{
  "id": 20418,
  "label": "neuroepithelial neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021193",
  "properties": {
    "xrefs": [
      "MEDGEN:60215",
      "MESH:D018302",
      "NCIT:C3787",
      "ONCOTREE:PRNET",
      "UMLS:C0206715"
    ],
    "synonyms": [
      "neoplasm of neuroepithelial tissue",
      "neoplasm of neuroepithelium",
      "neoplasm of the neuroepithelium",
      "neuroepithelial neoplasm",
      "neuroepithelial neoplasms",
      "neuroepithelial tissue neoplasm",
      "neuroepithelial tissue tumor",
      "neuroepithelial tissue tumour",
      "neuroepithelial tumor",
      "neuroepithelial tumors",
      "neuroepithelial tumour",
      "neuroepithelial tumours",
      "tumor of neuroepithelial tissue",
      "tumor of neuroepithelium",
      "tumor of the neuroepithelium",
      "tumour of neuroepithelial tissue",
      "tumour of neuroepithelium",
      "tumour of the neuroepithelium",
      "primary neuroepithelial tumor",
      "primary neuroepithelial tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A neoplasm of the nervous system that arises from the neuroepithelial tissues. Representative examples include astrocytic tumors, oligodendroglial tumors, ependymal tumors, and primitive neuroectodermal tumors."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 20456,
      "label": "nervous system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        6799
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:45046",
          "NCIT:C3268",
          "UMLS:C0027766"
        ],
        "synonyms": [
          "neoplasm of nervous system",
          "neoplasm of the nervous system",
          "nervous system neoplasm (disease)",
          "nervous system neoplasms",
          "nervous system tumor",
          "nervous system tumour",
          "tumor of nervous system",
          "tumor of the nervous system",
          "tumour of nervous system",
          "tumour of the nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the nervous system."
      },
      "child_count": 14,
      "reference_id": "MONDO:0021248"
    }
  ],
  "children": [
    {
      "id": 7121,
      "label": "primitive neuroectodermal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7212,
        20418
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:171",
          "EFO:0005235",
          "ICDO:9473/3",
          "ICDO:9503/3",
          "MEDGEN:64627",
          "MESH:D017599",
          "NCIT:C3716",
          "ONCOTREE:PNET",
          "UMLS:C0206663"
        ],
        "synonyms": [
          "PNET",
          "neuroectodermal neoplasm",
          "neuroectodermal tumor",
          "neuroectodermal tumour",
          "primitive neuroectodermal neoplasm",
          "primitive neuroectodermal tumor",
          "primitive neuroectodermal tumor (PNET)",
          "primitive neuroectodermal tumour (PNET)",
          "neuroepithelioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm that originates in the neuroectoderm. The neuroectoderm constitutes the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems and includes some glial cell precursors."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005462"
    },
    {
      "id": 17180,
      "label": "papillary tumor of the pineal region",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20418,
        20442
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081251",
          "GARD:0020725",
          "ICDO:9395/3",
          "MEDGEN:457445",
          "NCIT:C92624",
          "ONCOTREE:PTPR",
          "Orphanet:251915",
          "UMLS:C2985219"
        ],
        "synonyms": [
          "PTPR"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Papillary tumor of the pineal region (PTPR) is a very rare neoplasm of the pineal region that is thought to arise from the specialized ependymocytes of the subcommissural organ and that manifests with visual disturbances, headaches, loss of coordination and balance, nausea and vomiting due to obstructive hydrocephalus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016724"
    },
    {
      "id": 17182,
      "label": "mixed neuronal-glial tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20418
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020728",
          "MEDGEN:105377",
          "NCIT:C4747",
          "Orphanet:251934",
          "UMLS:C0474844",
          "icd11.foundation:1792897751"
        ],
        "synonyms": [
          "neuronal and Glio-neuronal neoplasm",
          "neuronal and Glio-neuronal tumor",
          "neuronal and Glio-neuronal tumour",
          "neuronal and mixed neuronal-glial tumor",
          "neuronal and mixed neuronal-glial tumors",
          "neuronal and mixed neuronal-glial tumour",
          "neuronal and mixed neuronal-glial tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of central nervous system neoplasms with a variable amount of neuronal and, less consistently, glial differentiation. They occur at a low frequency and usually carry a favorable prognosis. Representative examples include dysplastic cerebellar gangliocytoma, desmoplastic infantile ganglioglioma, desmoplastic infantile astrocytoma, and dysembryoplastic neuroepithelial tumor. (Adapted from WHO)"
      },
      "child_count": 12,
      "reference_id": "MONDO:0016729"
    },
    {
      "id": 17429,
      "label": "neuroepithelioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20418
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0003963",
          "Orphanet:2677",
          "icd11.foundation:841824628"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Peripheral neuroepithelioma is a rare noncentral nervous system tumor with evidence of primitive neuroectodermal differentiation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017046"
    },
    {
      "id": 20287,
      "label": "glioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20418
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005543",
          "GARD:0006513",
          "MEDGEN:9030",
          "MESH:D005910",
          "NCIT:C3059",
          "Orphanet:182067",
          "SCTID:393564001",
          "UMLS:C0017638"
        ],
        "synonyms": [
          "glial neoplasm",
          "glial tumor",
          "glial tumour",
          "glioma",
          "neoplasm of neuroglia",
          "neoplasm of the neuroglia",
          "neuroglial neoplasm",
          "neuroglial tumor",
          "neuroglial tumour",
          "tumor of neuroglia",
          "tumor of the neuroglia",
          "tumour of neuroglia",
          "tumour of the neuroglia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas."
      },
      "child_count": 9,
      "reference_id": "MONDO:0021042"
    },
    {
      "id": 21613,
      "label": "pineal parenchymal cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20418,
        20442
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:9360/1",
          "NCIT:C6965"
        ],
        "synonyms": [
          "neoplasm of pineal gland",
          "neoplasm of the pineal gland",
          "pineal gland neoplasm",
          "pineal gland tumor",
          "pineal gland tumour",
          "pineal parenchymal cell neoplasm",
          "pineal parenchymal cell tumor",
          "pineal parenchymal cell tumour",
          "pineal parenchymal neoplasm",
          "pineal parenchymal tumor",
          "pineal parenchymal tumour",
          "pineocytic neoplasm",
          "pineocytic tumor",
          "pineocytic tumour",
          "tumor of pineal gland",
          "tumor of the pineal gland",
          "tumour of pineal gland",
          "tumour of the pineal gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm arising from the pineocyte, a cell with photosensory and neuroendocrine functions. It may be composed of mature elements or primitive, immature cells. The cellular composition determines the biological behavior and clinical outcome. Three types are recognized: pineoblastoma, pineocytoma, and pineal parenchymal tumor of intermediate differentiation (Adapted from WHO.)"
      },
      "child_count": 6,
      "reference_id": "MONDO:0024890"
    }
  ],
  "roots": [
    {
      "id": 20456,
      "label": "nervous system neoplasm"
    }
  ]
}