{
  "id": 20427,
  "label": "heart neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021209",
  "properties": {
    "xrefs": [
      "EFO:1001339",
      "GARD:0002619",
      "MEDGEN:9172",
      "NANDO:2100061",
      "NANDO:2200236",
      "NCIT:C3081",
      "UMLS:C0018809"
    ],
    "synonyms": [
      "Cardiac neoplasm",
      "Cardiac neoplasms",
      "Cardiac tumor",
      "Cardiac tumour",
      "heart neoplasm (disease)",
      "heart tumor",
      "heart tumour",
      "neoplasm of heart",
      "neoplasm of the heart",
      "tumor of heart",
      "tumor of the heart",
      "tumour of heart",
      "tumour of the heart",
      "Intracavitary tumors",
      "Intracavitary tumours",
      "myocardial tumors (rhabdomyomas and fibromas)",
      "myocardial tumours (rhabdomyomas and fibromas)",
      "primary cardiac tumors, childhood"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A neoplasm (disease) that involves the heart."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 6967,
      "label": "heart disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:114",
          "EFO:0003777",
          "ICD9:429.89",
          "ICD9:429.9",
          "ICD9:V47.2",
          "MEDGEN:5458",
          "MESH:D006331",
          "NCIT:C3079",
          "SCTID:56265001",
          "UMLS:C0018799",
          "icd11.foundation:1512587470"
        ],
        "synonyms": [
          "cardiac disease",
          "disease of heart",
          "disease or disorder of heart",
          "disorder of heart",
          "disorder of heart/pericardium",
          "heart disease",
          "heart disease or disorder",
          "heart disorder",
          "heart trouble",
          "heart/pericardial disease",
          "heart/pericardial disease or disorder",
          "heart/pericardial disorder",
          "heart/pericardial trouble"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the heart and/or pericardium."
      },
      "child_count": 34,
      "reference_id": "MONDO:0005267"
    },
    {
      "id": 20518,
      "label": "neoplasm of thorax",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:C30-C39",
          "ICD9:239.89",
          "MEDGEN:11793",
          "NCIT:C3406",
          "SCTID:255058005",
          "UMLS:C0039981"
        ],
        "synonyms": [
          "neoplasm of the thorax",
          "neoplasm of thoracic segment of trunk",
          "thoracic neoplasm",
          "thoracic segment of trunk neoplasm",
          "thoracic segment of trunk neoplasm (disease)",
          "thoracic segment of trunk tumor",
          "thoracic segment of trunk tumour",
          "thoracic tumor",
          "thoracic tumour",
          "tumor of the thorax",
          "tumor of thoracic segment of trunk",
          "tumor of thorax",
          "tumour of the thorax",
          "tumour of thoracic segment of trunk",
          "tumour of thorax"
        ],
        "definition": "A neoplasm (disease) that involves the thoracic segment of trunk."
      },
      "child_count": 11,
      "reference_id": "MONDO:0021350"
    },
    {
      "id": 21585,
      "label": "cardiovascular neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736,
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:105422",
          "NCIT:C4784",
          "SCTID:721573003",
          "UMLS:C0497243"
        ],
        "synonyms": [
          "cardiovascular neoplasm",
          "cardiovascular system neoplasm",
          "cardiovascular system tumor",
          "cardiovascular system tumour",
          "cardiovascular tumor",
          "cardiovascular tumour",
          "neoplasm of cardiovascular system",
          "tumor of cardiovascular system",
          "tumour of cardiovascular system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the heart and/or vessels. Representative examples of benign neoplasms include atrial myxoma, hemangioma, and lymphangioma. Representative examples of malignant neoplasms include pericardial malignant mesothelioma and angiosarcoma."
      },
      "child_count": 10,
      "reference_id": "MONDO:0024757"
    }
  ],
  "children": [
    {
      "id": 3568,
      "label": "heart cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4237,
        5215,
        20427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:117",
          "GARD:0027573",
          "ICD10CM:C38.0",
          "ICD9:164.1",
          "MEDGEN:57787",
          "MESH:D006338",
          "NCIT:C3548",
          "UMLS:C0153500"
        ],
        "synonyms": [
          "Cardiac tumor",
          "Cardiac tumour",
          "tumor of heart",
          "tumour of heart",
          "Cardiac neoplasm, malignant",
          "cancer of heart",
          "heart cancer",
          "malignant Cardiac neoplasm",
          "malignant Cardiac tumor",
          "malignant Cardiac tumour",
          "malignant heart neoplasm",
          "malignant heart tumor",
          "malignant heart tumour",
          "malignant neoplasm of heart",
          "malignant neoplasm of the heart",
          "malignant tumor of heart",
          "malignant tumor of the heart",
          "malignant tumour of heart",
          "malignant tumour of the heart"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the heart"
      },
      "child_count": 21,
      "reference_id": "MONDO:0001340"
    },
    {
      "id": 5623,
      "label": "heart malignant hemangiopericytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6821,
        20427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6034",
          "GARD:0027645",
          "MEDGEN:233144",
          "NCIT:C5365",
          "UMLS:C1334567"
        ],
        "synonyms": [
          "heart hemangiopericytoma",
          "heart spindle cell tumor",
          "heart spindle cell tumour",
          "malignant Cardiac hemangiopericytoma",
          "malignant heart hemangiopericytoma",
          "malignant hemangiopericytoma of heart",
          "malignant hemangiopericytoma of the heart"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant hemangiopericytoma arising in the heart."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003743"
    },
    {
      "id": 10932,
      "label": "familial atrial myxoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20427,
        24272
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000139",
          "MEDGEN:419902",
          "MESH:C538262",
          "OMIM:255960",
          "Orphanet:615",
          "SCTID:233855002",
          "UMLS:C2931787",
          "icd11.foundation:1491085859"
        ],
        "synonyms": [
          "MYXOMA, intracardiac",
          "atrial Myxoma, familial",
          "intracardiac myxoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0009719"
    },
    {
      "id": 19312,
      "label": "primary adult heart tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018709",
          "MEDGEN:900582",
          "Orphanet:874",
          "SCTID:715403006",
          "UMLS:C4275152",
          "icd11.foundation:1784866291"
        ],
        "synonyms": [
          "adult cardiac tumor",
          "adult cardiac tumour",
          "adult heart tumor",
          "adult heart tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Adult heart tumor refers to neoplasms of the heart that manifest in adults and generally present with a variety of non-specific manifestations (depending on tumor site and infiltration) such as weight loss, exhaustion, hemorrhagic pericardial effusion, heart failure, arrhythmias, and embolisms, or that can also be asymptomatic. In adults 75% of heart tumors are benign, with myxoma being the most common benign tumor (accounting for 50-70% of all primary heart tumors) and rhabdomyosarcoma comprising 75% of malignant heart tumors. Other malignant tumors of the heart include fibrosarcoma and leiomyosarcoma (see these terms)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019493"
    },
    {
      "id": 19313,
      "label": "primary pediatric heart tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018710",
          "MEDGEN:895113",
          "Orphanet:875",
          "UMLS:C4274356"
        ],
        "synonyms": [
          "Cardiac tumor of child",
          "Cardiac tumour of child",
          "heart tumor of child",
          "heart tumour of child",
          "paediatric heart neoplasm",
          "pediatric heart neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Cardiac tumors are benign or malignant neoplasms arising primarily in the inner lining, muscle layer, or the surrounding pericardium of the heart. They can be primary or metastatic."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019494"
    },
    {
      "id": 20026,
      "label": "cardiac germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18334,
        20427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025182",
          "MEDGEN:1633290",
          "NCIT:C147005",
          "UMLS:C4687640"
        ],
        "synonyms": [
          "cardiac germ cell tumor",
          "heart germ cell tumor",
          "heart germ cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A germ cell tumor that arises within the myocardium or cardiac chambers. The reported cases have been teratomas and yolk sac tumors."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020589"
    },
    {
      "id": 20536,
      "label": "neoplasm of endocardium",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2931,
        20427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027897",
          "ICD9:239.89",
          "MEDGEN:220938",
          "NCIT:C5346",
          "SCTID:126731002",
          "UMLS:C1290401"
        ],
        "synonyms": [
          "endocardial neoplasm",
          "endocardial tumor",
          "endocardial tumour",
          "endocardium neoplasm",
          "endocardium neoplasm (disease)",
          "endocardium tumor",
          "endocardium tumour",
          "neoplasm of endocardium",
          "neoplasm of the endocardium",
          "tumor of endocardium",
          "tumor of the endocardium",
          "tumour of endocardium",
          "tumour of the endocardium"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the endocardium."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021378"
    },
    {
      "id": 20537,
      "label": "neoplasm of epicardium",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20427,
        20539
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027898",
          "ICD9:239.89",
          "MEDGEN:224850",
          "NCIT:C5347",
          "SCTID:126733004",
          "UMLS:C1290403"
        ],
        "synonyms": [
          "epicardial neoplasm",
          "epicardial tumor",
          "epicardial tumour",
          "epicardium neoplasm",
          "epicardium neoplasm (disease)",
          "epicardium tumor",
          "epicardium tumour",
          "neoplasm of epicardium",
          "neoplasm of the epicardium",
          "tumor of epicardium",
          "tumor of the epicardium",
          "tumour of epicardium",
          "tumour of the epicardium"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the epicardium."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021379"
    },
    {
      "id": 20538,
      "label": "neoplasm of myocardium",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20427,
        21552
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027899",
          "ICD9:239.89",
          "MEDGEN:266216",
          "NCIT:C5349",
          "SCTID:126732009",
          "UMLS:C1290402"
        ],
        "synonyms": [
          "myocardial neoplasm",
          "myocardial tumor",
          "myocardial tumour",
          "myocardium neoplasm",
          "myocardium neoplasm (disease)",
          "myocardium tumor",
          "myocardium tumour",
          "neoplasm of myocardium",
          "neoplasm of the myocardium",
          "tumor of myocardium",
          "tumor of the myocardium",
          "tumour of myocardium",
          "tumour of the myocardium"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the myocardium."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021380"
    },
    {
      "id": 20572,
      "label": "benign neoplasm of heart",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3034,
        3039,
        20427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027900",
          "ICD10CM:D15.1",
          "ICD9:212.7",
          "MEDGEN:57807",
          "NCIT:C3605",
          "SCTID:92132009",
          "UMLS:C0153957",
          "icd11.foundation:991198048"
        ],
        "synonyms": [
          "benign Cardiac neoplasm",
          "benign Cardiac tumor",
          "benign Cardiac tumour",
          "benign heart neoplasm",
          "benign heart tumor",
          "benign heart tumour",
          "benign neoplasm of the heart",
          "benign tumor of heart",
          "benign tumor of the heart",
          "benign tumour of heart",
          "benign tumour of the heart",
          "heart benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the heart."
      },
      "child_count": 15,
      "reference_id": "MONDO:0021450"
    }
  ],
  "roots": [
    {
      "id": 6967,
      "label": "heart disorder"
    },
    {
      "id": 20518,
      "label": "neoplasm of thorax"
    },
    {
      "id": 21585,
      "label": "cardiovascular neoplasm"
    }
  ]
}