{
  "id": 20352,
  "label": "respiratory failure",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021113",
  "properties": {
    "xrefs": [
      "DOID:11162",
      "EFO:0009686",
      "ICD9:518.83",
      "MEDGEN:257837",
      "MESH:D012131",
      "NCIT:C26872",
      "SCTID:39871006",
      "UMLS:C1145670",
      "icd11.foundation:370028006"
    ],
    "synonyms": [
      "failure, respiratory",
      "respiratory failure",
      "acute respiratory failure",
      "chronic respiratory failure",
      "acute and chronic respiratory failure",
      "acute-on-chronic respiratory failure"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6971,
      "label": "lung disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2809
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:850",
          "EFO:0003818",
          "ICD9:518.89",
          "MEDGEN:7399",
          "MESH:D008171",
          "NCIT:C3198",
          "SCTID:19829001",
          "UMLS:C0024115"
        ],
        "synonyms": [
          "disease of lung",
          "disease or disorder of lung",
          "disorder of lung",
          "lung disease",
          "lung disease or disorder",
          "lung disorder",
          "lung disorders",
          "pulmonary disease",
          "pulmonary diseases",
          "pulmonary disorder",
          "pulmonary disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A disease involving the lung."
      },
      "child_count": 33,
      "reference_id": "MONDO:0005275"
    }
  ],
  "children": [
    {
      "id": 3448,
      "label": "acute respiratory failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20092,
        20352
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:J96.0",
          "ICD9:518.81",
          "MEDGEN:75540",
          "NCIT:C27043",
          "SCTID:65710008",
          "UMLS:C0264490",
          "icd11.foundation:875272781"
        ],
        "synonyms": [
          "acute respiratory failure",
          "respiratory failure, acute"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Life-threatening respiratory failure that develops rapidly. Causes include injury, sepsis, drug overdose, and pancreatitis. It manifests with dyspnea and cyanosis and may lead to cardiovascular shock."
      },
      "child_count": 6,
      "reference_id": "MONDO:0001208"
    },
    {
      "id": 23246,
      "label": "respiratory paralysis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7354,
        7990,
        20352
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025868",
          "MEDGEN:19748",
          "MESH:D012133",
          "SCTID:64228003",
          "UMLS:C0035232"
        ],
        "synonyms": [
          "paralysis of diaphragm",
          "diaphragmatic paralysis",
          "muscle paralysis, respiratory",
          "muscle paralyzes, respiratory",
          "paralysis, diaphragmatic",
          "paralysis, respiratory",
          "paralysis, respiratory muscle",
          "respiratory muscle paralysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Complete or severe weakness of the muscles of respiration. This condition may be associated with motor neuron diseases; peripheral nerve diseases; neuromuscular junction diseases; spinal cord diseases; injury to the phrenic nerve; and other disorders."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043775"
    }
  ],
  "roots": [
    {
      "id": 6971,
      "label": "lung disorder"
    }
  ]
}