{
  "id": 20354,
  "label": "luminal B breast carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021115",
  "properties": {
    "xrefs": [
      "DOID:0080674",
      "MEDGEN:770986",
      "NCIT:C53555",
      "UMLS:C3642346"
    ],
    "synonyms": [
      "Luminal B",
      "Luminal B breast cancer",
      "Luminal B breast carcinoma",
      "Luminal B estrogen receptor positive subtype of breast carcinoma",
      "Luminal B oestrogen receptor positive subtype of breast carcinoma",
      "Luminal B subtype of breast carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A biologic subset of breast carcinoma defined by low to moderate expression of genes characteristic of luminal epithelial cells including estrogen receptor (ER), and high expression of GGH, LAPTM4B, and CCNE1. This subtype of breast cancer is associated with a good prognosis, although not as favorable as the luminal A subtype."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6731,
      "label": "breast tumor luminal A or B",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7684
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060548",
          "EFO:0000306"
        ],
        "synonyms": [
          "breast tumor luminal",
          "breast tumour luminal",
          "luminal breast cancer",
          "luminal breast carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "Subsets of breast carcinoma defined by expression of genes characteristic of luminal epithelial cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004990"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6731,
      "label": "breast tumor luminal A or B"
    }
  ]
}