{
  "id": 20340,
  "label": "breast neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021100",
  "properties": {
    "xrefs": [
      "EFO:0003869",
      "ICD9:239.3",
      "MEDGEN:264172",
      "MESH:D001943",
      "NCIT:C2910",
      "ONCOTREE:BREAST",
      "SCTID:126926005",
      "UMLS:C1458155"
    ],
    "synonyms": [
      "breast neoplasm",
      "breast neoplasm (disease)",
      "breast tumor",
      "breast tumour",
      "neoplasm of breast",
      "neoplasm of the breast",
      "neoplasm, breast",
      "tumor of breast",
      "tumor of the breast",
      "tumour of breast",
      "tumour of the breast"
    ],
    "categories": [
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A benign or malignant neoplasm of the breast parenchyma. It can originate from the ducts, lobules or the breast adipose tissue. Breast neoplasms are much more common in females than males."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 11,
  "parents": [
    {
      "id": 4708,
      "label": "breast disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3463",
          "EFO:0009483",
          "ICD10CM:N60-N65",
          "ICD9:610-612",
          "ICD9:611.8",
          "ICD9:611.9",
          "MEDGEN:652",
          "MESH:D001941",
          "NCIT:C26709",
          "SCTID:79604008",
          "UMLS:C0006145"
        ],
        "synonyms": [
          "breast disease",
          "breast disease or disorder",
          "breast diseases",
          "breast disorder",
          "disease of breast",
          "disease or disorder of breast",
          "disorder of breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A disease involving the breast."
      },
      "child_count": 15,
      "reference_id": "MONDO:0002657"
    },
    {
      "id": 20518,
      "label": "neoplasm of thorax",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:C30-C39",
          "ICD9:239.89",
          "MEDGEN:11793",
          "NCIT:C3406",
          "SCTID:255058005",
          "UMLS:C0039981"
        ],
        "synonyms": [
          "neoplasm of the thorax",
          "neoplasm of thoracic segment of trunk",
          "thoracic neoplasm",
          "thoracic segment of trunk neoplasm",
          "thoracic segment of trunk neoplasm (disease)",
          "thoracic segment of trunk tumor",
          "thoracic segment of trunk tumour",
          "thoracic tumor",
          "thoracic tumour",
          "tumor of the thorax",
          "tumor of thoracic segment of trunk",
          "tumor of thorax",
          "tumour of the thorax",
          "tumour of thoracic segment of trunk",
          "tumour of thorax"
        ],
        "definition": "A neoplasm (disease) that involves the thoracic segment of trunk."
      },
      "child_count": 11,
      "reference_id": "MONDO:0021350"
    }
  ],
  "children": [
    {
      "id": 3027,
      "label": "breast benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3039,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060082",
          "ICD10CM:D24",
          "ICD9:217",
          "MEDGEN:91085",
          "NCIT:C4505",
          "SCTID:269485000",
          "UMLS:C0346156",
          "icd11.foundation:2120366482"
        ],
        "synonyms": [
          "benign breast neoplasm",
          "benign breast tumor",
          "benign breast tumour",
          "benign neoplasm of breast",
          "benign neoplasm of the breast",
          "benign tumor of breast",
          "benign tumor of the breast",
          "benign tumour of breast",
          "benign tumour of the breast",
          "breast benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm arising from the breast parenchyma."
      },
      "child_count": 30,
      "reference_id": "MONDO:0000620"
    },
    {
      "id": 4562,
      "label": "nipple neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4198,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3003",
          "MEDGEN:205111",
          "NCIT:C5212",
          "UMLS:C1112166"
        ],
        "synonyms": [
          "neoplasm of nipple",
          "neoplasm of the nipple",
          "nipple neoplasm",
          "nipple neoplasm (disease)",
          "nipple tumor",
          "nipple tumour",
          "tumor of nipple",
          "tumor of the nipple",
          "tumour of nipple",
          "tumour of the nipple"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that arises in the area of the nipple."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002482"
    },
    {
      "id": 4563,
      "label": "breast myoepithelial tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4477,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3004",
          "MEDGEN:267411",
          "NCIT:C40389",
          "UMLS:C1511319"
        ],
        "synonyms": [
          "breast myoepithelial neoplasm",
          "breast myoepithelial tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant tumor that arises from the breast and originates from or is composed of myoepithelial cells. Representative examples include adenomyoepithelioma, myoepitheliosis, and malignant myoepithelioma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002483"
    },
    {
      "id": 4564,
      "label": "breast neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19314,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3009",
          "GARD:0023146",
          "MEDGEN:231969",
          "NCIT:C5169",
          "UMLS:C1332635"
        ],
        "synonyms": [
          "breast NET",
          "breast endocrine neoplasm",
          "breast neuroendocrine neoplasm",
          "breast neuroendocrine tumor",
          "breast neuroendocrine tumor, well differentiated, low or intermediate grade",
          "breast neuroendocrine tumour",
          "neuroendocrine neoplasm of breast",
          "neuroendocrine neoplasm of the breast",
          "neuroendocrine tumour of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm that arises from the breast and is composed of cells of neuroendocrine origin. Most cases are neuroendocrine carcinomas. Primary carcinoid tumors of the breast are very rare."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002485"
    },
    {
      "id": 4566,
      "label": "breast granular cell tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7788,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3011",
          "GARD:0023147",
          "MEDGEN:307309",
          "NCIT:C40400",
          "UMLS:C1511312"
        ],
        "synonyms": [
          "breast granular cell tumor",
          "granular cell tumor of breast",
          "granular cell tumour of breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A usually benign neoplasm that arises from the breast. It presents as a single, firm, and painless mass. It is characterized by the presence of neoplastic cells with eosinophilic granular cytoplasm."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002487"
    },
    {
      "id": 4567,
      "label": "intraductal breast neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3013",
          "MEDGEN:184927",
          "NCIT:C36083",
          "UMLS:C0948967"
        ],
        "synonyms": [
          "intraductal breast neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant epithelial neoplasm that arises anywhere in the ductal system of the breast. This category includes intraductal papilloma, intraductal papillary carcinoma, ductal hyperplasia with or without atypia, and ductal carcinoma in situ."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002488"
    },
    {
      "id": 5342,
      "label": "breast hemangiopericytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6821,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5370",
          "MEDGEN:267766",
          "NCIT:C40396",
          "UMLS:C1511313"
        ],
        "synonyms": [
          "breast hemangiopericytoma",
          "breast spindle cell tumor",
          "breast spindle cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A hemangiopericytoma arising from the breast."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003411"
    },
    {
      "id": 7686,
      "label": "breast fibrosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4198,
        5604,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10353",
          "EFO:1000145",
          "ICD10CM:N60.3",
          "ICD9:610.3",
          "MEDGEN:57627",
          "NCIT:C3660",
          "SCTID:29070004",
          "UMLS:C0156318"
        ],
        "synonyms": [
          "breast fibrosclerosis",
          "breast fibrosis",
          "fibrosclerosis of breast",
          "fibrosclerosis of the breast",
          "fibrosis of breast",
          "fibrosis of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "Breast fibrocystic change characterized by the prominence of fibrotic changes in the parenchyma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006118"
    },
    {
      "id": 8659,
      "label": "breast cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5215,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1612",
          "ICD10CM:C50",
          "ICD9:174.8",
          "MEDGEN:651",
          "NCIT:C9335",
          "SCTID:254837009",
          "UMLS:C0006142",
          "icd11.foundation:1047754165"
        ],
        "synonyms": [
          "breast tumor",
          "breast tumour",
          "mammary tumor",
          "mammary tumour",
          "breast cancer",
          "cancer of breast",
          "malignant breast neoplasm",
          "malignant breast tumor",
          "malignant breast tumour",
          "malignant neoplasm of breast",
          "malignant neoplasm of the breast",
          "malignant tumor of breast",
          "malignant tumor of the breast",
          "malignant tumour of breast",
          "malignant tumour of the breast",
          "primary breast cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males."
      },
      "child_count": 12,
      "reference_id": "MONDO:0007254"
    },
    {
      "id": 16600,
      "label": "benign ductal tumor of breast",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:180284"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0015874"
    },
    {
      "id": 20290,
      "label": "breast fibroepithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20289,
        20340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:267408",
          "NCIT:C40405",
          "ONCOTREE:BFN",
          "UMLS:C1511309"
        ],
        "synonyms": [
          "breast fibroepithelial neoplasm",
          "breast fibroepithelial tumor",
          "breast fibroepithelial tumour",
          "BFN",
          "breast fibroepithelial neoplasms"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant biphasic neoplasm that arises from the breast parenchyma. It is characterized by the presence of an epithelial and a mesenchymal (stromal) component. The typical examples are fibroadenoma and phyllodes tumor."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021046"
    }
  ],
  "roots": [
    {
      "id": 4708,
      "label": "breast disorder"
    },
    {
      "id": 20518,
      "label": "neoplasm of thorax"
    }
  ]
}