{
  "id": 20362,
  "label": "female infertility",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021124",
  "properties": {
    "xrefs": [
      "EFO:0008560",
      "ICD10CM:N97",
      "ICD10WHO:N97",
      "ICD9:628.8",
      "ICD9:628.9",
      "MEDGEN:5795",
      "MESH:D007247",
      "SCTID:6738008",
      "UMLS:C0021361",
      "icd11.foundation:1237004558"
    ],
    "synonyms": [
      "female infertility",
      "female reproductive system infertility",
      "female reproductive system infertility disorder",
      "infertility disorder of female reproductive system",
      "female sterility",
      "female sub-fertility",
      "female subfertility",
      "postpartum sterility",
      "sterility, female",
      "sterility, postpartum",
      "sub fertility, female",
      "sub-fertility, female",
      "subfertility, female"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "Diminished or absent ability of a female to achieve conception."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4379,
      "label": "female reproductive system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6772
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:229",
          "EFO:0009549",
          "ICD9:629.9",
          "MEDGEN:65928",
          "MESH:D005831",
          "NCIT:C27020",
          "SCTID:310789003",
          "UMLS:C0236100"
        ],
        "synonyms": [
          "disease of female reproductive system",
          "disease or disorder of female reproductive system",
          "disorder of female genital system",
          "disorder of female reproductive system",
          "female reproductive disease",
          "female reproductive system disease",
          "female reproductive system disease or disorder",
          "female reproductive system disorder",
          "disease of female genital system",
          "disorder of female genital tract",
          "gynaecological disease",
          "gynecological disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A disease involving the female reproductive system."
      },
      "child_count": 34,
      "reference_id": "MONDO:0002263"
    },
    {
      "id": 6779,
      "label": "infertility disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6772
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5223",
          "EFO:0000545",
          "MEDGEN:43876",
          "MESH:D007246",
          "NCIT:C3836",
          "UMLS:C0021359"
        ],
        "synonyms": [
          "Sterile",
          "fertility disorders",
          "infertile",
          "sterile",
          "sterility",
          "infertility"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Inability to conceive for at least one year after trying and having unprotected sex. Causes of female infertility include endometriosis, fallopian tubes obstruction, and polycystic ovary syndrome. Causes of male infertility include abnormal sperm production or function, blockage of the epididymis, blockage of the ejaculatory ducts, hypospadias, exposure to pesticides, and health related issues."
      },
      "child_count": 5,
      "reference_id": "MONDO:0005047"
    }
  ],
  "children": [
    {
      "id": 3939,
      "label": "female infertility of uterine origin",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4705,
        20362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13589",
          "ICD10CM:N97.2",
          "ICD9:628.3",
          "MEDGEN:510285",
          "SCTID:26899006",
          "UMLS:C0156416"
        ],
        "synonyms": [
          "infertility, female, of uterine origin"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001753"
    },
    {
      "id": 15344,
      "label": "female infertility due to zona pellucida defect",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        15758,
        20362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017675",
          "MEDGEN:862728",
          "OMIM:615774",
          "Orphanet:404466",
          "UMLS:C4014291"
        ],
        "synonyms": [
          "OOMD",
          "OOMD1",
          "oocyte maturation defect",
          "oocyte maturation defect 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Female infertility due to zona pellucida defect is a rare, genetic, female infertility disorder characterized by the presence of abnormal oocytes that lack a zona pellucida. Affected individuals are unable to conceive despite having normal menstrual cycles and sex hormone levels, as well as no obstructions in the fallopian tubes or defects of the uterus or adnexa."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014342"
    },
    {
      "id": 19578,
      "label": "inherited primary ovarian failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7067,
        16330,
        20362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019294",
          "MEDGEN:443920",
          "OMIMPS:311360",
          "Orphanet:95710",
          "UMLS:C2930861"
        ],
        "synonyms": [
          "hereditary primary ovarian failure",
          "inherited POI",
          "inherited premature ovarian failure",
          "inherited primary ovarian insufficiency",
          "non-acquired premature ovarian failure"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An instance of primary ovarian failure that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 164,
      "reference_id": "MONDO:0019852"
    },
    {
      "id": 23360,
      "label": "female infertility due to oocyte meiotic arrest",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017887",
          "MEDGEN:1798912",
          "Orphanet:488191",
          "UMLS:C5567489"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0044626"
    }
  ],
  "roots": [
    {
      "id": 4379,
      "label": "female reproductive system disorder"
    },
    {
      "id": 6779,
      "label": "infertility disorder"
    }
  ]
}