia",
          "neoplasm",
          "neoplasm (disease)",
          "neoplastic disease",
          "neoplastic growth",
          "tumor",
          "tumor disease",
          "tumour",
          "tumour disease",
          "other neoplasm"
        ],
        "definition": "A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005070"
    }
  ],
  "children": [
    {
      "id": 6002,
      "label": "benign urinary system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        20307
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:731",
          "ICD9:223.89",
          "ICD9:223.9",
          "MEDGEN:146348",
          "MESH:D014571",
          "NCIT:C192667",
          "NCIT:C4893",
          "SCTID:92468007",
          "UMLS:C0686167"
        ],
        "synonyms": [
          "neoplasm of urinary system",
          "tumor of the urinary system",
          "tumor of urinary tract",
          "tumour of the urinary system",
          "tumour of urinary tract",
          "urinary tract neoplasm",
          "benign neoplasm of the urinary tract",
          "benign neoplasm of urinary tract",
          "benign tumor of the urinary tract",
          "benign tumor of urinary tract",
          "benign tumour of the urinary tract",
          "benign tumour of urinary tract",
          "benign urinary system neoplasm",
          "benign urinary tract neoplasm",
          "benign urinary tract tumor",
          "benign urinary tract tumour",
          "renal system benign neoplasm",
          "urinary system benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm that arises from the organs that comprise the urinary system. Representative examples include renal oncocytoma, bladder inverted papilloma, and urothelial papilloma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0004180"
    },
    {
      "id": 6728,
      "label": "urinary bladder neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7612,
        20307
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000294",
          "ICD9:239.4",
          "MEDGEN:594",
          "NCIT:C2901",
          "SCTID:126885006",
          "UMLS:C0005695"
        ],
        "synonyms": [
          "bladder neoplasm",
          "bladder tumor",
          "bladder tumors",
          "bladder tumour",
          "bladder tumours",
          "neoplasm of bladder",
          "neoplasm of the bladder",
          "neoplasm of the urinary bladder",
          "neoplasm of urinary bladder",
          "tumor of bladder",
          "tumor of the bladder",
          "tumor of the urinary bladder",
          "tumor of urinary bladder",
          "tumour of bladder",
          "tumour of the bladder",
          "tumour of the urinary bladder",
          "tumour of urinary bladder",
          "urinary bladder neoplasm",
          "urinary bladder neoplasm (disease)",
          "urinary bladder neoplasms",
          "urinary bladder tumor",
          "urinary bladder tumors",
          "urinary bladder tumour",
          "urinary bladder tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm of the bladder. - 2003"
      },
      "child_count": 12,
      "reference_id": "MONDO:0004987"
    },
    {
      "id": 7836,
      "label": "malignant urinary system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        20307
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3996",
          "EFO:1000363",
          "ICD10CM:C64-C68",
          "ICD9:189.9",
          "MEDGEN:738719",
          "NCIT:C192668",
          "NCIT:C9297",
          "SCTID:448233000",
          "UMLS:C1644719"
        ],
        "synonyms": [
          "cancer of renal system",
          "malignant neoplasm of renal system",
          "malignant renal system neoplasm",
          "malignant urinary system neoplasm",
          "malignant urinary tract neoplasm",
          "renal system cancer",
          "urinary system cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant tumor involving the urinary system. Common tumor types include carcinomas, lymphomas, and sarcomas."
      },
      "child_count": 20,
      "reference_id": "MONDO:0006295"
    },
    {
      "id": 20342,
      "label": "prostate phyllodes tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6806,
        20307,
        20463
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009404",
          "MEDGEN:233326",
          "NCIT:C7574",
          "Orphanet:498228",
          "UMLS:C1335409"
        ],
        "synonyms": [
          "cystosarcoma phyllodes of prostate",
          "cystosarcoma phyllodes of the prostate",
          "phyllodes neoplasm of prostate",
          "phyllodes neoplasm of the prostate",
          "phyllodes tumor of prostate",
          "phyllodes tumor of the prostate",
          "phyllodes tumour of prostate",
          "phyllodes tumour of the prostate",
          "prostate cystosarcoma phyllodes",
          "prostate gland phyllodes tumor",
          "prostate gland phyllodes tumour",
          "prostate phyllodes neoplasm",
          "prostate phyllodes tumor",
          "malignant phyllodes tumor of prostate (subtype)",
          "malignant phyllodes tumour of prostate (subtype)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An unusual, biphasic benign or malignant neoplasm that arises from the prostate gland. It is characterized by the presence of an epithelial glandular component and a proliferating stroma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021102"
    },
    {
      "id": 20350,
      "label": "ureter neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4098,
        20307
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003844",
          "ICD9:239.5",
          "MEDGEN:12011",
          "NCIT:C3427",
          "SCTID:126882009",
          "UMLS:C0041955"
        ],
        "synonyms": [
          "neoplasm of the ureter",
          "neoplasm of ureter",
          "neoplasms of the ureter",
          "neoplasms of ureter",
          "tumor of the ureter",
          "tumor of ureter",
          "tumour of the ureter",
          "tumour of ureter",
          "ureter neoplasm",
          "ureter neoplasm (disease)",
          "ureter tumor",
          "ureter tumour",
          "ureteral neoplasm",
          "ureteral tumor",
          "ureteral tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the ureter."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021111"
    },
    {
      "id": 20396,
      "label": "kidney neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        20307
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003865",
          "ICD9:239.5",
          "MEDGEN:5967",
          "NCIT:C3150",
          "ONCOTREE:KIDNEY",
          "SCTID:126880001",
          "UMLS:C0022665"
        ],
        "synonyms": [
          "kidney neoplasm",
          "kidney neoplasm (disease)",
          "kidney tumor",
          "kidney tumour",
          "neoplasm of kidney",
          "neoplasm of the kidney",
          "renal neoplasm",
          "renal tumor",
          "renal tumors",
          "renal tumour",
          "renal tumours",
          "tumor of kidney",
          "tumor of the kidney",
          "tumour of kidney",
          "tumour of the kidney"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma."
      },
      "child_count": 16,
      "reference_id": "MONDO:0021163"
    },
    {
      "id": 20448,
      "label": "urethra neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6006,
        20307
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003846",
          "MEDGEN:12014",
          "NCIT:C3428",
          "UMLS:C0041971"
        ],
        "synonyms": [
          "neoplasm of the urethra",
          "neoplasm of urethra",
          "neoplasms. urethra",
          "tumor of the urethra",
          "tumor of urethra",
          "tumors. urethra",
          "tumour of the urethra",
          "tumour of urethra",
          "urethra neoplasm (disease)",
          "urethra neoplasms",
          "urethra tumor",
          "urethra tumors",
          "urethra tumour",
          "urethra tumours",
          "urethral neoplasm",
          "urethral neoplasms",
          "urethral tumor",
          "urethral tumors",
          "urethral tumour",
          "urethral tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the urethra."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021239"
    },
    {
      "id": 21366,
      "label": "urothelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20307,
        22962
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:275551",
          "NCIT:C39852",
          "UMLS:C1519840"
        ],
        "synonyms": [
          "neoplasm of urothelium",
          "transitional cell neoplasm of the urinary tract",
          "tumor of urothelium",
          "tumour of urothelium",
          "urothelial neoplasm",
          "urothelium neoplasm",
          "urothelium neoplasm (disease)",
          "urothelium tumor",
          "urothelium tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A neoplasm involving a urothelium."
      },
      "child_count": 10,
      "reference_id": "MONDO:0024337"
    }
  ],
  "roots": [
    {
      "id": 4253,
      "label": "urinary system disorder"
    },
    {
      "id": 6798,
      "label": "neoplasm"
    }
  ]
}