{
  "id": 20355,
  "label": "luminal A breast carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021116",
  "properties": {
    "xrefs": [
      "MEDGEN:770985",
      "NCIT:C53554",
      "UMLS:C3642345"
    ],
    "synonyms": [
      "Luminal A",
      "Luminal A breast cancer",
      "Luminal A breast carcinoma",
      "Luminal A estrogen receptor positive subtype of breast carcinoma",
      "Luminal A oestrogen receptor positive subtype of breast carcinoma",
      "Luminal A subtype of breast carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A biologic subset of breast carcinoma defined by high expression of genes characteristic of luminal epithelial cells, including estrogen receptor (ER), estrogen regulated protein LIV-1, and the transcription factors hepatocyte nuclear factor 3, HNF3A, XBP1, and GATA 3. This subtype of breast cancer is associated with a good prognosis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6731,
      "label": "breast tumor luminal A or B",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7684
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060548",
          "EFO:0000306"
        ],
        "synonyms": [
          "breast tumor luminal",
          "breast tumour luminal",
          "luminal breast cancer",
          "luminal breast carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "Subsets of breast carcinoma defined by expression of genes characteristic of luminal epithelial cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004990"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6731,
      "label": "breast tumor luminal A or B"
    }
  ]
}