{
  "id": 20320,
  "label": "childhood neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021079",
  "properties": {
    "xrefs": [
      "MEDGEN:237153",
      "NCIT:C6283",
      "UMLS:C1368871"
    ],
    "synonyms": [
      "childhood neoplasm",
      "childhood neoplasm (disease)",
      "childhood tumor",
      "childhood tumour",
      "neoplasm (disease) of childhood",
      "paediatric neoplasm",
      "paediatric neoplasm (disease)",
      "paediatric tumour",
      "pediatric neoplasm",
      "pediatric neoplasm (disease)",
      "pediatric tumor"
    ],
    "definition": "A benign or malignant neoplasm arising during childhood."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 14,
  "parents": [
    {
      "id": 6798,
      "label": "neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21214
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14566",
          "EFO:0000616",
          "HP:0002664",
          "ICD10CM:C00-D49",
          "ICD10CM:C7A-C7A",
          "ICD10CM:C7B-C7B",
          "ICD9:140-239",
          "ICD9:239.8",
          "ICD9:239.9",
          "MEDGEN:10294",
          "MESH:D009369",
          "NCIT:C3262",
          "ONCOTREE:OTHER",
          "SCTID:55342001",
          "UMLS:C0027651"
        ],
        "synonyms": [
          "cell process disease",
          "disease of cellular proliferation",
          "neoplasia",
          "neoplasm",
          "neoplasm (disease)",
          "neoplastic disease",
          "neoplastic growth",
          "tumor",
          "tumor disease",
          "tumour",
          "tumour disease",
          "other neoplasm"
        ],
        "definition": "A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005070"
    }
  ],
  "children": [
    {
      "id": 4578,
      "label": "childhood astrocytic tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20320,
        20692
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3079",
          "GARD:0023152",
          "MEDGEN:272112",
          "NCIT:C9022",
          "UMLS:C1321865"
        ],
        "synonyms": [
          "astrocytic tumor",
          "astrocytic tumour",
          "astrocytic tumor of childhood",
          "astrocytic tumors, childhood",
          "astrocytic tumour of childhood",
          "childhood astrocytic neoplasm",
          "childhood astrocytic tumor",
          "juvenile astrocytoma",
          "juvenile astrocytoma (morphologic abnormality)",
          "paediatric astrocytic neoplasm",
          "paediatric astrocytic tumour",
          "paediatric astrocytoma",
          "pediatric astrocytic neoplasm",
          "pediatric astrocytic tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An astrocytic tumor appearing before the age of twenty one without designation of benign or malignant nor designated location."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002505"
    },
    {
      "id": 4755,
      "label": "childhood spinal cord tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20320,
        20444
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3637",
          "MEDGEN:209512",
          "NCIT:C9234",
          "UMLS:C1134515"
        ],
        "synonyms": [
          "childhood spinal cord neoplasm",
          "paediatric spinal cord neoplasm",
          "pediatric spinal cord neoplasm",
          "spinal cord neoplasm of childhood"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the spinal cord during childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002716"
    },
    {
      "id": 4767,
      "label": "childhood kidney neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20320,
        20396
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3675",
          "MEDGEN:232356",
          "NCIT:C6563",
          "UMLS:C1333003"
        ],
        "synonyms": [
          "kidney neoplasm",
          "childhood kidney neoplasm",
          "childhood kidney tumor",
          "childhood kidney tumour",
          "childhood renal neoplasm",
          "childhood renal tumor",
          "childhood renal tumour",
          "kidney neoplasm of childhood",
          "paediatric kidney neoplasm",
          "paediatric kidney tumour",
          "paediatric renal neoplasm",
          "paediatric renal tumour",
          "pediatric kidney neoplasm",
          "pediatric kidney tumor",
          "pediatric renal neoplasm",
          "pediatric renal tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A kidney neoplasm that occurs during childhood."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002730"
    },
    {
      "id": 4922,
      "label": "childhood infratentorial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20320,
        22967
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4207",
          "MEDGEN:232349",
          "NCIT:C5802",
          "UMLS:C1332973"
        ],
        "synonyms": [
          "childhood infratentorial neoplasm",
          "childhood infratentorial neoplasms",
          "childhood infratentorial tumor",
          "childhood infratentorial tumors",
          "childhood infratentorial tumour",
          "childhood infratentorial tumours",
          "infratentorial neoplasm of childhood",
          "paediatric infratentorial neoplasm",
          "paediatric infratentorial tumour",
          "pediatric infratentorial neoplasm",
          "pediatric infratentorial tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neoplasm that affects the infratentorial region of the brain and occurs during childhood."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002915"
    },
    {
      "id": 5047,
      "label": "pediatric meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17113,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4593",
          "GARD:0023350",
          "MEDGEN:79156",
          "NANDO:2200094",
          "NCIT:C8264",
          "UMLS:C0280656"
        ],
        "synonyms": [
          "meningioma",
          "childhood meningioma",
          "childhood meningioma (disease)",
          "meningioma (disease) of childhood",
          "paediatric meningioma (disease)",
          "pediatric meningioma",
          "pediatric meningioma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that occurs during childhood."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003057"
    },
    {
      "id": 5082,
      "label": "childhood mediastinal neurogenic neoplasm",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5083,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4690",
          "MEDGEN:234134",
          "NCIT:C5429",
          "UMLS:C1332981"
        ],
        "synonyms": [
          "childhood mediastinal neurogenic neoplasm",
          "childhood mediastinal neurogenic tumor",
          "childhood neurogenic neoplasm of mediastinum",
          "childhood neurogenic neoplasm of the mediastinum",
          "childhood neurogenic tumor of mediastinum",
          "childhood neurogenic tumor of the mediastinum",
          "childhood neurogenic tumour of mediastinum",
          "childhood neurogenic tumour of the mediastinum",
          "paediatric mediastinal neurogenic neoplasm",
          "paediatric mediastinal neurogenic tumour",
          "paediatric neurogenic neoplasm of mediastinum",
          "paediatric neurogenic neoplasm of the mediastinum",
          "paediatric neurogenic tumour of the mediastinum",
          "pediatric mediastinal neurogenic neoplasm",
          "pediatric mediastinal neurogenic tumor",
          "pediatric neurogenic neoplasm of mediastinum",
          "pediatric neurogenic neoplasm of the mediastinum",
          "pediatric neurogenic tumor of mediastinum",
          "pediatric neurogenic tumor of the mediastinum"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0003097"
    },
    {
      "id": 5400,
      "label": "childhood ependymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17161,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5509",
          "GARD:0023523",
          "MEDGEN:343609",
          "MESH:C531673",
          "NCIT:C8578",
          "UMLS:C1851584"
        ],
        "synonyms": [
          "ependymoma",
          "childhood ependymoma",
          "ependymoma of childhood",
          "paediatric ependymoma",
          "pediatric ependymoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An ependymoma that arises from the central nervous system and occurs during childhood."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003478"
    },
    {
      "id": 5631,
      "label": "childhood germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6773,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6053",
          "GARD:0023651",
          "MEDGEN:75907",
          "NCIT:C7928",
          "UMLS:C0279014"
        ],
        "synonyms": [
          "germ cell tumor",
          "germ cell tumour",
          "childhood germ cell neoplasm",
          "childhood germ cell tumor",
          "paediatric germ cell tumour",
          "pediatric germ cell neoplasm",
          "pediatric germ cell tumor",
          "paediatric germ cell cancer",
          "pediatric germ cell cancer"
        ],
        "definition": "A germ cell tumor that occurs during childhood."
      },
      "child_count": 8,
      "reference_id": "MONDO:0003751"
    },
    {
      "id": 5791,
      "label": "childhood optic nerve glioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5183,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6576",
          "GARD:0009309",
          "MEDGEN:124487",
          "NCIT:C7535",
          "UMLS:C0278653"
        ],
        "synonyms": [
          "visual pathway glioma",
          "childhood optic tract glioma",
          "childhood visual pathway glioma",
          "glioma of childhood visual pathway",
          "glioma of paediatric visual pathway",
          "glioma of pediatric visual pathway",
          "glioma of the childhood visual pathway",
          "glioma of the paediatric visual pathway",
          "glioma of the pediatric visual pathway",
          "optic nerve glioma of childhood",
          "paediatric optic nerve glioma",
          "paediatric optic tract glioma",
          "paediatric visual pathway glioma",
          "pediatric optic nerve glioma",
          "pediatric optic tract glioma",
          "pediatric visual pathway glioma",
          "visual pathway and hypothalamic glioma, childhood"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A glioma affecting the optic tract and occurring in childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003932"
    },
    {
      "id": 8005,
      "label": "childhood malignant neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000654",
          "MEDGEN:82962",
          "NCIT:C4005",
          "UMLS:C0278704"
        ],
        "synonyms": [
          "childhood cancer",
          "childhood malignant neoplasm",
          "childhood neoplasm, malignant",
          "malignant childhood neoplasm",
          "malignant childhood tumor",
          "malignant childhood tumour",
          "malignant paediatric neoplasm",
          "malignant paediatric tumour",
          "malignant pediatric neoplasm",
          "malignant pediatric tumor",
          "paediatric cancer",
          "pediatric cancer",
          "malignant neoplasm"
        ],
        "definition": "A malignant tumor that occurs in children. Representative examples include soft tissue and bone sarcomas (e.g. osteosarcoma) and embryonal neoplasms (e.g. hepatoblastoma and rhabdoid tumor)."
      },
      "child_count": 60,
      "reference_id": "MONDO:0006517"
    },
    {
      "id": 20921,
      "label": "childhood carcinoid tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7051,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009315",
          "MEDGEN:859267",
          "NCIT:C118810",
          "UMLS:C3899673"
        ],
        "synonyms": [
          "carcinoid tumor (disease) of childhood",
          "carcinoid tumour (disease) of childhood",
          "childhood carcinoid tumor",
          "childhood carcinoid tumor (disease)",
          "childhood carcinoid tumour (disease)",
          "paediatric carcinoid tumour (disease)",
          "pediatric carcinoid tumor (disease)",
          "carcinoid tumor childhood",
          "carcinoid tumour childhood"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare carcinoid tumor that occurs during childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022642"
    },
    {
      "id": 21583,
      "label": "childhood choroid plexus neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17175,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025460",
          "MEDGEN:76132",
          "NCIT:C42080",
          "UMLS:C0280623"
        ],
        "synonyms": [
          "choroid plexus neoplasm",
          "childhood choroid plexus neoplasm",
          "choroid plexus neoplasm of childhood",
          "paediatric choroid plexus neoplasm",
          "pediatric choroid plexus neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neoplasm that arises from the choroid plexus in the brain and occurs during childhood."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024744"
    },
    {
      "id": 22958,
      "label": "childhood testicular neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20320,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:272472",
          "NCIT:C5053",
          "UMLS:C1333010"
        ],
        "synonyms": [
          "childhood neoplasm of testis",
          "childhood neoplasm of the testis",
          "childhood testicular neoplasm",
          "neoplasm of testis of childhood",
          "paediatric neoplasm of testis",
          "paediatric neoplasm of the testis",
          "paediatric testicular neoplasm",
          "pediatric neoplasm of testis",
          "pediatric neoplasm of the testis",
          "pediatric testicular neoplasm",
          "testicular tumor, childhood"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm that arises from the testis during childhood."
      },
      "child_count": 2,
      "reference_id": "MONDO:0037250"
    },
    {
      "id": 23430,
      "label": "childhood adrenal gland pheochromocytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6716,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070325",
          "GARD:0025907",
          "GTR:AN0102113",
          "MEDGEN:859271",
          "NCIT:C118822",
          "UMLS:C3899677"
        ],
        "synonyms": [
          "childhood adrenal gland pheochromocytoma",
          "pheochromocytoma, childhood"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare pheochromocytoma of the adrenal gland that occurs during childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044767"
    }
  ],
  "roots": [
    {
      "id": 6798,
      "label": "neoplasm"
    }
  ]
}