{
  "id": 20337,
  "label": "intraductal breast papilloma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021097",
  "properties": {
    "xrefs": [
      "DOID:1626",
      "MEDGEN:65944",
      "NCIT:C3863",
      "SCTID:254848002",
      "SCTID:99571000119102",
      "UMLS:C0238034"
    ],
    "synonyms": [
      "breast papilloma",
      "duct papilloma of breast",
      "duct papilloma of the breast",
      "ductal breast papilloma",
      "intraductal breast papilloma",
      "intraductal papilloma of breast",
      "intraductal papilloma of the breast",
      "mammary duct papilloma",
      "papilloma of breast",
      "papilloma of the breast",
      "breast duct papilloma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A benign papillary neoplasm that arises anywhere in the ductal system of the breast. It is characterized by fibrovascular structures lined by benign epithelial and myoepithelial proliferations. Intraductal breast papillomas are classified as central, when they arise in large ducts, or peripheral, when they arise in the terminal ductal lobular units."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 3027,
      "label": "breast benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3039,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060082",
          "ICD10CM:D24",
          "ICD9:217",
          "MEDGEN:91085",
          "NCIT:C4505",
          "SCTID:269485000",
          "UMLS:C0346156",
          "icd11.foundation:2120366482"
        ],
        "synonyms": [
          "benign breast neoplasm",
          "benign breast tumor",
          "benign breast tumour",
          "benign neoplasm of breast",
          "benign neoplasm of the breast",
          "benign tumor of breast",
          "benign tumor of the breast",
          "benign tumour of breast",
          "benign tumour of the breast",
          "breast benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm arising from the breast parenchyma."
      },
      "child_count": 30,
      "reference_id": "MONDO:0000620"
    },
    {
      "id": 3052,
      "label": "integumentary system benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4198,
        6887
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060121"
        ],
        "synonyms": [
          "integumental system benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the integumental system."
      },
      "child_count": 16,
      "reference_id": "MONDO:0000652"
    },
    {
      "id": 4204,
      "label": "intraductal papilloma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4462
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1627",
          "ICDO:8503/0",
          "MEDGEN:61667",
          "MESH:D018300",
          "NCIT:C3785",
          "UMLS:C0206713",
          "icd11.foundation:288706574"
        ],
        "synonyms": [
          "duct adenoma",
          "duct papilloma",
          "ductal papilloma",
          "intraductal papilloma",
          "intraductal papilloma (morphologic abnormality)"
        ],
        "definition": "An intraluminal papillary epithelial neoplasm arising within the ducts. Representative examples are the intraductal breast papilloma and the salivary gland intraductal papilloma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002060"
    },
    {
      "id": 4205,
      "label": "intraductal papillary breast neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4567
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1628",
          "MEDGEN:233572",
          "NCIT:C36090",
          "UMLS:C1334252"
        ],
        "synonyms": [
          "intraductal papillary breast neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant papillary neoplasm that arises anywhere in the ductal system of the breast. It is characterized by fibrovascular structures lined by epithelial proliferations. This category includes intraductal papilloma and intraductal papillary carcinoma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0002061"
    }
  ],
  "children": [
    {
      "id": 4484,
      "label": "intracystic papillary adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20337
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2682",
          "ICDO:8504/0",
          "MEDGEN:87229",
          "NCIT:C4191",
          "UMLS:C0334374"
        ],
        "synonyms": [
          "intracystic papillary adenoma (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A papillary epithelial neoplasm arising in a cystically dilated breast duct."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002388"
    },
    {
      "id": 6230,
      "label": "sclerosing breast papilloma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20337
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7984",
          "MEDGEN:233436",
          "NCIT:C27944",
          "UMLS:C1335932"
        ],
        "synonyms": [
          "Complex sclerosing papillary lesion",
          "Complex sclerosing papillary lesion of the breast",
          "sclerosing breast papilloma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A breast papilloma characterized by the presence of predominant sclerosing architectural features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004421"
    },
    {
      "id": 6307,
      "label": "central breast papilloma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20337
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8224",
          "MEDGEN:272446",
          "NCIT:C36087",
          "UMLS:C1332896"
        ],
        "synonyms": [
          "large duct breast papilloma",
          "solitary intraductal breast papilloma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign papillary neoplasm that arises in a large duct of the breast. It is characterized by the presence of a fibrovascular core that is lined by benign epithelial and myoepithelial proliferations. Patients usually present with nipple discharge."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004505"
    },
    {
      "id": 6308,
      "label": "microscopic breast papilloma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20337
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8225",
          "MEDGEN:233851",
          "NCIT:C36088",
          "UMLS:C1335390"
        ],
        "synonyms": [
          "microscopic breast papilloma",
          "peripheral breast papilloma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign papillary neoplasm that arises in a terminal ductal lobular unit. It is characterized by the presence of a fibrovascular core that is lined by benign epithelial and myoepithelial proliferations. Peripheral breast papillomas are often multiple and are usually found microscopically. Patients are often asymptomatic."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004506"
    },
    {
      "id": 6309,
      "label": "atypical breast papilloma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20337
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8227",
          "MEDGEN:233997",
          "NCIT:C36089",
          "UMLS:C1332346"
        ],
        "synonyms": [
          "atypical breast papilloma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "An intraductal papilloma of the breast characterized by the presence of focal epithelial atypia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004507"
    }
  ],
  "roots": [
    {
      "id": 3027,
      "label": "breast benign neoplasm"
    },
    {
      "id": 3052,
      "label": "integumentary system benign neoplasm"
    },
    {
      "id": 4204,
      "label": "intraductal papilloma"
    },
    {
      "id": 4205,
      "label": "intraductal papillary breast neoplasm"
    }
  ]
}